Zobrazeno 1 - 10
of 28
pro vyhledávání: '"conditional targeting"'
Autor:
JeongGoo Lee, Martin Heur
Publikováno v:
Taiwan Journal of Ophthalmology, Vol 13, Iss 1, Pp 28-33 (2023)
PURPOSE: The inducible Cre-ERT2 recombinase system allows for temporal control of gene targeting, and it is useful to studying adult function of genes that have critical developmental roles. The Zeb1flox/flox: UBC-CreERT2 mouse was generated to condi
Externí odkaz:
https://doaj.org/article/63b6088d4ea74e648b10fc60d869971c
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 5, Iss C, Pp 51-58 (2017)
Human pluripotent stem cells (hPSCs) are a promising source of regenerative material for clinical applications. However, hPSC transplant therapies pose the risk of teratoma formation and malignant transformation of undifferentiated remnants. These pr
Externí odkaz:
https://doaj.org/article/f9dd65cb92f846ed9819b2dd77b341f2
Akademický článek
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Autor:
Yohei eKobayashi, Takao K. Hensch
Publikováno v:
Frontiers in Neural Circuits, Vol 7 (2013)
Externí odkaz:
https://doaj.org/article/69cea3f28c614b96b10df3b8c5ef0fab
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 5, Iss C, Pp 51-58 (2017)
Molecular Therapy: Methods & Clinical Development, Vol 5, Iss C, Pp 51-58 (2017)
Human pluripotent stem cells (hPSCs) are a promising source of regenerative material for clinical applications. However, hPSC transplant therapies pose the risk of teratoma formation and malignant transformation of undifferentiated remnants. These pr
Publikováno v:
Journal of Diabetes Investigation
Diabetic nephropathy is the major cause of end-stage renal failure throughout the world in both developed and developing countries. Diabetes affects all cell types of the kidney, including endothelial cells, tubulointerstitial cells, podocytes and me
Publikováno v:
Methods in molecular biology. 920:39-49
The chicken B cell line DT40 has been widely used as a model system for reverse genetics studies in higher eukaryotes, because of its advantages including efficient gene targeting and ease of chromosome manipulation. Although the genetic approach usi
Publikováno v:
新潟医学会雑誌. 116(10):482-492
The hippocampal CA 3 region is thought to be an important place for formation of learning and memory. To understand the role of the hippocampal CA 3 region in the higher brain functions, we attempted to make a conditional targeting system specific fo
Autor:
Takao K. Hensch, Yohei Kobayashi
Publikováno v:
Frontiers in Neural Circuits, Vol 7 (2013)
Frontiers in Neural Circuits
Frontiers in Neural Circuits
Conditional gene targeting allows us to study gene function in specific tissues or cell types. This is commonly achieved by Cre DNA recombinase and its 34–base pair target sequences called loxP sites. Through the efforts of individual labs and larg
Autor:
Jeanguenin, Linda, Alcon, Carine, Duby, Geoffrey, Boeglin, Martin, Chérel, Isabelle, Gaillard, Isabelle, Zimmermann, Sabine, Sentenac, Hervé, Véry, Anne-Aliénor
Publikováno v:
Plant Journal
Plant Journal, Wiley, 2011, 67 (4), pp.570-82. ⟨10.1111/j.1365-313X.2011.04617.x⟩
Plant Journal, Wiley, 2011, 67 (4), pp.570-82. ⟨10.1111/j.1365-313X.2011.04617.x⟩
International audience; A functional Shaker potassium channel requires assembly of four α-subunits encoded by a single gene or various genes from the Shaker family. In Arabidopsis thaliana, AtKC1, a Shaker α-subunit that is silent when expressed al