Seasonal Single-Site Sampling Reveals Large Diversity of Marine Algal Toxins in Coastal Waters and Shellfish of New Caledonia (Southwestern Pacific)

Autor: Manoëlla Sibat, Tepoerau Mai, Simon Tanniou, Isabelle Biegala, Philipp Hess, Thierry Jauffrais

Publikováno v: Toxins, Vol 15, Iss 11, p 642 (2023)

Algal toxins pose a serious threat to human and coastal ecosystem health, even if their potential impacts are poorly documented in New Caledonia (NC). In this survey, bivalves and seawater (concentrated through passive samplers) from bays surrounding

Externí odkaz: https://doaj.org/article/c241ef22a5e64046a94a489a11f67952

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Mass Spectrometry-Based Characterization of New Spirolides from Alexandrium ostenfeldii (Dinophyceae)

Autor: Joyce A. Nieva, Jan Tebben, Urban Tillmann, Sylke Wohlrab, Bernd Krock

Publikováno v: Marine Drugs, Vol 18, Iss 10, p 505 (2020)

Spirolides belong to a group of marine phycotoxins produced by the marine planktonic dinophyte Alexandrium ostenfeldii. Composed of an imine moiety and a spiroketal ring system within a macrocylcle, spirolides are highly diverse with toxin types that

Externí odkaz: https://doaj.org/article/c38840e6899a4fcbba2567d46cc98336

Mode of action of cyclic imine toxins: 20-methyl spirolide-G antagonizes rat neuronal α3β2 nicotinic acetylcholine receptor

Autor: Gaudin, Amandine, Aráoz, Rómulo

Publikováno v: International Society for the Study of Harmful Algal Blooms., pp.205-211, 2022, 19th ICHA-Proceedings of the 19th International Conference on Harmful Algae, ⟨10.5281/zenodo.7035152⟩

Cyclic imine toxins produced by marine dinoflagellate species move up fast the food chain through shellfish and constitute a potential threat for marine wildlife and public health because of their potent antagonistic activity against nicotinic acetyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::346f00173687a57715941d9f01e6bf31
https://hal.science/hal-03876880/file/ICHA19_Proceedings_ARAOZ_2022.pdf

Cytotoxicity, Fractionation and Dereplication of Extracts of the Dinoflagellate Vulcanodinium rugosum, a Producer of Pinnatoxin G

Autor: Philipp Hess, Yves-François Pouchus, Fabienne Hervé, Véronique Séchet, Olivier Grovel, Florence Mondeguer, Yann Guitton, Valérie Fessard, Thomas Leprêtre, Gwenaëlle Desanglois, Kevin Hogeveen, Marie Geiger

Publikováno v: Marine Drugs, Vol 11, Iss 9, Pp 3350-3371 (2013)

Pinnatoxin G (PnTX-G) is a marine toxin belonging to the class of cyclic imines and produced by the dinoflagellate Vulcanodinium rugosum. In spite of its strong toxicity to mice, leading to the classification of pinnatoxins into the class of “fast-

Externí odkaz: https://doaj.org/article/1d691b9e73de48818e7fea4ef36cbbfb