Zobrazeno 1 - 10
of 636
pro vyhledávání: '"covalently closed circular DNA"'
Autor:
Patricia Gita Naully, Marselina Irasonia Tan, Agustiningsih Agustiningsih, Caecilia Sukowati, Ernawati Arifin Giri-Rachman
Publikováno v:
Annals of Hepatology, Vol 30, Iss 1, Pp 101533- (2025)
Chronic hepatitis B virus infection (CHB) remains a global health concern, with currently available antiviral therapies demonstrating limited effectiveness in preventing hepatocellular carcinoma (HCC) development. Two primary challenges in CHB treatm
Externí odkaz:
https://doaj.org/article/6bd2f4df41414c07bbde50ddf03e04b3
Publikováno v:
Zhongguo shuxue zazhi, Vol 37, Iss 1, Pp 32-36 (2024)
Objective To analyze the detection characteristics of a novel serum marker, hepatitis B core-associated antigen (HBcrAg), in the HBsAg-/HBV DNA+ blood donors in Wuxi. Methods A total of 37 previous HBsAg-/HBV DNA+ blood donors were followed up by tel
Externí odkaz:
https://doaj.org/article/d1d0a402b6344f838a188fe3cdde3887
Autor:
Giovana Paula Angelice, Pedro Henrique Roque, Gabriel Valente, Krishna Galvão, Livia Melo Villar, Vinicius Motta Mello, Francisco C. A. Mello, Bárbara Vieira Lago
Publikováno v:
Viruses, Vol 16, Iss 11, p 1710 (2024)
Background: Despite an existing safe and effective vaccine for hepatitis B virus (HBV), it is still a major public health concern. Nowadays, several drugs are used to treat chronic hepatitis B; however, full healing remains controversial. The viral c
Externí odkaz:
https://doaj.org/article/ab19faf2a9b64da7812c7005526cc325
Autor:
Jia-Feng Wu, Chi-San Tai, Kai-Chi Chang, Ting-Wei Chen, Huey-Ling Chen, Yen-Hsuan Ni, Hong-Yuan Hsu, Mei-Hwei Chang
Publikováno v:
JHEP Reports, Vol 6, Iss 5, Pp 101061- (2024)
Background & Aim: Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) attenuates cytotoxic T lymphocyte (CTL) activation. This study was performed to examine the relationships between CTLA-4 genotypes/haplotypes, hepatitis B surface antigen (HBsAg),
Externí odkaz:
https://doaj.org/article/4fdeb274a76343099caf636b4cbba25f
Publikováno v:
Clinical and Molecular Hepatology, Vol 29, Iss 4, Pp 851-868 (2023)
The current requirement for biomarkers to detect hepatitis B virus (HBV) infection is polarized. One is a fully-automated and highly sensitive measurement system; the other is a simple system for point-of-care testing (POCT) in resource-limited areas
Externí odkaz:
https://doaj.org/article/3a36fde220dd447b8885c9d466a98452
Publikováno v:
Viruses, Vol 16, Iss 6, p 848 (2024)
Hepatitis B core-related antigen (HBcrAg) reflects the activity of intrahepatic covalently closed circular DNA. HBcrAg can be detected even in chronic hepatitis B patients in whom serum HBV DNA or hepatitis B surface antigen is undetectable. The HBcr
Externí odkaz:
https://doaj.org/article/3c7fd511f3cc47a29af7cf75002202e9
Autor:
Xiaohan Hu, Liwei Zhao, Mingrong Ou, Yuxin Chen, Hongxia Wei, Yanyan Xia, Hongpan Xu, Miao Li, Jun Wang
Publikováno v:
Heliyon, Vol 9, Iss 8, Pp e18557- (2023)
Background: Chronic hepatitis B virus (HBV) infection is one of the common infectious diseases in the world. HBV covalently closed circular DNA (cccDNA) is the initial template of HBV replication, which can exist in human hepatocytes for a long time
Externí odkaz:
https://doaj.org/article/c3a369a8acc345b5a96888fcb5a2f4c0
Publikováno v:
Microorganisms, Vol 12, Iss 3, p 599 (2024)
Chronic hepatitis B (CHB) is a global health challenge that can result in significant liver-related morbidity and mortality. Despite a prophylactic vaccine being available, patients already living with CHB often must engage in lifelong therapy with n
Externí odkaz:
https://doaj.org/article/6d186c3e667f470cb6bb23bcd961fbdd
Autor:
Lalana Garcés Marta, Ortiz Pastor Oihana, Solé Enrech Gemma, Guerra-Ruiz Armando R., Casals Mercadal Gregori, Almería Lafuente Alejandro, Ballesteros Vizoso María Antonieta, Medina Pablo Gabriel, Salgüero Fernández Sergio, Zamora Trillo Angielys, Aured de la Serna Isabel, Hurtado Juan Carlos, Pérez-Del-Pulgar Sofía, Forns Xavier, Morales Ruiz Manuel
Publikováno v:
Advances in Laboratory Medicine, Vol 3, Iss 4, Pp 321-330 (2022)
The diagnosis of hepatitis B virus (HBV) infection requires HBV DNA testing and serologic testing for detection of the surface antigen (HBsAg) and the hepatitis B core antibody (anti-HBc). There is a population of patients with occult HBV infection (
Externí odkaz:
https://doaj.org/article/ba4f1a506fb544f99cb72f4a1935a401
Publikováno v:
Viruses, Vol 15, Iss 12, p 2315 (2023)
There has been over half a century since the discovery of hepatitis B virus (HBV) to now, but approximately 300 million patients with chronic hepatitis B (CHB) still live in the world, resulting in about one million deaths every year. Although curren
Externí odkaz:
https://doaj.org/article/9861f01044054aaaaee7840f961b62ab