Enhanced bioavailability and relative distribution of free (unconjugated) curcuminoids following the oral administration of a food-grade formulation with fenugreek dietary fibre: A randomised double-blind crossover study

Autor: Dinesh Kumar, Della Jacob, Subash PS, Abhilash Maliakkal, Johannah NM, Ramadassan Kuttan, Balu Maliakel, Veera Konda, Krishnakumar IM

Publikováno v: Journal of Functional Foods, Vol 22, Iss , Pp 578-587 (2016)

Despite the various reports on enhanced bioavailable formulations of curcumin, systemic oral bioavailability of unconjugated curcuminoids remains a challenge. Considering the differences in plasma bioactivity and membrane permeability of free curcumi

Externí odkaz: https://doaj.org/article/d58ae39762c04b19a5bb71ad9d9a1f19

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Mutual Two-Way Interactions of Curcumin and Gut Microbiota

Autor: Marzena Ułamek-Kozioł, Sławomir Januszewski, Ryszard Pluta

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1055 (2020)

Curcumin, an herbal naturally occurring polyphenol, has recently been proposed for the treatment of neurodegenerative, neurological and cancer diseases due to its pleiotropic effect. Recent studies indicated that dysbiosis is associated with the abov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f42275b974171f8469d3ba1b993a5029
https://pubmed.ncbi.nlm.nih.gov/32033441

Development of Validated Methods and Quantification of Curcuminoids and Curcumin Metabolites and Their Pharmacokinetic Study of Oral Administration of Complete Natural Turmeric Formulation (Cureit™) in Human Plasma via UPLC/ESI-Q-TOF-MS Spectrometry

Autor: Chandradhara Divya, Ajaikumar B. Kunnumakkara, Augustine Amalraj, Sreeraj Gopi, Bernd-Michael Löffler, Shintu Jude

Publikováno v: Molecules, Vol 23, Iss 10, p 2415 (2018)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules
Volume 23
Issue 10

Specific and sensitive ultra-high performance liquid chromatography-quadrupole time of flight-mass spectroscopy (UPLC-QTOF-MS) methods have been developed for the determination of curcuminoids and curcumin metabolites in human blood plasma. The UPLC-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b3250a83213a9eedb89544f633db62
https://doi.org/10.3390/molecules23102415

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