Zobrazeno 1 - 10
of 95
pro vyhledávání: '"cristina pellegrini"'
Autor:
Irene Fasciani, Francesco Petragnano, Ziming Wang, Ruairidh Edwards, Narasimha Telugu, Ilaria Pietrantoni, Ulrike Zabel, Henrik Zauber, Marlies Grieben, Maria E Terzenidou, Jacopo Di Gregorio, Cristina Pellegrini, Silvano Santini, Anna R Taddei, Bärbel Pohl, Stefano Aringhieri, Marco Carli, Gabriella Aloisi, Francesco Marampon, Eve Charlesworth, Alexandra Roman, Sebastian Diecke, Vincenzo Flati, Franco Giorgi, Fernanda Amicarelli, Andrew B Tobin, Marco Scarselli, Kostas Tokatlidis, Mario Rossi, Martin J Lohse, Paolo Annibale, Roberto Maggio
Publikováno v:
PLoS Biology, Vol 22, Iss 4, p e3002582 (2024)
Muscarinic acetylcholine receptors are prototypical G protein-coupled receptors (GPCRs), members of a large family of 7 transmembrane receptors mediating a wide variety of extracellular signals. We show here, in cultured cells and in a murine model,
Externí odkaz:
https://doaj.org/article/55337ca4f8c84555b649a08804c2bd5c
Autor:
Paolo Antonetti, Cristina Pellegrini, Chiara Caponio, Manfredo Bruni, Lorenzo Dragone, Mirco Mastrangelo, Maria Esposito, Maria Concetta Fargnoli
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 795 (2024)
Bowen’s disease represents the in situ form of cutaneous squamous cell carcinoma; although it has an excellent prognosis, 3–5% of lesions progress to invasive cutaneous squamous cell carcinoma, with a higher risk in immunocompromised patients. Tr
Externí odkaz:
https://doaj.org/article/c42693b28b0c4975bf4a675b7ae98441
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/02487a61a4ad4536b77a62b9901b67ed
Autor:
Piero Ruscitti, Maria Esposito, Ilenia Di Cola, Cristina Pellegrini, Andrea De Berardinis, Mirco Mastrangelo, Camilla Gianneramo, Antonio Barile, Maria Concetta Fargnoli, Paola Cipriani
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundThe idea of psoriatic disease continuum has been progressively prompted based on the advances of the knowledge about the pathogenic steps underpinning the occurrence of psoriasis (PSO) and psoriatic arthritis (PSA). To evaluate biomolecules
Externí odkaz:
https://doaj.org/article/f529d5a9af714d8394c4ea2fff88b7a2
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/7ad81caead5b4fce91af6ccbe2e62a40
Autor:
Lucia Di Nardo, Cristina Pellegrini, Alessandro Di Stefani, Francesco Ricci, Barbara Fossati, Laura Del Regno, Carmine Carbone, Geny Piro, Vincenzo Corbo, Pietro Delfino, Simona De Summa, Maria Giovanna Maturo, Tea Rocco, Giampaolo Tortora, Maria Concetta Fargnoli, Ketty Peris
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract A number of genes have been implicated in the pathogenesis of BCC in addition to the Hedgehog pathway, which is known to drive the initiation of this tumour. We performed in-depth analysis of 13 BCC-related genes (CSMD1, CSMD2, DPH3 promoter
Externí odkaz:
https://doaj.org/article/42184938104c4252943a7b251521a537
Autor:
Lucia Cappabianca, Veronica Zelli, Cristina Pellegrini, Michela Sebastiano, Rita Maccarone, Marco Clementi, Alessandro Chiominto, Pierdomenico Ruggeri, Ludovica Cardelli, Marianna Ruggieri, Maddalena Sbaffone, Maria-Concetta Fargnoli, Stefano Guadagni, Antonietta R. Farina, Andrew R. Mackay
Publikováno v:
Cells, Vol 12, Iss 2, p 237 (2023)
Post-therapeutic relapse, poor survival rates and increasing incidence justify the search for novel therapeutic targets and strategies in cutaneous malignant melanoma (CMM). Within this context, a potential oncogenic role for TrkA in CMM is suggested
Externí odkaz:
https://doaj.org/article/62c5e9768b1b44a98ca1d5788ab7098f
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Externí odkaz:
https://doaj.org/article/45dd952e260840699c4c5cb0d9e8129b
Autor:
Gabriella Brancaccio, Maria Concetta Fargnoli, Giulia Briatico, Cristina Pellegrini, Tea Rocco, Elvira Moscarella
Publikováno v:
Dermatology Practical & Conceptual, Vol 11, Iss S2 (2021)
Cutaneous squamous cell carcinoma (cSCC) is the second most common cancer affecting humans. The combination of the increasing incidence and high mortality in advanced stages of the disease, defines cSCC as an emerging public health problem. Advanced
Externí odkaz:
https://doaj.org/article/51ff7d12c8844339943ddee011926ee0
Autor:
Cristina Pellegrini, Ludovica Cardelli, Marina De Padova, Lucia Di Nardo, Valeria Ciciarelli, Tea Rocco, Gianluca Cipolloni, Marco Clementi, Alessio Cortellini, Alessandra Ventura, Pietro Leocata, Maria Concetta Fargnoli
Publikováno v:
Acta Dermato-Venereologica, Vol 100, Iss 1, p adv00040 (2020)
Mutations in MAPK signalling genes are driver events in melanoma, and have therapeutic relevance in the metastatic and adjuvant setting. This study evaluated the intra-patient heterogeneity of BRAF, NRAS and c-KIT mutational status between 30 primary
Externí odkaz:
https://doaj.org/article/3146c7a6086d41b3b2e0a13aab334cef