Zobrazeno 1 - 10
of 150
pro vyhledávání: '"convergent functional genomics"'
Autor:
Annamaria Cattaneo, Nadia Cattane, Catia Scassellati, Ilari D’Aprile, Marco Andrea Riva, Carmine Maria Pariante
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 8, Iss , Pp 100120- (2020)
There is an overwhelming evidence proving that mental disorders are not the product of a single risk factor – i.e. genetic variants or environmental factors, including exposure to maternal perinatal mental health problems or childhood adverse event
Externí odkaz:
https://doaj.org/article/31b1b832af26487ba6b57702d165a9ec
Publikováno v:
Biomedicines, Vol 9, Iss 1525, p 1525 (2021)
Biomedicines
Volume 9
Issue 11
Biomedicines
Volume 9
Issue 11
Accumulating evidence has suggested a shared pathophysiology between Alzheimer’s disease (AD) and cardiovascular disease (CVD). Based on genome-wide transcriptomes, specifically those of blood samples, we identify the shared disease-related signatu
Autor:
Ilari D’Aprile, Nadia Cattane, Carmine M. Pariante, A. Cattaneo, Catia Scassellati, Marco A. Riva
Publikováno v:
Brain, Behavior, & Immunity-Health
Brain, Behavior, & Immunity-Health, Vol 8, Iss, Pp 100120-(2020)
Brain, Behavior, & Immunity-Health, Vol 8, Iss, Pp 100120-(2020)
There is an overwhelming evidence proving that mental disorders are not the product of a single risk factor – i.e. genetic variants or environmental factors, including exposure to maternal perinatal mental health problems or childhood adverse event
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Akademický článek
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Autor:
Malki, Karim, Tosto, Maria Grazia, Mouriño-Talín, Héctor, Rodríguez-Lorenzo, Sabela, Pain, Oliver, Jumhaboy, Irfan, Liu, Tina, Parpas, Panos, Newman, Stuart, Malykh, Arten, Carboni, Lucia, Uher, Rudolf, McGuffin, Peter, Schalkwyk, Leonard C., Bryson, Kevin, Herbster, Mark
Publikováno v:
American Journal of Medical Genetics
Response to antidepressant (AD) treatment may be a more polygenic trait than previously hypothesized, with many genetic variants interacting in yet unclear ways. In this study we used methods that can automatically learn to detect patterns of statist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1641df051babf757e7f8a2943c068d7b
https://orca.cardiff.ac.uk/id/eprint/110725/1/Malki_et_al-2017-American_Journal_of_Medical_Genetics_Part_B__Neuropsychiatric_Genetics.pdf
https://orca.cardiff.ac.uk/id/eprint/110725/1/Malki_et_al-2017-American_Journal_of_Medical_Genetics_Part_B__Neuropsychiatric_Genetics.pdf
Autor:
H Duckworth, A Ballew, Daniel R. Salomon, M Ayalew, Robert Schweitzer, Sunil M. Kurian, K Olesek, E Bellanger, N Jain, Evan A. Winiger, M Yard, S Bhosrekar, L M Gavrin, G E Sandusky, H Le-Niculescu, G Shankar, Nicholas J. Schork, L Palmer, Daniel F. Levey, J Vergo, Alexander B. Niculescu, Anantha Shekhar, M Radel
Publikováno v:
Molecular Psychiatry
Suicides are a leading cause of death in psychiatric patients, and in society at large. Developing more quantitative and objective ways (biomarkers) for predicting and tracking suicidal states would have immediate practical applications and positive
Akademický článek
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Autor:
Ayman H. Fanous, Aiden Corvin, Michael Conlon O'Donovan, A. Breier, Ming T. Tsuang, S D Patel, Helen Le-Niculescu, Evan A. Winiger, B. Changala, Daniel F. Levey, Nicholas J. Schork, Alexander B. Niculescu, M Ayalew, Mark A. Geyer, John I. Nurnberger, Daniel R. Salomon, Daniel L. Koller, Anantha Shekhar, N Jain, Richard Amdur
Publikováno v:
Molecular Psychiatry
We have used a translational convergent functional genomics (CFG) approach to identify and prioritize genes involved in schizophrenia, by gene-level integration of genome-wide association study data with other genetic and gene expression studies in h
Publikováno v:
European Neuropsychopharmacology. 20(6):357-368
We aimed to get a comprehensive insight into the genetic evidence supporting the role of GSK3 beta, in bipolar disorder (BD). Using broad searches in NCBI's PubMed and the Genetic Association Database we looked for association, whole-genome linkage,