Zobrazeno 1 - 10
of 2 348
pro vyhledávání: '"cyp450"'
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background In plants, Cytochrome P450 (CYP450) constitutes the largest family of metabolic enzymes and plays a crucial role in various physiological processes, including plant growth and development. Eggplants are well-known for their peel
Externí odkaz:
https://doaj.org/article/eec68f32da1f4b3981a5b8cd2fa5f7b1
Autor:
Miaogao Zhang, Zhenguo Qiu
Publikováno v:
Food & Nutrition Research, Vol 68, Pp 1-16 (2024)
In this study, (−)-epigallocatechin gallate (EGCG) and caffeine extracted from freeze-dried autumn Baiyedancong Oolong tea (FBOT) were orally administered to mice for 7 consecutive days to explore the effects of BOT and its bioactive compounds on t
Externí odkaz:
https://doaj.org/article/aae0d53b6cdd4a7cb071268a74579263
Publikováno v:
Pharmaceutical Biology, Vol 62, Iss 1, Pp 207-213 (2024)
AbstractContext The effect of the active ingredients in traditional Chinese medicines on the activity of cytochrome P450 enzymes (CYP450s) is a critical factor that should be considered in TCM prescriptions. Physcion, the major active ingredient of R
Externí odkaz:
https://doaj.org/article/9076d3cfdac24f38b558c0873708e599
Autor:
Nikhilesh Andhi, Bhuvana Darawadi
Publikováno v:
Journal of Indian College of Cardiology, Vol 14, Iss 3, Pp 79-87 (2024)
Globally, cardio vascular diseases (CVD) remain the primary cause of morbidity and mortality. Pharmacogenomics (PGxs) has profoundly changed how various drug classes are managed in CVDs. For example, genetic polymorphisms in genes such as SLCO1B1 imp
Externí odkaz:
https://doaj.org/article/e19165b17fd34855a347f887dc40e9ff
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background Hylurgus ligniperda (Coleoptera: Curculionidae) is a worldwide forest quarantine pest. It is widely distributed, has many host tree species, and possesses strong adaptability. To explore its environmental adaptability and the rela
Externí odkaz:
https://doaj.org/article/618ffe4ec91141809aabbae293632468
Publikováno v:
South Sustainability, Vol 5, Iss 2 (2024)
Hasta la actualidad, 5,8 millones de toneladas de petróleo han sido derramados en los océanos, y son los hidrocarburos aromáticos policíclicos (HAP) los compuestos que causan mayor impacto negativo en estos ecosistemas. Comprender cómo los organ
Externí odkaz:
https://doaj.org/article/cc41960d8b1345868ebfd2634c49bc8b
Publikováno v:
Pharmacology Research & Perspectives, Vol 12, Iss 5, Pp n/a-n/a (2024)
Abstract Cytochrome P450 enzymes (CYPs) play a crucial role in phase I metabolic reactions. The activity of CYPs would affect therapeutic efficacy and may even induce toxicity. Given the complex components of traditional Chinese medicine, it is impor
Externí odkaz:
https://doaj.org/article/294f58df30f4493bbd1b3a954493a7f4
Autor:
Yewen Chen, Jing Zhang, Jiayu Lu, Huifang Shi, Pengfei Lan, Wei Wang, Guangcai Ma, Xiaoxuan Wei, Xueyu Wang, Haiying Yu
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 284, Iss , Pp 116865- (2024)
Tebuconazole (TEB), a prominent chiral triazole fungicide, has been extensively utilized for plant pathogen control globally. Despite experimental evidence of TEB metabolism in mammals, the enantioselectivity in the biotransformation of R- and S-TEB
Externí odkaz:
https://doaj.org/article/1b09fa0d3e0f44d3a270a74e578196eb
Autor:
Yufei Xue, Shanshan Wang, Qiheng Zhang, Fangzhou Wu, Li Huang, Shujun Qin, Min Zhang, Xiao Yang, Zihan Deng, Huanhuan Jiang, Lejing Li, Yourong Chai
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 283, Iss , Pp 116792- (2024)
Cytochromes P450 monooxygenases (CYP450s) constitute the largest enzymic protein family that is widely present in plants, animals, and microorganisms, participate in numerous metabolic pathways, and play diverse roles in development, metabolism, and
Externí odkaz:
https://doaj.org/article/a34342e007fc4bccbeef227f5f4a2443
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract The persistent challenges posed by pollution and climate change are significant factors disrupting ecosystems, particularly aquatic environments. Numerous contaminants found in aquatic systems, such as ammonia and metal toxicity, play a cruc
Externí odkaz:
https://doaj.org/article/1cda3236ce954bfaa03926b4cf80af0b