Zobrazeno 1 - 10
of 2 107
pro vyhledávání: '"continuous manufacturing"'
Publikováno v:
EFB Bioeconomy Journal, Vol 4, Iss , Pp 100071- (2024)
The bioeconomy provides an alternative to non-renewable or fossil-based products. Biomanufacturing is emerging as a sustainable platform for the production of a wide range of value-added products, including chemicals and biodegradable materials. At p
Externí odkaz:
https://doaj.org/article/56a43a64a2a74db6b9ea98e3bf2709a0
Publikováno v:
International Journal of Pharmaceutics: X, Vol 8, Iss , Pp 100273- (2024)
Twin-screw wet granulation (TSG) is a continuous manufacturing technique either for granules as final dosage form or as an intermediate before tableting or capsule filling. A comprehensive process understanding is required to implement TSG, consideri
Externí odkaz:
https://doaj.org/article/b9981eeadcf24aeb9f8f147468933ad5
Publikováno v:
International Journal of Pharmaceutics: X, Vol 7, Iss , Pp 100242- (2024)
In continuous pharmaceutical manufacturing processes, it is crucial to control the powder flow rate. The feeding process is characterized by the amount of powder delivered per screw rotation, referred to as the feed factor. This study aims to develop
Externí odkaz:
https://doaj.org/article/b15f546fa69b4c8a8fc28175ee588722
Autor:
B. Bekaert, P.H.M. Janssen, S. Fathollahi, D. Vanderroost, T. Roelofs, B.H.J. Dickhoff, C. Vervaet, V. Vanhoorne
Publikováno v:
International Journal of Pharmaceutics: X, Vol 7, Iss , Pp 100226- (2024)
In this study, an in-depth comparison was made between batch and continuous direct compression using similar compression set-ups. The overall material processability and final tablet quality were compared and evaluated. Correlations between material
Externí odkaz:
https://doaj.org/article/4424ddfeaebc4c8eb72746b7a244416a
Publikováno v:
Engineering, Vol 32, Iss , Pp 226-232 (2024)
Vitamin B1 is widely applied in the healthcare and food industry as an antineuritic and antioxidant to maintain the normal functioning of nerve conduction, the heart, and the gastrointestinal tract. This study reports on an integrated eight-step cont
Externí odkaz:
https://doaj.org/article/83990cfc0bda47719650681a2a166565
Key Fabrications of Chitosan Nanoparticles for Effective Drug Delivery Using Flow Chemistry Reactors
Publikováno v:
International Journal of Nanomedicine, Vol Volume 18, Pp 7889-7900 (2023)
Kampanart Huanbutta,1 Pornsak Sriamornsak,2,3 Kittipat Suwanpitak,4 Nattapat Klinchuen,4 Thanapat Deebugkum,4 Vasanchai Teppitak,4 Tanikan Sangnim4 1Department of Manufacturing Pharmacy, College of Pharmacy, Rangsit University, Pathum Thani, 12000, T
Externí odkaz:
https://doaj.org/article/8288e36319ee4a84b77d60c11021108d
Publikováno v:
Pharmaceutics, Vol 16, Iss 8, p 1103 (2024)
Fiber-based technologies are widely used in various industries, but their use in pharmaceuticals remains limited. While melt extrusion is a standard method for producing medical fibers such as sutures, it is rarely used for pharmaceutical fiber-based
Externí odkaz:
https://doaj.org/article/d6e26ba513d542338cf83fb1408f0b3f
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 854 (2024)
Binder selection is a crucial step in continuous twin-screw wet granulation (TSWG), as the material experiences a much shorter residence time (2–40 s) in the granulator barrel compared to batch-wise granulation processes. Polyvinyl alcohol (PVA) 4-
Externí odkaz:
https://doaj.org/article/c0a5bb1bd8d844ee998b0f13ff919faa
Autor:
Robert M. Tona, Reeti Shah, Kimberly Middaugh, Justin Steve, João Marques, Blair R. Roszell, Cindy Jung
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 93-107 (2023)
For gene therapies to become more accessible and affordable treatment options, process intensification is one possible strategy to increase the number of doses generated per batch of viral vector. Process intensification for lentiviral vector manufac
Externí odkaz:
https://doaj.org/article/32387fd36a6540feb6dcb1faccd9a18e
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 456 (2024)
Twin-screw granulation (TSG) is an emerging continuous wet granulation technique that has not been widely applied in the industry due to a poor mechanistic understanding of the process. This study focuses on improving this mechanistic understanding b
Externí odkaz:
https://doaj.org/article/205060e1be7943718a5147ffd7793482