Zobrazeno 1 - 10
of 113
pro vyhledávání: '"cross-species extrapolation"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
John K. Colbourne, Joseph R. Shaw, Elena Sostare, Claudia Rivetti, Romain Derelle, Rosemary Barnett, Bruno Campos, Carlie LaLone, Mark R. Viant, Geoff Hodges
Publikováno v:
Environmental Advances, Vol 9, Iss , Pp 100287- (2022)
Toxicology is traditionally divided between human and eco-toxicology. In the shared pursuit of environmental health, this separation does not account for discoveries made in the comparative studies of animal genomes. Here, we provide evidence on the
Externí odkaz:
https://doaj.org/article/c895c46d8de940a698204276b1472775
Autor:
Lars Kuepfer
Publikováno v:
SVU-International Journal of Veterinary Sciences, Vol 2, Iss 2, Pp 45-51 (2019)
The transition from experimental findings in animal models to clinical applications in human patients is a key challenge in pharmacology and toxicology. To date, this step still inhibits a significant level of uncertainty explaining amongst others
Externí odkaz:
https://doaj.org/article/a94188f39ce3415882c79a550fba59d8
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Rhomberg, Lorenz R.
Publikováno v:
Environmental Health Perspectives, 2000 May 01. 108, 343-358.
Externí odkaz:
https://www.jstor.org/stable/4619462
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Kevin R. Butt, Martin Holmstrup, David J. Spurgeon, Alice S. A. Johnston, Andreas Focks, Sabine Duquesne, Yvan Capowiez, Mathilde Zorn, Gregor Ernst, Valery E. Forbes, André Gergs, Vanessa Roeben, Cornelis A.M. van Gestel, Kim J. Rakel, Melissa Reed, Dirk Nickisch, Erik van den Berg, Joerg Roembke, Silvia Pieper, Roman Ashauer, Mark E. Hodson, Mattia Meli, Pernille Thorbek, Ralf B. Schäfer, Annika Agatz
Publikováno v:
Integrated Environmental Assessment and Management, 17(2), 352-363
Integrated Environmental Assessment and Management, 17(2), 352-363. SETAC Press
Integrated Environmental Assessment and Management
Integrated Environmental Assessment and Management, Wiley, 2021, 17 (2), pp.352-363. ⟨10.1002/ieam.4338⟩
Forbes, V E, Agatz, A, Ashauer, R, Butt, K R, Capowiez, Y, Duquesne, S, Ernst, G, Focks, A, Gergs, A, Hodson, M E, Holmstrup, M, Johnston, A S A, Meli, M, Nickisch, D, Pieper, S, Rakel, K J, Reed, M, Roembke, J, Schäfer, R B, Thorbek, P, Spurgeon, D J, Van den Berg, E, Van Gestel, C A M, Zorn, M I & Roeben, V 2021, ' Mechanistic Effect Modeling of Earthworms in the Context of Pesticide Risk Assessment : Synthesis of the FORESEE Workshop ', Integrated Environmental Assessment and Management, vol. 17, no. 2, pp. 352-363 . https://doi.org/10.1002/ieam.4338
Integrated Environmental Assessment and Management 17 (2021) 2
Integrated Environmental Assessment and Management, 17(2), 352-363. SETAC Press
Integrated Environmental Assessment and Management
Integrated Environmental Assessment and Management, Wiley, 2021, 17 (2), pp.352-363. ⟨10.1002/ieam.4338⟩
Forbes, V E, Agatz, A, Ashauer, R, Butt, K R, Capowiez, Y, Duquesne, S, Ernst, G, Focks, A, Gergs, A, Hodson, M E, Holmstrup, M, Johnston, A S A, Meli, M, Nickisch, D, Pieper, S, Rakel, K J, Reed, M, Roembke, J, Schäfer, R B, Thorbek, P, Spurgeon, D J, Van den Berg, E, Van Gestel, C A M, Zorn, M I & Roeben, V 2021, ' Mechanistic Effect Modeling of Earthworms in the Context of Pesticide Risk Assessment : Synthesis of the FORESEE Workshop ', Integrated Environmental Assessment and Management, vol. 17, no. 2, pp. 352-363 . https://doi.org/10.1002/ieam.4338
Integrated Environmental Assessment and Management 17 (2021) 2
Earthworms are important ecosystem engineers, and assessment of the risk of plant protection products toward them is part of the European environmental risk assessment (ERA). In the current ERA scheme, exposure and effects are represented simplistica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::465fd2d10dc4b99052a50b3eec5c4c4f
https://doi.org/10.1002/ieam.4338
https://doi.org/10.1002/ieam.4338
Autor:
Lina Gunnarsson, Bruno Campos, Paul L. Carmichael, Andrew White, John K. Colbourne, Geoff Hodges, Matthew P. Dent, Cecilie Rendal, Imran Shah, Carl Westmoreland, Paul Jennings, Claudia Rivetti, Steve Gutsell, Sharon J. Scott, Aude Kienzler, Ian Sorrel, Emma Butler, Luigi Margiotta-Casaluci, Fiona Sewell, Joshua A. Harrill, Richard S. Judson, Iris Muller, Stewart F. Owen, Timothy E. H. Allen, James B. Brown, Francesco Falciani, Mark R. Viant, Paul J. Russell
Publikováno v:
Toxicology in Vitro, 62:104692, 1-9. Elsevier Limited
Rivetti, C, Allen, T E H, Brown, J B, Butler, E, Carmichael, P L, Colbourne, J K, Dent, M, Falciani, F, Gunnarsson, L, Gutsell, S, Harrill, J A, Hodges, G, Jennings, P, Judson, R, Kienzler, A, Margiotta-Casaluci, L, Muller, I, Owen, S F, Rendal, C, Russell, P J, Scott, S, Sewell, F, Shah, I, Sorrel, I, Viant, M R, Westmoreland, C, White, A & Campos, B 2020, ' Vision of a near future: Bridging the human health–environment divide : Toward an integrated strategy to understand mechanisms across species for chemical safety assessment ', Toxicology in Vitro, vol. 62, 104692, pp. 1-9 . https://doi.org/10.1016/j.tiv.2019.104692
Rivetti, C, Allen, T E H, Brown, J B, Butler, E, Carmichael, P L, Colbourne, J K, Dent, M, Falciani, F, Gunnarsson, L, Gutsell, S, Harrill, J A, Hodges, G, Jennings, P, Judson, R, Kienzler, A, Margiotta-Casaluci, L, Muller, I, Owen, S F, Rendal, C, Russell, P J, Scott, S, Sewell, F, Shah, I, Sorrel, I, Viant, M R, Westmoreland, C, White, A & Campos, B 2020, ' Vision of a near future: Bridging the human health–environment divide : Toward an integrated strategy to understand mechanisms across species for chemical safety assessment ', Toxicology in Vitro, vol. 62, 104692, pp. 1-9 . https://doi.org/10.1016/j.tiv.2019.104692
There is a growing recognition that application of mechanistic approaches to understand cross-species shared molecular targets and pathway conservation in the context of hazard characterization, provide significant opportunities in risk assessment (R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4bad4785f71967ae94c513c48dac2fa
https://research.vu.nl/en/publications/e3f48638-347c-4e03-95a4-da43d64ae781
https://research.vu.nl/en/publications/e3f48638-347c-4e03-95a4-da43d64ae781