Synthesis and Antiprotozoal Profile of 3,4,5‐Trisubstituted Isoxazoles

Autor: Prof. Fernanda Andreia Rosa, Samara Mendes de Souza Melo, Dr. Karlos Eduardo Pianoski, Julia Poletto, Mariellen Guilherme dosSantos, Dr. Michael Jackson Vieira da Silva, Dr. Danielle Lazarin‐Bidóia, Dr. Hélito Volpato, Prof. Sidnei Moura, Prof. Celso Vataru Nakamura

Publikováno v: ChemistryOpen, Vol 10, Iss 10, Pp 931-938 (2021)

Abstract A series of 60 4‐aminomethyl 5‐aryl‐3‐substituted isoxazoles were synthesized by an efficient method and evaluated in vitro against Leishmania amazonensis and Trypanosoma cruzi, protozoa that cause the neglected tropical diseases lei

Externí odkaz: https://doaj.org/article/239afcbf39dd485eb5b702be69eab4d1

Synthesis of New 1,3,5-Triazine-Based 2-Pyrazolines as Potential Anticancer Agents

Autor: Leydi M. Moreno, Jairo Quiroga, Rodrigo Abonia, Jonathan Ramírez-Prada, Braulio Insuasty

Publikováno v: Molecules, Vol 23, Iss 8, p 1956 (2018)

A new series of 1,3,5-triazine-containing 2-pyrazoline derivatives (8–11)a–g was synthesized by cyclocondensation reactions of [(4,6-bis((2-hydroxyethyl)amino)-1,3,5-triazin-2-yl)amine]chalcones 7a–g with hydrazine hydrate and derivatives. Chal

Externí odkaz: https://doaj.org/article/25b6fd5fa2e54a729af53fa4cd996482

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Synthesis of New 1,3,5-Triazine-Based 2-Pyrazolines as Potential Anticancer Agents

Autor: Rodrigo Abonia, Leydi M. Moreno, Braulio Insuasty, Jairo Quiroga, Jonathan Ramírez-Prada

Publikováno v: Molecules, Vol 23, Iss 8, p 1956 (2018)
Molecules
Volume 23
Issue 8
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry

A new series of 1,3,5-triazine-containing 2-pyrazoline derivatives (8&ndash
11)a&ndash
g was synthesized by cyclocondensation reactions of [(4,6-bis((2-hydroxyethyl)amino)-1,3,5-triazin-2-yl)amine]chalcones 7a&ndash
g with hydrazine hy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0def0ba508b308b0e44ba0b4de198d6c
http://www.mdpi.com/1420-3049/23/8/1956

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