Zobrazeno 1 - 10
of 2 830
pro vyhledávání: '"cyclocondensation"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 2024-2077 (2024)
Pyrazoles are rarely found in nature but are traditionally used in the agrochemical and pharmaceutical industries, while other areas of use are also actively developing. However, they have also found numerous other applications. The search for new an
Externí odkaz:
https://doaj.org/article/c4c8dfdcb1e64ce09a7f54cae8329d37
Publikováno v:
Green Chemistry Letters and Reviews, Vol 17, Iss 1 (2024)
ABSTRACTA comparative study was carried out between the methods of synthesis of C-tetra(aryl)calix[4]resorcinarenes: by means of reflux, that is to say, carrying out a cyclocondensation reaction catalyzed by hydrochloric acid between resorcinol and d
Externí odkaz:
https://doaj.org/article/693ddf61af754367901a9e3ebdd129e4
Autor:
Mikhail A. Zyryanov, Sergey O. Medvedev, Alexey A. Kukushkin, Kseniya Yu. Kuchina, Anna S. Kositsyna, Evgeny V. Root
Publikováno v:
Siberian Journal of Life Sciences and Agriculture, Vol 15, Iss 6, Pp 165-179 (2023)
Background. Wood is a unique material in its structure. However, materials made from wood raw materials have such negative properties as insufficient bio- and fire-resistance. In turn, when organizing and improving the efficiency of logging activity,
Externí odkaz:
https://doaj.org/article/20bed6782de34bc0a34f8c9272d5992d
Publikováno v:
Molecules, Vol 29, Iss 18, p 4496 (2024)
2-Chloropyridine-3-carbonitrile derivative 1 was utilized as a key precursor to build a series of linear and angular annulated pyridines linked to a 6-hydroxy-4,7-dimethoxybenzofuran moiety. Reaction of substrate 1 with various hydrazines afforded py
Externí odkaz:
https://doaj.org/article/50ffa35ac13f401ca5a29424330b437e
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 19, Iss 1, Pp 800-807 (2023)
Quinoline-based sulfonyl derivatives, and especially sulfonamides, are relevant and promising structures for drug design. We have developed a new convenient protocol for the synthesis of 3-sulfonyl-substituted quinolines (sulfonamides and sulfones).
Externí odkaz:
https://doaj.org/article/3f2caa2aad3f417ab872886a1ba98e60
Autor:
Kirill A. Gomonov, Vasilii V. Pelipko, Igor A. Litvinov, Ruslan I. Baichurin, Sergey V. Makarenko
Publikováno v:
Molbank, Vol 2024, Iss 1, p M1776 (2024)
The synthesis of previously unknown 4,5-dimethylfuro[3,4-d]pyridazin-1(2H)-one has been proposed and structurally characterized via a single-crystal X-ray diffraction analysis, 1H, 13C–{1H}, 1H–13C HMQC, and 1H–13C HMBC NMR spectroscopy, and IR
Externí odkaz:
https://doaj.org/article/cf2412243754430ea1917f0d5c23b840
Autor:
Maksim V. Dmitriev, Ekaterina E. Khramtsova, Danila Y. Apuskin, Alexander I. Andreev, Ilya I. Kovalenko, Irina V. Mashevskaya, Andrey N. Maslivets
Publikováno v:
Molbank, Vol 2024, Iss 1, p M1772 (2024)
Non-steroidal anti-inflammatory drugs (NSAIDs) are an important class of medications; however, they have some drawbacks. We are developing a new NSAID with pronounced anti-inflammatory and analgesic activities and a very low toxicity—(Z)-3-(2-oxo-2
Externí odkaz:
https://doaj.org/article/f469282d1b07466ea2450ab5a6745fd6
Autor:
I. P. Kodonidi, A. V. Bicherov, E. A. Manvelyan, A. A. Kolodina, A. A. Bicherov, M. M. Manvelyan, A. V. Ivchenko, N. N. Vdovenko-Martynova, A. T. Navalieva
Publikováno v:
Фармация и фармакология (Пятигорск), Vol 11, Iss 1, Pp 89-100 (2023)
Quinazolin-4(3Н)-one derivatives are characterized by a wide range of pharmacological properties, among which the most significant one is a pronounced effect on the central nervous system. In this regard, a molecular design of biologically active co
Externí odkaz:
https://doaj.org/article/bb209028f93e4009803ff9e16d10affe
Publikováno v:
Reactions, Vol 4, Iss 2, Pp 254-273 (2023)
The synthetic methods leading to furo[3,2-b]pyrroles and thiazolo [5,4-d]thiazoles are reviewed herein. Furo-, thieno- and seleno [3,2-b]pyrroles are related to heteropentalenes, containing two heteroatoms in the entire structure, one each per core.
Externí odkaz:
https://doaj.org/article/8a5abd423a9c46fd98bdba084426ab07
Publikováno v:
Molecules, Vol 29, Iss 10, p 2319 (2024)
The goal of this study was directed to synthesize a novel class of annulated compounds containing difuro[3,2-c:3′,2′-g]chromene. Friedländer condensation of o-aminoacetyl derivative 3 was performed with some active methylene ketones, namely, 1,3
Externí odkaz:
https://doaj.org/article/e746138c45234572896866da60b6be2c