Zobrazeno 1 - 10
of 3 758
pro vyhledávání: '"cx3cr1"'
Autor:
Jing Duan, Aowei Lv, Zhen Guo, Qi Liu, Chen Tian, Ying Yang, Jin Bi, Xintong Yu, Guoping Peng, Benyan Luo, Zhijian Cai, Bin Xu, Ying Fu, Jing Zhang
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-18 (2024)
Abstract In neuroinflammation, distinguishing microglia from macrophages and identifying microglial-specific biomarkers in peripheral blood pose significant challenges. This study comprehensively profiled the extracellular vesicles (EVs) of microglia
Externí odkaz:
https://doaj.org/article/d89f5cdfc7ea439d8c1d87b312be5bd5
Autor:
Kensuke Hachiya, Masahiro Masuya, Naoki Kuroda, Misao Yoneda, Komei Nishimura, Takuya Shiotani, Isao Tawara, Naoyuki Katayama
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Colorectal cancer (CRC) resulting from chronic inflammation is a crucial issue in patients with inflammatory bowel disease (IBD). Although many reports established that intestinal resident CX3CR1high macrophages play an essential role in sup
Externí odkaz:
https://doaj.org/article/d20bc050083544aca6dfded77701c377
Autor:
Lixuan Zhan, Meiqian Qiu, Jianhua Zheng, Meijing Lai, Kunqin Lin, Jiahua Dai, Weiwen Sun, En Xu
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Microglial activation-mediated neuroinflammation is a major contributor to neuronal damage after cerebral ischemia. The Fractalkine (FKN)/CX3C chemokine receptor 1 (CX3CR1) axis plays a critical role in regulating microglial activation and n
Externí odkaz:
https://doaj.org/article/da362fde034548378f4fb183292d1a3f
Autor:
Congcong Li, Zhen Zhang, Qianfeng Cai, Qitai Zhao, Han Wu, JunRu Li, Yaqing Liu, Xuan Zhao, Jinyan Liu, Yu Ping, Jiqi Shan, Shengli Yang, Yi Zhang
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Identifying tumor-relevant T cell subsets in the peripheral blood (PB) has become a potential strategy for cancer treatment. However, the subset of PB that could be used to treat cancer remains poorly defined. Here, we found that the CX3CR1+ T cell s
Externí odkaz:
https://doaj.org/article/86f7944fe50d4da3ada83ee190cde383
Autor:
Dennis-Dominik Rosmus, Jana Koch, Annika Hausmann, Aude Chiot, Franz Arnhold, Takahiro Masuda, Katrin Kierdorf, Stefanie Marie Hansen, Heidrun Kuhrt, Janine Fröba, Julian Wolf, Stefaniya Boneva, Martin Gericke, Bahareh Ajami, Marco Prinz, Clemens Lange, Peter Wieghofer
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Background The eye is a highly specialized sensory organ which encompasses the retina as a part of the central nervous system, but also non-neural compartments such as the transparent vitreous body ensuring stability of the eye globe and a c
Externí odkaz:
https://doaj.org/article/e84c464330be4cb09d23fcdd4acbbb4d
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionPrimary Sjögren syndrome (pSS) is a systemic autoimmune disease that is characterized by the infiltration of immune cells into the salivary glands. The re-establishment of salivary glands (SGs) function in pSS remains a clinical challeng
Externí odkaz:
https://doaj.org/article/4bc0ffdb18464f4caf820f64d9c2bfd4
Autor:
Aud-Malin Karlsson Hovd, Saba Nayar, Charlotte G. Smith, Premasany Kanapathippillai, Valentina Iannizzotto, Francesca Barone, Kristin Andreassen Fenton, Hege Lynum Pedersen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Tertiary lymphoid structures (TLSs) are formed in tissues targeted by chronic inflammation processes, such as infection and autoimmunity. In Sjögren’s disease, the organization of immune cells into TLS is an important part of disease progression.
Externí odkaz:
https://doaj.org/article/fc34f1ed464e4a7b92d4db6f82667450
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
IntroductionIncreasing evidence has indicated a connection between bipolar disorder (BD) and arteriosclerosis (AS), yet the specific molecular mechanisms remain unclear. This study aims to investigate the hub genes and molecular pathways for BD with
Externí odkaz:
https://doaj.org/article/1ed72a5f962f4dc181fef39d689c7d87
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
The most prevalent hip disease in neonates is developmental dysplasia of the hip (DDH). A timely and accurate diagnosis is required to provide the most effective treatment for pediatric patients with DDH. Heredity and gene variation have been the sub
Externí odkaz:
https://doaj.org/article/ff680e0d1cfc4dd0ab61ee0c6b193317
Autor:
Shaojian Lin, Yuting Dai, Changxi Han, Tianyi Han, Linfeng Zhao, Renyan Wu, Jianyue Liu, Bo Zhang, Ning Huang, Yanting Liu, Shujing Lai, Jintong Shi, Yu Wang, Meiqing Lou, Jing Xie, Yijun Cheng, Hao Tang, Hong Yao, Hai Fang, Yan Zhang, Xuefeng Wu, Lei Shen, Youqiong Ye, Li Xue, Zhe Bao Wu
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-22 (2024)
Abstract Background Pituitary neuroendocrine tumors (PitNETs) are common gland neoplasms demonstrating distinctive transcription factors. Although the role of immune cells in PitNETs has been widely recognized, the precise immunological environment a
Externí odkaz:
https://doaj.org/article/52c6217dd28941fa83eebbb4d1b0a954