Zobrazeno 1 - 10
of 1 777
pro vyhledávání: '"cyclooxygenase-2 inhibitors"'
Publikováno v:
Asian Journal of Medical Sciences, Vol 15, Iss 7, Pp 147-151 (2024)
Background: Head-and-neck squamous cell carcinoma (HNSCC) is a major cancer in India with a poor prognosis. Novel antineoplastic agents, such as selective cyclooxygenase-2 inhibitors such as celecoxib, have shown antitumor, anti-angiogenesis, and rad
Externí odkaz:
https://doaj.org/article/a4364d3f755247d0b8346622dfc5500f
Autor:
Tayanny Margarida Menezes Almeida Biase, João Gabriel Mendes Rocha, Marcus Tolentino Silva, Inês Ribeiro-Vaz, Taís Freire Galvão
Publikováno v:
Exploratory Research in Clinical and Social Pharmacy, Vol 15, Iss , Pp 100475- (2024)
Background: Selective cyclooxygenase-2 inhibitor anti-inflammatory drugs (coxibs) are associated with the development of adverse events, mainly gastrointestinal and cardiovascular, but renal effects are less known. Objective: To assess the renal risk
Externí odkaz:
https://doaj.org/article/eefa3c95c31d403ba124eb76a8c74559
Publikováno v:
Zhongguo linchuang yanjiu, Vol 36, Iss 9, Pp 1361-1365 (2023)
Objective To investigate the effect of cyclooxygenase-2 (COX-2) inhibitor parecoxib on systemic inflammatory response syndrome (SIRS) in patients with acute pancreatitis (AP). Methods A retrospective analysis was performed on 206 AP patients who were
Externí odkaz:
https://doaj.org/article/d464f076fbb7467d80b10ed4e3336e1a
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 17, Pp 919-935 (2023)
Guojin Ren,1,* Qili Zhang,1,2,* Pengfei Xia,1– 4 Jie Wang,1 Pengxia Fang,1 Xiaojie Jin,1 Xuejing Peng,1– 4 Yanli Xu,1,5 Jian Zhang,1– 4 Lei Zhao1– 5 1Gansu University of Chinese Medicine, Lanzhou, 730000, People’s Republic of China;
Externí odkaz:
https://doaj.org/article/944a06b9f13e4e27b269bb91e03ebbae
Publikováno v:
Arhiv za farmaciju, Vol 73, Iss 3, Pp 205-215 (2023)
Whereas nonselective nonsteroidal anti-inflammatory drugs, such as aspirin, ibuprofen and diclofenac, inhibit both cyclooxygenase-1 and cyclooxigenase-2 enzymes, selective inhibitors target cyclooxygenase-2, which is overexpressed in inflammation, bu
Externí odkaz:
https://doaj.org/article/2a8c6fc644604cddb9767a88fd31547b
Autor:
Mohammad Faramarzi, Sareh Roosta, Mohammad Hossein Eghbal, Bahar Nouri Rahmatabadi, Ali Faramarzi, Soliman Mohammadi‐Samani, Mahmood Shishegar, Mohammad Ali Sahmeddini
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 6, Iss 6, Pp 1307-1315 (2021)
Abstract Objective Post‐tonsillectomy pain is a common morbidity in children. The aim of this study was to compare the efficacy of celecoxib with acetaminophen on pain relief in pediatric day‐case tonsillectomy. Methods We compared the analgesic
Externí odkaz:
https://doaj.org/article/7ca242c4a1f44ff0abe0296cb870ba1f
Akademický článek
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Publikováno v:
Klinicist, Vol 14, Iss 1-2, Pp 91-99 (2020)
Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most commonly used pain relievers. However, their use often threatens with serious undesirable effects, associated mainly with damage to cardiovascular system (CVS), gastrointestinal tract, kidney
Externí odkaz:
https://doaj.org/article/85c4dcfb7a474a899f79d986ffeb358c
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Enhancing the synthesis of microbicidal and immunomodulatory host defense peptides (HDP) is a promising host-directed antimicrobial strategy to combat a growing threat of antimicrobial resistance. Here we investigated the effect of several natural cy
Externí odkaz:
https://doaj.org/article/ea70b62fce35485a8424283decf10b59
Autor:
Ina Varfaj, Alessandro Di Michele, Federica Ianni, Mario Saletti, Maurizio Anzini, Carolina Barola, Bazan Chankvetadze, Roccaldo Sardella, Andrea Carotti
Publikováno v:
Journal of Chromatography Open, Vol 1, Iss , Pp 100022- (2021)
Chiral sulfoxides represent a class of substances of great importance in many fields, including medicinal chemistry dealing with the synthesis of novel cyclooxygenase-2 (COX-2) inhibiting/NO donors. In the present study, two nitrooxyethyl sulfoxides
Externí odkaz:
https://doaj.org/article/325b0f312c5e42ba8379255c91bb1c39