Zobrazeno 1 - 10
of 52
pro vyhledávání: '"cytochromy P450"'
Autor:
Čillíková, Olívia
Targeted anti-tumor therapy is a modern and effective approach to cancer treatment. This type of therapy includes several groups of anticancer drugs. The second most commonly used group of targeted chemotherapeutic substances are tyrosinkinase inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2186::e759bd0dc391100a4a11859bada03926
http://www.nusl.cz/ntk/nusl-527916
http://www.nusl.cz/ntk/nusl-527916
Autor:
Slobodníková, Eva
Cabozantinib is an anti-cancer drug used mainly for the treatment of thyroid and renal cell carcinoma. It is classified as a low molecular weight selective tyrosine kinase inhibitor. Tyrosine kinases play a key role in signal transduction and regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2186::80e885aa421b521ef2dc0244bfddc53d
http://www.nusl.cz/ntk/nusl-527892
http://www.nusl.cz/ntk/nusl-527892
Autor:
Sedlmajer, Štěpán
Charles University Faculty of Pharmacy in Hradec Králové Department of Pharmacology and Toxicology Student: Štěpán Sedlmajer Supervisor: PharmDr. Tomáš Smutný, Ph.D. Title of diploma thesis: A role of microRNAs in the regulation of hepatic dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2186::aa36f0bc82428d2862911a15c2793eec
http://www.nusl.cz/ntk/nusl-528786
http://www.nusl.cz/ntk/nusl-528786
Autor:
Vančurová, Kateřina
Cancer is still one of the most common deaths in the world and therefore new drugs are needed to be developed to stop or slow down this disease. Recently, there has been a huge expansion in drug development. Cytostatics that are still widely used inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2186::fc3c2563a840090d7f50d1b4c2713336
http://www.nusl.cz/ntk/nusl-508005
http://www.nusl.cz/ntk/nusl-508005
Autor:
Kurshakova, Evgeniia
17-ethinylestradiol (EE2) is a synthetic derivative of the natural estrogen 17-estradiol. It is used in medicine as a key component of oral contraceptives. Due to its ability to modulate the functions of the endocrine system, EE2 belongs to the gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2186::785f4d7c9b9aa88182b4a2caa1be2d54
http://www.nusl.cz/ntk/nusl-508025
http://www.nusl.cz/ntk/nusl-508025
Autor:
Jurečka, Tomáš
Cabozantinib is an anticancer drug that inhibit tyrosine kinases which allow signal pathways important for growth and development of tumors. It is used for treatment of medullary thyroid cancer, hepatocellular carcinoma and kidney cancer. The major e
Externí odkaz:
http://www.nusl.cz/ntk/nusl-448795
Autor:
Jurečka, Tomáš
Cabozantinib is an anticancer drug that inhibit tyrosine kinases which allow signal pathways important for growth and development of tumors. It is used for treatment of medullary thyroid cancer, hepatocellular carcinoma and kidney cancer. The major e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2186::7d68ec5424a46f0cbe659fed4328b42c
http://www.nusl.cz/ntk/nusl-448795
http://www.nusl.cz/ntk/nusl-448795
Autor:
Fedák, Michal
Vandetanib is anticancer drug used mainly for targeted therapy of medullary thyroid carcinoma. It acts as inhibitor of tyrosine kinase and shows selectivity for vascular endothelial growth factor 2 (VEGFR-2) and epidermal growth factor (EGFR). It als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2186::21d5aadaa4d938652754edcd25bd92bf
http://www.nusl.cz/ntk/nusl-452824
http://www.nusl.cz/ntk/nusl-452824
Autor:
Janoušková, Adéla
Charles University Faculty of Pharmacy in Hradec Králové Department of Pharmacology & Toxicology Student: Adéla Janoušková Supervisor: RNDr. Jakub Hofman, Ph.D. Title of diploma thesis: Study on impact of selected protein kinase inhibitors on dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::54d27e61549fdda1c1e7762f8b71a2ec
http://www.nusl.cz/ntk/nusl-438395
http://www.nusl.cz/ntk/nusl-438395
Autor:
Ličko, Vojtech
Cytochrome b5 (CYB5) is heme protein capable of reduction of cytochromes P450 (CYP) or some other enzymes. However, his regulative capability was also observed by his apo form, i.e. in absence of heme prosthetic group in the active center. CYB5 can a
Externí odkaz:
http://www.nusl.cz/ntk/nusl-434085