Zobrazeno 1 - 10
of 14
pro vyhledávání: '"cytology [Embryonic Stem Cells]"'
Autor:
Langkabel, Jan, Horne, Arik, Bonaguro, Lorenzo, Holsten, Lisa, Hesse, Tatiana, Knaus, Alexej, Riedel, Yannick, Becker, Matthias, Händler, Kristian, Elmzzahi, Tarek, Bassler, Kevin, Reusch, Nico, Yeghiazarian, Leon Harootoonovtch, Pecht, Tal, Saglam, Adem, Ulas, Thomas, Aschenbrenner, Anna C., Kaiser, Franziska, Kubaczka, Caroline, Schultze, Joachim L., Schorle, Hubert
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications
Nature Communications 12(1), 7322 (2021). doi:10.1038/s41467-021-27586-w
Nature Communications
Nature Communications 12(1), 7322 (2021). doi:10.1038/s41467-021-27586-w
Blastocyst-derived stem cell lines were shown to self-organize into embryo-like structures in 3D cell culture environments. Here, we provide evidence that embryo-like structures can be generated solely based on transcription factor-mediated reprogram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c76882489a9ac948b288557830b06ba4
https://doaj.org/article/4777dcfcfbcb4d98ae83f5dc3f98bef3
https://doaj.org/article/4777dcfcfbcb4d98ae83f5dc3f98bef3
Autor:
Marius Ader, Jochen Guck, Stylianos Michalakis, Oliver Otto, Madalena Carido, Mike O. Karl, Tiago Santos-Ferreira, Maik Herbig
Publikováno v:
Cytometry
Cytometry A
Cytometry / A 95(11), 1145-1157 (2019). doi:10.1002/cyto.a.23798
Cytometry A
Cytometry / A 95(11), 1145-1157 (2019). doi:10.1002/cyto.a.23798
Distinct cell‐types within the retina are mainly specified by morphological and molecular parameters, however, physical properties are increasingly recognized as a valuable tool to characterize and distinguish cells in diverse tissues. High‐throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a5a859872b0be8c480f58528cfa2b91
http://europepmc.org/articles/PMC6900160
http://europepmc.org/articles/PMC6900160
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 2 (2021)
Disease models & mechanisms 14(2), dmm047803 (2021). doi:10.1242/dmm.047803
Dis. Model. Mech. 14:dmm047803 (2021)
Disease Models & Mechanisms
article-version (VoR) Version of Record
Disease models & mechanisms 14(2), dmm047803 (2021). doi:10.1242/dmm.047803
Dis. Model. Mech. 14:dmm047803 (2021)
Disease Models & Mechanisms
article-version (VoR) Version of Record
Gene trapping is a high-throughput approach that has been used to introduce insertional mutations into the genome of mouse embryonic stem (ES) cells. It is performed with generic gene trap vectors that simultaneously mutate and report the expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126c1985eeec2ee888a6b678f6813bf7
http://dmm.biologists.org/content/14/2/dmm047803
http://dmm.biologists.org/content/14/2/dmm047803
Publikováno v:
Developmental biology 433(2), 132-143 (2018). doi:10.1016/j.ydbio.2017.09.028
A major cause for vision impairment and blindness in industrialized countries is the loss of the light-sensing retinal tissue in the eye. Photoreceptor damage is one of the main characteristics found in retinal degeneration diseases, such as Retiniti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9f7be63b504a49083bd94b532cb5d2
https://pubmed.ncbi.nlm.nih.gov/29291970
https://pubmed.ncbi.nlm.nih.gov/29291970
Autor:
Wolfgang Wurst, Luca Giovanni Di Giovannantonio, Dario Acampora, Michela Di Salvio, Antonio Simeone, Nilima Prakash, Daniela Omodei, Alessandra Pierani
Publikováno v:
Development 141, 377-388 (2014)
Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2014, 141 (2), pp.377-88. ⟨10.1242/dev.102954⟩
Development 141(2), 377-388 (2013). doi:10.1242/dev.102954
Development (Dublin, 1970) 141 (2014): 377. doi:10.1242/dev.102954
info:cnr-pdr/source/autori:Di Giovannantonio LG, Di Salvio M, Omodei D, Prakash N, Wurst W, Pierani A, Acampora D, Simeone A./titolo:Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity./doi:10.1242%2Fdev.102954/rivista:Development (Dublin, 1970)/anno:2014/pagina_da:/pagina_a:377/intervallo_pagine:377/volume:141
Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2014, 141 (2), pp.377-88. ⟨10.1242/dev.102954⟩
Development
Development (Dublin, 1970) 141 (2014): 377. doi:10.1242/dev.102954
