Zobrazeno 1 - 10
of 214
pro vyhledávání: '"copper transporters"'
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
The chronic exposure of humans to the toxic metal cadmium (Cd), either occupational or from food and air, causes various diseases, including neurodegenerative conditions, dysfunction of vital organs, and cancer. While the toxicology of Cd and its eff
Externí odkaz:
https://doaj.org/article/4b659621633641db92c27f8d81e54b4d
Autor:
Qianwen Zhao, Tonggang Qi
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Currently, cancer has become one of the major public health problems worldwide. Apoptosis is an important anti-cancer defense mechanism, which is used in the development of targeted drugs. Because cancer cells have endogenous resistance to apoptosis,
Externí odkaz:
https://doaj.org/article/1ecf9de1da514b79b46fd90dd10ba24a
Autor:
Elodie A. Pérès, Jérôme Toutain, Louis-Paul Paty, Didier Divoux, Méziane Ibazizène, Stéphane Guillouet, Louisa Barré, Aurélien Vidal, Michel Cherel, Mickaël Bourgeois, Myriam Bernaudin, Samuel Valable
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-15 (2019)
Abstract Background Diacetyl-bis(N4-methylthiosemicarbazone), labeled with 64Cu (64Cu-ATSM) has been suggested as a promising tracer for imaging hypoxia. However, various controversial studies highlighted potential pitfalls that may disable its use a
Externí odkaz:
https://doaj.org/article/e90ccfff5e35401c9889fec7302f79d4
Publikováno v:
Open Biology, Vol 11, Iss 12 (2021)
Imbalanced copper homeostasis and perturbation of membrane trafficking are two common symptoms that have been associated with the pathogenesis of neurodegenerative and neurodevelopmental diseases. Accumulating evidence from biophysical, cellular and
Externí odkaz:
https://doaj.org/article/b5a26894fbe942c19e4adf4b93d1aae0
Akademický článek
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Autor:
Amika Singla, Qing Chen, Kohei Suzuki, Jie Song, Alina Fedoseienko, Melinde Wijers, Adam Lopez, Daniel D. Billadeau, Bart van de Sluis, Ezra Burstein
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 1 (2021)
Copper is an essential transition metal for all eukaryotes. In mammals, intestinal copper absorption is mediated by the ATP7A copper transporter, whereas copper excretion occurs predominantly through the biliary route and is mediated by the paralog A
Externí odkaz:
https://doaj.org/article/ea4bf9db661d434e92aa53cbc188905f
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Copper ion homeostasis involves a finely tuned and complex multi-level response system. This study expands on various aspects of the system in the model filamentous fungus Aspergillus nidulans. An RNA-seq screen in standard growth and copper toxicity
Externí odkaz:
https://doaj.org/article/dde8c10e5c014aa08c5dae74fb1e036d
Autor:
Xin Liu, Yichen Jiang, Dan He, Xin Fang, Jianhong Xu, Yin-Won Lee, Nancy P. Keller, Jianrong Shi
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
All organisms must secure essential trace elements (e.g., Cu) for survival and reproduction. However, excess trace element accumulation in cells is highly toxic. The maintenance of copper (Cu) homeostasis has been extensively studied in mammals, bact
Externí odkaz:
https://doaj.org/article/d324806b2e9e4acc8b28b3c68aa0e04d
Akademický článek
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Akademický článek
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