Zobrazeno 1 - 10
of 71
pro vyhledávání: '"consomic strain"'
Autor:
Misato Kobayashi, Hironori Ueda, Naru Babaya, Michiko Itoi-Babaya, Shinsuke Noso, Tomomi Fujisawa, Fumihiko Horio, Hiroshi Ikegami
Publikováno v:
BMC Genetics, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background Both genetic and environmental factors contribute to type 2 diabetes development. We used consomic mice established from an animal type 2 diabetes model to identify susceptibility genes that contribute to type 2 diabetes developme
Externí odkaz:
https://doaj.org/article/2e6d7f5f2c5c4ad9bd2dcc728e9b01c3
Autor:
Shumpei P. Yasuda, Yuki Miyasaka, Xuehan Hou, Yo Obara, Hiroshi Shitara, Yuta Seki, Kunie Matsuoka, Ai Takahashi, Eri Wakai, Hiroshi Hibino, Toyoyuki Takada, Toshihiko Shiroishi, Ryo Kominami, Yoshiaki Kikkawa
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2221 (2022)
An MSM/Ms strain was established using Japanese wild mice, which exhibit resistance to several phenotypes associated with aging, such as obesity, inflammation, and tumorigenesis, compared to common inbred mouse strains. MSM/Ms strain is resistant to
Externí odkaz:
https://doaj.org/article/b75c825ab039479b8e28c8ba546586f6
Autor:
Fumihiko Horio, Hiroshi Ikegami, Naru Babaya, Misato Kobayashi, Hironori Ueda, Michiko Itoi-Babaya, Shinsuke Noso, Tomomi Fujisawa
Publikováno v:
BMC Genetics
BMC Genetics, Vol 21, Iss 1, Pp 1-11 (2020)
BMC Genetics, Vol 21, Iss 1, Pp 1-11 (2020)
Background Both genetic and environmental factors contribute to type 2 diabetes development. We used consomic mice established from an animal type 2 diabetes model to identify susceptibility genes that contribute to type 2 diabetes development under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff16e07891e5b3115209ac864182511
http://europepmc.org/articles/PMC7379357
http://europepmc.org/articles/PMC7379357
Akademický článek
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Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 10, Pp 3449-3457 (2017)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
Trabecular bone structure has an important influence on bone strength, but little is known about its genetic regulation. To elucidate the genetic factor(s) regulating trabecular bone structure, we compared the trabecular bone structures of two geneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49df001946d019c3615960283039b83b
https://doi.org/10.1534/g3.117.300213
https://doi.org/10.1534/g3.117.300213
Akademický článek
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Autor:
Misato Kobayashi, Tomoki Maegawa, Fumihiko Horio, Hiroshi Ikegami, Tamio Ohno, Masahide Takahashi, Naru Babaya, Yuki Miyasaka
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 29(3-4)
Streptozotocin (STZ) has been widely used to induce diabetes in rodents. Strain-dependent variation in susceptibility to STZ has been reported; however, the gene(s) responsible for STZ susceptibility has not been identified. Here, we utilized the A/J
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6de429d6201c5e32e11492ea620d64
https://pubmed.ncbi.nlm.nih.gov/29523950
https://pubmed.ncbi.nlm.nih.gov/29523950
Autor:
John R. Falck, Kevin R. Regner, Luis A. Juncos, Fan Fan, Richard J. Roman, Yoshikazu Muroya, Michael R. Garrett
Publikováno v:
Journal of the American Society of Nephrology. 26:2460-2469
Ischemia-reperfusion (IR) injury is the most common cause of AKI. The susceptibility to develop AKI varies widely among patients. However, little is known about the genes involved. 20-Hydroxyeicosatetraenoic acid (20-HETE) has an important role in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d30c7c90b7e09b919bf1f26baa884479
https://doi.org/10.1681/asn.2014090868
https://doi.org/10.1681/asn.2014090868
Akademický článek
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Autor:
Arimantas Lionikas, Mindaugas Kvedaras, Petras Minderis, Andrej Fokin, Tomas Venckunas, Aivaras Ratkevicius
Publikováno v:
Frontiers in Physiology
Phenotypic diversity between laboratory mouse strains provides a model for studying the underlying genetic mechanisms. The A/J strain performs poorly in various endurance exercise models. The aim of the study was to test if endurance capacity and con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b47cb0935cc927d04667a668aeca5c