Association of ST6GAL1 and CYP19A1 polymorphisms in the 3′-UTR with astrocytoma risk and prognosis in a Chinese Han population

Autor: Tuo Wang, Yao Sun, Zichao Xiong, Jiamin Wu, Xiaoying Ding, Xiaoye Guo, Yuan Shao

Publikováno v: BMC Cancer, Vol 21, Iss 1, Pp 1-8 (2021)

Abstract Background Astrocytoma is a common type of central nervous system tumor. In this study, we investigated the correlation between ST6GAL1 and CYP19A1 polymorphisms and the risk and prognosis of astrocytoma. Methods A total of 365 astrocytoma p

Externí odkaz: https://doaj.org/article/e2227396ff0149439b6d7c001dc471d6

A Novel Homozygous CYP19A1 Gene Mutation: Aromatase Deficiency Mimicking Congenital Adrenal Hyperplasia in an Infant without Obvious Maternal Virilisation

Autor: Fatma Dursun, Serdar Ceylaner

Publikováno v: JCRPE, Vol 11, Iss 2, Pp 196-201 (2019)

Aromatase deficiency is a rare, autosomal recessive disorder in which affected patients fail to synthesize normal estrogen. Herein, we report a 46, XX patient born with virilised external genitalia. A novel homozygous mutation in the CYP19A1 gene, ca

Externí odkaz: https://doaj.org/article/8a0d83b8060d4a34b87aa40aa6920096

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Effect of GnRH agonist before IVF on outcomes in infertile endometriosis patients: a randomized controlled trial

Autor: Ana M. Monzo, Elisabet Rodríguez-Tárrega, Patrocinio Polo-Sánchez, Edurne Novella-Maestre, Pedro J. Fernández-Colom, Ramiro Quiroga, Mercedes Monterde-Estrada, Antonio Pellicer

Publikováno v: REPRODUCTIVE BIOMEDICINE
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

Research question: Does 3-months of gonadotrophin releasing hormone agonist (GnRHa) treatment before IVF improve clinical pregnancy rate in infertile patients with endometriosis? Design: Single-blind, placebo-controlled clinical trial of 200 infertil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77ff4036e566c90582da06e9eb12260a
https://doi.org/10.1016/j.rbmo.2020.06.020

MicroRNAs and Long Noncoding RNAs as Novel Therapeutic Targets in Estrogen Receptor-Positive Breast and Ovarian Cancers

Autor: Aklank Jain, Manju Jain, Uttam Sharma, Tushar Singh Barwal, Hridayesh Prakash, Elise N. Sandberg, Ipsa Singh, Sonali Bazala, Anupam Bishayee, Shashank Shekhar

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 4072, p 4072 (2021)
International Journal of Molecular Sciences

Aromatase inhibitors (AIs) such as anastrozole, letrozole, and exemestane have shown to prevent metastasis and angiogenesis in estrogen receptor (ER)-positive breast and ovarian tumors. They function primarily by reducing estrogen production in ER-po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f81222866397cf4de083c9b7fb2d39db
https://www.mdpi.com/1422-0067/22/8/4072