info:cnr-pdr/source/autori:Di Giovannantonio LG, Di Salvio M, Omodei D, Prakash N, Wurst W, Pierani A, Acampora D, Simeone A./titolo:Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity./doi:10.1242%2Fdev.102954/rivista:Development (Dublin, 1970)/anno:2014/pagina_da:/pagina_a:377/intervallo_pagine:377/volume:141
International audience; During embryonic development, the rostral neuroectoderm is regionalized into broad areas that are subsequently subdivided into progenitor compartments with specialized identity and fate. These events are controlled by signals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ddcf08112bfaac466d50bdaef926928
https://doi.org/10.1242/dev.102954
https://doi.org/10.1242/dev.102954
Publikováno v:
Amyotrophic lateral sclerosis & frontotemporal degeneration 16(7-8), 431-441 (2015). doi:10.3109/21678421.2015.1055275
TAR DNA-binding protein 43 (TDP-43) and fused in sarcoma (FUS) were recently found to cause familial and sporadic amyotrophic lateral sclerosis (ALS). The mechanisms by which mutations within these genes cause ALS are not understood. We established m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c01c2623b0d27e3783ea1c973dd844e4
https://pub.dzne.de/record/138215
https://pub.dzne.de/record/138215
Autor:
Caroline Schall, Wolfgang Wurst, Andrew J. Washkowitz, Thomas Floss, Jesse Mager, Virginia E. Papaioannou, Kun Zhang
Publikováno v:
Development 142(1), 31-40 (2014). doi:10.1242/dev.111104
Development 142, 31-40 (2015)
Development 142, 31-40 (2015)
The maintenance and control of pluripotency is of great interest in stem cell biology. The dual specificity T-box/basic-helix-loop-helix-zipper transcription factor Mga is expressed in the pluripotent cells of the inner cell mass (ICM) and epiblast o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f586061fed95823a6462228ecf3f93c9
Autor:
Lisa Glasl, Elisabeth Kremmer, Dietrich Trümbach, Thomas Klopstock, Jan Rozman, Aladin Samara, Martin Klingenspor, Sebastian Koob, Wolfgang Wurst, Martin Hrabě de Angelis, Frauke Neff, Carola Stribl, Eckhard Wolf, Birgit Rathkolb, Manuela Neumann, Regina Peis, Lore Becker, Thomas Floss, Helmut Fuchs, Axel Walch, Sabine M. Hölter, Valerie Gailus-Durner, Wolfgang Hans, Andreas S. Reichert, Michaela Aichler, Johannes Beckers, Marion Horsch
Publikováno v:
The journal of biological chemistry 289(15), 10769-10784 (2014). doi:10.1074/jbc.M113.515940
The majority of amyotrophic lateral sclerosis (ALS) cases as well as many patients suffering from frontotemporal lobar dementia (FTLD) with ubiquitinated inclusion bodies show TDP-43 pathology, the protein encoded by the TAR DNA-binding protein (Tard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::500a8183473a2d621752f3ef269a3edd
https://pubmed.ncbi.nlm.nih.gov/25215360
https://pubmed.ncbi.nlm.nih.gov/25215360
Autor:
Claudia Kühne, Wolfgang Wurst, Jan M. Deussing, Jochen Graw, Martin Hrabě de Angelis, Günther Schütz, Oliver Puk
Publikováno v:
The journal of comparative neurology 520(14), 3150-3180 (2012). doi:10.1002/cne.23082
The corticotropin-releasing hormone (CRH) and its type 1 receptor (CRHR1) play a central role in coordinating the endocrine, autonomic, and behavioral responses to stress. A prerequisite to functionally dissect the complexity of the CRH/CRHR1 system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e019eac943d77a8470d9746a0e157190
https://pubmed.ncbi.nlm.nih.gov/22886732
https://pubmed.ncbi.nlm.nih.gov/22886732
Autor:
Alexander Kleger, Leonhard Linta, Holm Zaehres, Anja Böckers, Marianne Stockmann, Tobias M. Böckers, Gotthold Barbi, Alexander Storch, Stefan Liebau, Karin N. Kleinhans, Qiong Lin
Publikováno v:
Stem Cells and Development 21(6), 965-976 (2012). doi:10.1089/scd.2011.0026
Patient-specific human induced pluripotent stem (hiPS) cells not only provide a promising tool for cellular disease models in general, but also open up the opportunity to establish cell-type-specific systems for personalized medicine. One of the cruc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15fb2f7986638090cedb2c6786bd056c
https://pubmed.ncbi.nlm.nih.gov/21699413
https://pubmed.ncbi.nlm.nih.gov/21699413