Utility of B Cell Activating Factor (BAFF) and a Proliferation induced Ligand (APRIL) Cytokines as Markers of Response to Anti-Tubercular Therapy

Autor: Anuj Singhal, VK Sashindran, Ashwini Aggarwal, Arun Kumar Yadav, Suresh Kayastha

Publikováno v: Journal of Clinical and Diagnostic Research, Vol 14, Iss 5, Pp OC01-OC04 (2020)

Introduction: Serum estimation of cytokines, that play an important role in the pathogenesis of tuberculosis, may be useful to predict early response to Anti-Tubercular Therapy (ATT). This study will help in identifying the role of cytokines in predi

Externí odkaz: https://doaj.org/article/3d8a658c44024703a53631b356b8f63b

Multifunctional CD4(+) T cells correlate with active Mycobacterium tuberculosis infection

Autor: Giuseppe Gelsomino, Alfredo Salerno, Simone A. Joosten, Alessandro Sanduzzi, Domenico Galati, Francesco Dieli, Giuliana Guggino, Alessandro Matarese, Willeke P. J. Franken, Tom H. M. Ottenhoff, Paola Di Carlo, Lucina Titone, Nadia Caccamo, Marialuisa Bocchino

Publikováno v: European Journal of Immunology; Vol 40
European Journal of Immunology
European Journal of Immunology, 40(8), 2211-2220

Th1 CD4(+) T cells and their derived cytokines are crucial for protection against Mycobacterium tuberculosis. Using multiparametic flow cytometry, we have evaluated the distribution of seven distinct functional states (IFN-gamma/IL-2/TNF-alpha triple

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bca3cd80b91519eec4199e6bc44739e
https://pubmed.ncbi.nlm.nih.gov/20853500