Zobrazeno 1 - 10
of 651
pro vyhledávání: '"consensus molecular subtypes"'
Autor:
Augustin Nzitakera, Delphine Uwamariya, Hisami Kato, Jean Bosco Surwumwe, André Mbonigaba, Ella Larissa Ndoricyimpaye, Schifra Uwamungu, Felix Manirakiza, Marie Claire Ndayisaba, Gervais Ntakirutimana, Benoit Seminega, Vincent Dusabejambo, Eric Rutaganda, Placide Kamali, François Ngabonziza, Rei Ishikawa, Hirofumi Watanabe, Belson Rugwizangoga, Satoshi Baba, Hidetaka Yamada, Katsuhiro Yoshimura, Yasuhiro Sakai, Haruhiko Sugimura, Kazuya Shinmura
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Mutations in the TP53 tumor suppressor gene are well-established drivers of colorectal cancer (CRC) development. However, data on the prevalence of TP53 variants and their association with consensus molecular subtype (CMS) classif
Externí odkaz:
https://doaj.org/article/0819eb1e1b9f4228ad0b7e1b8ccc359b
Autor:
Luo Q, Quan Y, Liu W, Wu Z, Qiu W, Liang W, Yang P, Huang Q, Li G, Wei J, Wang Q, Shen F, Li W, He F, Cao J
Publikováno v:
Cancer Management and Research, Vol Volume 16, Pp 225-243 (2024)
Qingqing Luo,1,* Yibo Quan,1,* Wei Liu,1 Zixin Wu,1 Wenjing Qiu,1 Wenlong Liang,1 Ping Yang,1 Qing Huang,1 Guanwei Li,1 Jianchang Wei,1 Qiang Wang,1 Fei Shen,2 Wanglin Li,1 Feng He,3 Jie Cao1 1Department of Gastrointestinal Surgery, the Secon
Externí odkaz:
https://doaj.org/article/5ff35c95e73d42499c300457a15bea3e
Publikováno v:
Pathology and Oncology Research, Vol 30 (2024)
Introduction: Colorectal carcinomas (CRC) are one of the most frequent malignancies worldwide. Based on gene expression profile analysis, CRCs can be classified into four distinct subtypes also known as the consensus molecular subtypes (CMS), which p
Externí odkaz:
https://doaj.org/article/28612d5e236e416b86543698f5cdb166
Autor:
Ioannis A. Voutsadakis
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 11, Pp 8670-8686 (2023)
Metastatic colon cancer remains incurable despite improvements in survival outcomes. New therapies based on the discovery of colon cancer genomic subsets could improve outcomes. Colon cancers from genomic studies with publicly available data were exa
Externí odkaz:
https://doaj.org/article/7d2f3845c1a94094a084d631b0229cc4
Akademický článek
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Autor:
Jean Bastin, Marine Sroussi, Ivan Nemazanyy, Pierre Laurent-Puig, Sophie Mouillet-Richard, Fatima Djouadi
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Colorectal cancer (CRC) can be classified into four molecular subtypes (CMS) among which CMS1 is associated with the best prognosis, while CMS4, the mesenchymal subtype, has the worst outcome. Although mitochondria are considered
Externí odkaz:
https://doaj.org/article/08da4395fe2b4e27ba67cb17740e7c9b
Autor:
Ronja S. Adam, Dennis Poel, Leandro Ferreira Moreno, Joey M. A. Spronck, Tim R. deBack, Arezo Torang, Patricia M. Gomez Barila, Sanne tenHoorn, Florian Markowetz, Xin Wang, Henk M. W. Verheul, Tineke E. Buffart, Louis Vermeulen
Publikováno v:
Molecular Oncology, Vol 16, Iss 14, Pp 2693-2709 (2022)
Previously, colorectal cancer (CRC) has been classified into four distinct molecular subtypes based on transcriptome data. These consensus molecular subtypes (CMSs) have implications for our understanding of tumor heterogeneity and the prognosis of p
Externí odkaz:
https://doaj.org/article/67372eeed1f24b6089c25d30995100a1
Autor:
Inge van denBerg, Marcel Smid, Robert R. J. Coebergh van den Braak, Mark A. van deWiel, Carolien H. M. vanDeurzen, Vanja deWeerd, John W. M. Martens, Jan N. M. IJzermans, Saskia M. Wilting
Publikováno v:
Molecular Oncology, Vol 15, Iss 12, Pp 3348-3362 (2021)
Consensus molecular subtypes (CMSs) can guide precision treatment of colorectal cancer (CRC). We aim to identify methylation markers to distinguish between CMS2 and CMS3 in patients with CRC, for which an easy test is currently lacking. To this aim,
Externí odkaz:
https://doaj.org/article/00cc8da0246e4a18907d6f294fb0eba1
Akademický článek
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Akademický článek
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