Zobrazeno 1 - 10
of 2 247
pro vyhledávání: '"cucurbitacin"'
Publikováno v:
Animal Models and Experimental Medicine, Vol 7, Iss 4, Pp 397-407 (2024)
Abstract Background Restenosis frequently occurs after percutaneous angioplasty in patients with vascular occlusion and seriously threatens their health. Substantial evidence has revealed that preventing vascular smooth muscle cell proliferation usin
Externí odkaz:
https://doaj.org/article/513920945680459ab7c05ffd015bd08a
Publikováno v:
Shipin gongye ke-ji, Vol 45, Iss 8, Pp 325-335 (2024)
In order to investigate the anti-colon cancer activity of cucurbitacin B (CuB) and clarify the key role and molecular mechanism of ferroptosis in the anticancer effect of CuB. This study used human colon cancer cells HCT-116 as the model to evaluate
Externí odkaz:
https://doaj.org/article/a9512c299c274c0c8cf117e19471b1e6
Autor:
Maria Carolina Silva Marques, Nídia Cristiane Yoshida, Eduardo Caio Torres-Santos, Fernanda Rodrigues Garcez, Walmir Silva Garcez
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionLeishmaniasis, a neglected tropical parasitic disease, is regarded as a major public health problem worldwide. The first-line drugs for leishmaniasis suffer from limitations related to toxicity and the development of resistance in certain
Externí odkaz:
https://doaj.org/article/b75e1efb896c40ca89003bccab506aaa
Publikováno v:
Food Frontiers, Vol 5, Iss 1, Pp 142-159 (2024)
Abstract Colon cancer (CC) is a prevalent malignant tumor of the gastrointestinal tract and ranks among the leading causes of death in cancer patients worldwide. Cucurbitacin, a group of tetracyclic triterpenoids widely found in Cucurbitaceae plants,
Externí odkaz:
https://doaj.org/article/f613dd849d1c4b04b89fa8278d8a4475
Autor:
Anna Wallingford, Christopher Hernandez, Fathi Halaweish, Trevor Ostlund, Brent Short, Donald C. Weber
Publikováno v:
Horticulturae, Vol 10, Iss 11, p 1182 (2024)
Bitter Hawkesbury watermelon (BHW) Citrullus lanatus (Thunb.) Matsum. and Nakai (syn. Citrullus vulgaris Schad) contain high concentrations of cucurbitacin-E-glycoside (CEG), a compound that acts as an arrestant and feeding stimulant for diabroticine
Externí odkaz:
https://doaj.org/article/d43ca816eeda42dd89d4aa3914b8ec99
Autor:
Lin Wang, Hui Xu, Xin Li, Hongwei Chen, Haigang Zhang, Xunpeng Zhu, Zhijie Lin, Shilei Guo, Zhibo Bao, Haicheng Rui, Wei He, Hui Zhang
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background Osteoarthritis is a degenerative joint disease. Cartilage degeneration is the earliest and most important pathological change in osteoarthritis, and persistent inflammation is one of the driving factors of cartilage degeneration.
Externí odkaz:
https://doaj.org/article/565380b82fb94989a32d0e72246e74e5
Autor:
Xin Xu, Shiyuan Wen, Yu Zhang, Wenjing Cao, Peng Yue, Jing Kong, Meixiao Liu, Yuxin Fan, Jingjing Chen, Zhenhua Ji, Yan Dong, Guozhong Zhou, Bingxue Li, Aihua Liu, Fukai Bao
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp 376-385 (2023)
Lyme neuroborreliosis (LNB) is an infectious disease of the nervous system caused by Borrelia burgdorferi (Bb) infection. However, its pathogenesis is not fully understood. We used recombinant BmpA (rBmpA) to stimulate human microglia cell HMC3, then
Externí odkaz:
https://doaj.org/article/3627c4a41ecd4401b3b2275568e81daf
Autor:
Han-Lin Hsu, Bo-Jyun Lin, Yu-Chen Lin, Chih-Chieh Tu, Nham-Linh Nguyen, Ching-Chiung Wang, Mei-Chuan Chen, Chun-Han Chen
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 10, Pp 8138-8151 (2023)
EGFR tyrosine kinase inhibitors (TKIs) are the first-line treatment for advanced EGFR-mutated non-small-cell lung cancer (NSCLC). However, NSCLC patients with wild-type EGFR and KRAS mutation are ineligible for EGFR-TKIs. Therefore, the discovery of
Externí odkaz:
https://doaj.org/article/1d73421dea6344dab96cebadb0c59579
Autor:
Wenzhe Nie, Yalan Wang, Xinlu Tian, Jinying Liu, Zhanhui Jin, Junjie Xu, Miaohai He, Qingkun Shen, Hongyan Guo, Tian Luan
Publikováno v:
Molecules, Vol 29, Iss 17, p 4193 (2024)
The emergence of natural products has provided extremely valuable references for the treatment of various diseases. Cucurbitacin B, a tetracyclic triterpenoid compound isolated from cucurbitaceae and other plants, is the most abundant member of the c
Externí odkaz:
https://doaj.org/article/d1a414b840e84cc4a3fbd080359a0e80
Autor:
Dinglan Wu, Zhu Wang, Muqi Lin, Yi Shang, Fei Wang, JiaYi Zhou, Xiantong Zhang, Xiaomin Luo, Weiren Huang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/b9bf510e136a4ca38a5a7f530c2f1c89