Zobrazeno 1 - 10
of 850
pro vyhledávání: '"constraint-based modeling"'
Publikováno v:
Journal of King Saud University: Computer and Information Sciences, Vol 36, Iss 6, Pp 102120- (2024)
Strain optimization aims to overproduce valuable metabolites by leveraging an understanding of biological systems, including metabolic networks and gene regulatory networks (GRNs). Accordingly, researchers proposed integrating metabolic networks and
Externí odkaz:
https://doaj.org/article/9f35b0ff72174a42bc9342e11c23b278
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Microbiomes, comprised of diverse microbial species and viruses, play pivotal roles in human health, environmental processes, and biotechnological applications and interact with each other, their environment, and hosts via ecological interactions. Ou
Externí odkaz:
https://doaj.org/article/6adcfe530c504836a88986cea2d52209
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 6 (2024)
ABSTRACT Cystic fibrosis (CF), an inherited genetic disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator gene, results in sticky and thick mucosal fluids. This environment facilitates the colonization of various mic
Externí odkaz:
https://doaj.org/article/d04d9a88b23d4e7eaea4c85ab362a6b5
Autor:
Sz-Wei Chu, Feng-Sheng Wang
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-25 (2023)
Abstract In this paper, a fuzzy hierarchical optimization framework is proposed for identifying potential antiviral targets for treating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the heart. The proposed framework compr
Externí odkaz:
https://doaj.org/article/b02546b04af84067b600a60984251bcb
Akademický článek
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Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-23 (2022)
Abstract Background Elucidating cellular metabolism led to many breakthroughs in biotechnology, synthetic biology, and health sciences. To date, deriving metabolic fluxes by 13C tracer experiments is the most prominent approach for studying metabolic
Externí odkaz:
https://doaj.org/article/15fce799bc2a45ecbbc5b262b5ea936f
Publikováno v:
Microorganisms, Vol 11, Iss 12, p 2987 (2023)
Methanotrophy is the ability of an organism to capture and utilize the greenhouse gas, methane, as a source of energy-rich carbon. Over the years, significant progress has been made in understanding of mechanisms for methane utilization, mostly in ba
Externí odkaz:
https://doaj.org/article/53ab69d243f84a2a8517b2df1d8998f2
Publikováno v:
Metabolites, Vol 13, Iss 11, p 1127 (2023)
Pathway analysis is ubiquitous in biological data analysis due to the ability to integrate small simultaneous changes in functionally related components. While pathways are often defined based on either manual curation or network topological properti
Externí odkaz:
https://doaj.org/article/7e25c32798c148ecbaabcdeb786656a0
Publikováno v:
Frontiers in Systems Biology, Vol 3 (2023)
The metabolic axis linking the gut microbiome and heart is increasingly being researched in the context of cardiovascular health. The gut microbiota-derived trimethylamine/trimethylamine N-oxide (TMA/TMAO) pathway is responsible along this axis for t
Externí odkaz:
https://doaj.org/article/aa41b194007b4fd49f888f809f7a250d
Autor:
Jan Herzog, Alexander Mook, Lotta Guhl, Miriam Bäumler, Matthias H. Beck, Dirk Weuster‐Botz, Frank R. Bengelsdorf, An‐Ping Zeng
Publikováno v:
Engineering in Life Sciences, Vol 23, Iss 1, Pp n/a-n/a (2023)
Abstract Acetobacterium woodii is known to produce mainly acetate from CO2 and H2, but the production of higher value chemicals is desired for the bioeconomy. Using chain‐elongating bacteria, synthetic co‐cultures have the potential to produce lo
Externí odkaz:
https://doaj.org/article/fcd776a761b14ec7af9577a362f93f69