Zobrazeno 1 - 10
of 1 195
pro vyhledávání: '"contextual fear conditioning"'
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1711 (2024)
Background: Ceftriaxone upregulates GLT1 glutamate transporter in the brain and may have anti-CFC and anti-OCD effects. Methods: Twenty WZ-5HT rats were used to investigate the effects of ceftriaxone on obsessive–compulsive (OCD)-like behaviour in
Externí odkaz:
https://doaj.org/article/ddf1d9337d3a4ef9ae026096a42db800
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
IntroductionAnxiety and anxiety-influenced disorders are sexually dimorphic with women being disproportionately affected compared to men. Given the increased prevalence in women and the documented differences in anxiety and trauma behavior between ma
Externí odkaz:
https://doaj.org/article/532da1eb81a94e9aa8d2322004c33b71
Autor:
Ratna Sircar
Publikováno v:
Advances in Drug and Alcohol Research, Vol 3 (2023)
Objective: Earlier, we and others have reported that alcohol exposure in adolescent rat impaired performance of a spatial memory task in the Morris water maze. The goal of the present study was to investigate the effects of acute adolescent alcohol t
Externí odkaz:
https://doaj.org/article/7aeaa2ad7cd243c6904ca6add19058b9
Autor:
Noémie Eyraud, Solal Bloch, Bruno Brizard, Laurane Pena, Antoine Tharsis, Alexandre Surget, Wissam El-Hage, Catherine Belzung
Publikováno v:
Brain Sciences, Vol 14, Iss 4, p 311 (2024)
Posttraumatic stress disorder (PTSD) is a widespread fear-related psychiatric affection associated with fear extinction impairments and important avoidance behaviors. Trauma-related exposure therapy is the current first-hand treatment for PTSD, yet i
Externí odkaz:
https://doaj.org/article/179f0e937574414c9c9eb557d9a91695
Akademický článek
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Akademický článek
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Autor:
Emanuela Rizzello, Domenico Pimpinella, Annabella Pignataro, Giulia Titta, Elisabetta Merenda, Michela Saviana, Giovanni Francesco Porcheddu, Chiara Paolantoni, Francesca Malerba, Corinna Giorgi, Giulia Curia, Silvia Middei, Cristina Marchetti
Publikováno v:
Neurobiology of Disease, Vol 181, Iss , Pp 106106- (2023)
Epilepsy is a comorbidity associated with Alzheimer's disease (AD), often starting many years earlier than memory decline. Investigating this association in the early pre-symptomatic stages of AD can unveil new mechanisms of the pathology as well as
Externí odkaz:
https://doaj.org/article/59eee80ed5da48d7a674b8cffa2e0e3c
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-16 (2022)
Abstract Hippocampal CA1 parvalbumin-expressing interneurons (PV INs) play a central role in controlling principal cell activity and orchestrating network oscillations. PV INs receive excitatory inputs from CA3 Schaffer collaterals and local CA1 pyra
Externí odkaz:
https://doaj.org/article/0e90fba091844b21adecd6c7531283f1
Autor:
Sanjay Singh, Lisa Topolnik
Publikováno v:
Frontiers in Neural Circuits, Vol 17 (2023)
Fear learning and memory rely on dynamic interactions between the excitatory and inhibitory neuronal populations that make up the prefrontal cortical, amygdala, and hippocampal circuits. Whereas inhibition of excitatory principal cells (PCs) by GABAe
Externí odkaz:
https://doaj.org/article/4a2743c33b7c4d54bf51499e1095a052
Autor:
Zhiqian Yu, Mai Sakai, Hotaka Fukushima, Chiaki Ono, Yoshie Kikuchi, Ryuta Koyama, Ko Matsui, Tomoyuki Furuyashiki, Satoshi Kida, Hiroaki Tomita
Publikováno v:
Data in Brief, Vol 46, Iss , Pp 108862- (2023)
The transcription profile of microglia related to fear conditioning remains unclear. Here, we used Illumina MouseWG-6v2 microarrays to investigate the gene transcription changes in microglia and peripheral monocytes after contextual fear conditioning
Externí odkaz:
https://doaj.org/article/284da74ec2c44f1680c793ecdeefab9c