Zobrazeno 1 - 10
of 5 832
pro vyhledávání: '"cross-presentation"'
Autor:
Dandan Wan, Ziyi Bai, Yu Zhang, Li Chen, Haiying Que, Tianxia Lan, Weiqi Hong, Jiayu Huang, Cai He, Yuquan Wei, Qiang Pu, Xiawei Wei
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 10, Pp 4577-4590 (2024)
Toll-like receptor (TLR) agonists, as promising adjuvants and immunotherapeutic agents, have the potential to enhance immune responses and modulate antigen-dependent T-cell immune memory through activation of distinct signaling pathways. However, the
Externí odkaz:
https://doaj.org/article/2e21d341c48f4516bb86ba01d096d96a
Autor:
Nguyen Thi Nguyen, Xuan Thien Le, Woo Tak Lee, Yong Taik Lim, Kyung Taek Oh, Eun Seong Lee, Han-Gon Choi, Yu Seok Youn
Publikováno v:
Bioactive Materials, Vol 42, Iss , Pp 345-365 (2024)
Recently, nanovaccine-based immunotherapy has been robustly investigated due to its potential in governing the immune response and generating long-term protective immunity. However, the presentation of a tumor peptide-major histocompatibility complex
Externí odkaz:
https://doaj.org/article/13df5ecfcd1c429098a841239237a4ef
Autor:
Daping Xie, Congwei Han, Chonghao Chen, Zhencheng Liao, Senio Campos de Souza, Yiming Niu, João F. Mano, Lei Dong, Chunming Wang
Publikováno v:
Bioactive Materials, Vol 37, Iss , Pp 315-330 (2024)
Cancer vaccination holds great promise for cancer treatment, but its effectiveness is hindered by suboptimal activation of CD8+ cytotoxic T lymphocytes, which are potent effectors to mediate anti-tumor immune responses. A possible solution is to swit
Externí odkaz:
https://doaj.org/article/63cce374d08d4b5183ab56a352bb148e
Autor:
Letícia Torres-Dias, Rebeca Santana Souza, Jessica Carolina Alves Moreira, Douglas de Oliveira Paggi, Jônatas Bussador do Amaral, André Luis Lacerda Bachi, Leonardo Augusto, Marina Tiemi Shio
Publikováno v:
Immunobiology, Vol 229, Iss 5, Pp 152837- (2024)
It is known that conventional antigen presentation involves phagocytosis of antigens followed by its internalization in endocytic compartments and presentation of epitopes through MHC class II molecules for CD4 T cells. However, since 1976 a cross-pr
Externí odkaz:
https://doaj.org/article/35c0d102ea904bab95f6dc2f70017d0a
Autor:
M. Z. Saidov
Publikováno v:
Медицинская иммунология, Vol 26, Iss 3, Pp 465-502 (2024)
Proinflammatory extracellular and intracellular DAMPs are the dominant etiological factors of sterile inflammation in immuno-inflammatory rheumatic diseases. They are generated by systemic progressive disorganization of loose fibrous unformed connect
Externí odkaz:
https://doaj.org/article/f68e3d8ed44d446da3db291f126b24e5
Autor:
Francisca Borges, Raquel S. Laureano, Isaure Vanmeerbeek, Jenny Sprooten, Octavie Demeulenaere, Jannes Govaerts, Lisa Kinget, Saurabh Saraswat, Benoit Beuselinck, Steven De Vleeschouwer, Paul Clement, Frederik De Smet, Rüdiger V. Sorg, Angeliki Datsi, Nathalie Vigneron, Stefan Naulaerts, Abhishek D. Garg
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Dendritic cells (DCs) are critical players at the intersection of innate and adaptive immunity, making them ideal candidates for anticancer vaccine development. DC-based immunotherapies typically involve isolating patient-derived DCs, pulsing them wi
Externí odkaz:
https://doaj.org/article/62ea562a7fa84a7596a062de5d9f27c9
Publikováno v:
Journal of Immunotoxicology, Vol 21, Iss 1 (2024)
Molecular mimicry has been proposed to be a possible mechanism of induction of autoimmunity. In some cases, it is believed that such events could lead to a disease such as Type 1 diabetes (T1D). One of the primary MHC-I epitopes in the non-obese diab
Externí odkaz:
https://doaj.org/article/6a3de060b104403b95e15c4a0de1500a
Akademický článek
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Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Efferocytosis, the process of engulfing and removing apoptotic cells, plays an essential role in preserving tissue health and averting undue inflammation. While macrophages are primarily known for this task, dendritic cells (DCs) also play a signific
Externí odkaz:
https://doaj.org/article/a7326480197346c9904169d2846868e6