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Akademický článek

Concentrations of oocyte secreted GDF9 and BMP15 decrease with MII transition during human IVM

Autor: Jesús Cadenas, Susanne Elisabeth Pors, Ajay Kumar, Bhanu Kalra, Stine Gry Kristensen, Claus Yding Andersen, Linn Salto Mamsen

Publikováno v: Reproductive Biology and Endocrinology, Vol 20, Iss 1, Pp 1-10 (2022)

Abstract Background The suggested effects of the oocyte secreted GDF9 and BMP15 growth factors on oocyte maturation are currently based on recombinant proteins, and little is known about native GDF9 and BMP15 in humans. Methods Human immature cumulus

Externí odkaz: https://doaj.org/article/e7c5ae17be5e45ac96f9a2b0e8b37239

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Akademický článek

Interactions between serum FSH, inhibin B and antral follicle count in the decline of serum AMH during the menstrual cycle in late reproductive age

Autor: David M. Robertson, Chel Hee Lee, Angela Baerwald

Publikováno v: Endocrinology, Diabetes & Metabolism, Vol 4, Iss 2, Pp n/a-n/a (2021)

Abstract Objective To investigate the hormonal interrelationships during the menstrual cycle in women of late reproductive age with suppressed serum AMH and antral follicle count (AFC). Methods Serum hormones (AMH, FSH, LH, estradiol, progesterone, i

Externí odkaz: https://doaj.org/article/a4b26a770f34409d8514faa965e9e4b1

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Akademický článek

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Intrafollicular Concentrations of the Oocyte-secreted Factors GDF9 and BMP15 Vary Inversely in Polycystic Ovaries

Autor: Stine Gry Kristensen, Ajay Kumar, Linn Salto Mamsen, Bhanu Kalra, Susanne Elisabeth Pors, Jane Alrø Bøtkjær, Kirsten Tryde Macklon, Jens Fedder, Erik Ernst, Kate Hardy, Stephen Franks, Claus Yding Andersen

Publikováno v: E3383
E3374
Kristensen, S G, Kumar, A, Mamsen, L S, Kalra, B, Pors, S E, Bøtkjær, J A, Macklon, K T, Fedder, J, Ernst, E, Hardy, K, Franks, S & Andersen, C Y 2022, ' Intrafollicular Concentrations of the Oocyte-secreted Factors GDF9 and BMP15 Vary Inversely in Polycystic Ovaries ', The Journal of Clinical Endocrinology & Metabolism, vol. 107, no. 8, pp. e3374-e3383 . https://doi.org/10.1210/clinem/dgac272
Kristensen, S G, Kumar, A, Mamsen, L S, Kalra, B, Pors, S E, Bøtkjær, J A, Macklon, K T, Fedder, J, Ernst, E, Hardy, K, Franks, S & Andersen, C Y 2022, ' Intrafollicular Concentrations of the Oocytesecreted Factors GDF9 and BMP15 Vary Inversely in Polycystic Ovaries ', Journal of Clinical Endocrinology and Metabolism, vol. 107, no. 8, pp. E3374-E3383 . https://doi.org/10.1210/clinem/dgac272

Context The oocyte-secreted factors growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) play essential roles in follicle development and oocyte maturation, and aberrant regulation might contribute to the pathogenesis of p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b977d4cedec2e54f5ca12fcb36babf63
https://doi.org/10.1210/clinem/dgac272

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Fundamental role of BMP15 in human ovarian folliculogenesis revealed by null and missense mutations associated with primary ovarian insufficiency

Autor: Palma Finelli, Silvia Moleri, Luca Persani, Ilaria Bestetti, Ilaria Ferrari, Raffaella Rossetti, Francesco Brancati, Luisa Petrone

Publikováno v: Human Mutation. 41:983-997

Bone morphogenetic protein 15 (BMP15) encodes an oocyte factor with a relevant role for folliculogenesis as homodimer or cumulin heterodimer (BMP15-GDF9). Heterozygous BMP15 variants in the precursor or mature peptide had been associated with primary

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c61d5c7ef26416da8443f77cf2900d4
https://doi.org/10.1002/humu.23988

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Akademický článek

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Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Interactions between serum FSH, inhibin B and antral follicle count in the decline of serum AMH during the menstrual cycle in late reproductive age

Autor: David Robertson, Angela Baerwald, Chel Hee Lee

Publikováno v: Endocrinology, Diabetes & Metabolism, Vol 4, Iss 2, Pp n/a-n/a (2021)
Endocrinology, Diabetes & Metabolism

Objective To investigate the hormonal interrelationships during the menstrual cycle in women of late reproductive age with suppressed serum AMH and antral follicle count (AFC). Methods Serum hormones (AMH, FSH, LH, estradiol, progesterone, inhibin A,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d703fcc33dea58356a7d1b9f6272c7fc
https://doi.org/10.1002/edm2.172

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