Zobrazeno 1 - 10
of 92
pro vyhledávání: '"constitutive proteasome"'
Akademický článek
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Autor:
Alexander Burov, Sergei Funikov, Elmira Vagapova, Alexandra Dalina, Alexander Rezvykh, Elena Shyrokova, Timofey Lebedev, Ekaterina Grigorieva, Vladimir Popenko, Olga Leonova, Daria Spasskaya, Pavel Spirin, Vladimir Prassolov, Vadim Karpov, Alexey Morozov
Publikováno v:
Cells, Vol 10, Iss 11, p 3049 (2021)
The degradation of most intracellular proteins is a dynamic and tightly regulated process performed by proteasomes. To date, different forms of proteasomes have been identified. Currently the role of non-constitutive proteasomes (immunoproteasomes (i
Externí odkaz:
https://doaj.org/article/19082ea56f0d4d82a9b1d7c06365760f
Autor:
Alexey V. Morozov, Vadim L. Karpov
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The life of every organism is dependent on the fine-tuned mechanisms of protein synthesis and breakdown. The degradation of most intracellular proteins is performed by the ubiquitin proteasome system (UPS). Proteasomes are central elements of the UPS
Externí odkaz:
https://doaj.org/article/911665e69f6c40739a5af6841efb8f5f
Autor:
Elena Shyrokova, Sergei Funikov, Alexander Burov, Alexander P. Rezvykh, Pavel Spirin, Vadim L. Karpov, Elmira Vagapova, Vladimir S. Prassolov, T D Lebedev, Ekaterina Grigorieva, Vladimir I. Popenko, Alexandra A. Dalina, O. G. Leonova, A. V. Morozov, Daria S. Spasskaya
Publikováno v:
Cells
Cells, Vol 10, Iss 3049, p 3049 (2021)
Volume 10
Issue 11
Cells, Vol 10, Iss 3049, p 3049 (2021)
Volume 10
Issue 11
The degradation of most intracellular proteins is a dynamic and tightly regulated process performed by proteasomes. To date, different forms of proteasomes have been identified. Currently the role of non-constitutive proteasomes (immunoproteasomes (i
Autor:
Kyung Bo Kim
Publikováno v:
Cancer drug resistance (Alhambra, Calif.)
With proteasome inhibitors (PIs) becoming clinically available since 2003, outcomes for patients with multiple myeloma (MM) have dramatically changed, improving quality of life and survival. Despite the impressive treatment success, however, almost a
Autor:
El-Desoky, Ahmed H., Nehira, Tatsuo, Angkouw, Esther D., Mangindaan, Remy E.P., de Voogd, Nicole J., Hikaru, Kato, Ahmed H. , El-Desoky, Yuya, Takeishi, Tesuo, Nehira, Esther D. , Angkouw, Remy E.P. , Mangindaan, Nicole J. , de Voogd, Sachiko, Tsukamoto
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:8-10
A new halicyclamine derivative, tetradehydrohalicyclamine B (1), was isolated from the marine sponge Acanthostrongylophora ingens, along with halicyclamine B (2) as proteasome inhibitors. Compound 1 is the second example found to have a pyridinium ri
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Vadim L. Karpov, A. V. Morozov
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Frontiers in Oncology
Frontiers in Oncology
The life of every organism is dependent on the fine-tuned mechanisms of protein synthesis and breakdown. The degradation of most intracellular proteins is performed by the ubiquitin proteasome system (UPS). Proteasomes are central elements of the UPS
Autor:
Vanessa Innao, Silvana Grasso, Maria Zappalà, Roberta Ettari, Alessandro Allegra, Caterina Musolino
Publikováno v:
Pharmacologytherapeutics. 182
The ubiquitin-proteasome system (UPS) is the major non-lysosomal proteolytic system for the degradation of abnormal or damaged proteins no longer required. The proteasome is involved in degradation of numerous proteins which regulate the cell cycle,
Autor:
Nicolas Richy, Michèle Reboud-Ravaux, Naëla Janmamode, Joëlle Vidal, Xavier Maréchal, Daad Sarraf, Emilie Genin, Rémy Le Guével
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2018, 145, pp.570-587. ⟨10.1016/j.ejmech.2018.01.013⟩
European Journal of Medicinal Chemistry, 2018, 145, pp.570-587. ⟨10.1016/j.ejmech.2018.01.013⟩
European Journal of Medicinal Chemistry, Elsevier, 2018, 145, pp.570-587. ⟨10.1016/j.ejmech.2018.01.013⟩
European Journal of Medicinal Chemistry, 2018, 145, pp.570-587. ⟨10.1016/j.ejmech.2018.01.013⟩
International audience; Starting from the X-ray structure of our previous tripeptidic linear mimics of TMC-95A in complex with yeast 20S proteasome, we introduced new structural features to induce a differential inhibition between human constitutive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb14a3808b0075f834d5dec020e04418
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01713510/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01713510/document