Generation of Conditional KO Mice of CCN2 and Its Function in the Kidney.

Autor: Yokoi H; Department of Nephrology, Graduate School of Medicine, Kyoto University, Kyoto, Japan. yokoih@kuhp.kyoto-u.ac.jp., Toda N; Department of Nephrology, Kansai Electric Power Hospital, Osaka, Japan.; Department of Nephrology, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan., Mukoyama M; Department of Nephrology, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2023; Vol. 2582, pp. 391-409.

Generation of Conditional KO Mice of CCN2 and Its Function in the Kidney

Autor: Hideki, Yokoi, Naohiro, Toda, Masashi, Mukoyama

Publikováno v: Methods in molecular biology (Clifton, N.J.). 2582

CCN2 has been shown to be closely involved in the progression of renal fibrosis, indicating the potential of CCN2 inhibition as a therapeutic target. Although the examination of the renal disease phenotypes of adult CCN2 knockout mice has yielded val

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cebb29d0b93dc050572d0301f34f89c8
https://pubmed.ncbi.nlm.nih.gov/36370365

Tyrosine hydroxylase conditional KO mice reveal peripheral tissue-dependent differences in dopamine biosynthetic pathways.

Autor: Katsuya Miyajima¹, Chiaki Kawamoto¹, Satoshi Hara¹, Masayo Mori-Kojima¹, Tamae Ohye², Chiho Sumi-Ichinose³, Nae Saito^4,5, Toshikuni Sasaoka⁴, Daniel Metzger⁶, Hiroshi Ichinose¹ hichinos@bio.titech.ac.jp

Publikováno v: Journal of Biological Chemistry. Jan-Jun2021, Vol. 296, p1-12. 12p.

Tyrosine hydroxylase conditional KO mice reveal peripheral tissue-dependent differences in dopamine biosynthetic pathways

Autor: Masayo Mori-Kojima, Chiaki Kawamoto, Satoshi Hara, Daniel Metzger, Katsuya Miyajima, Chiho Sumi-Ichinose, Tamae Ohye, Toshikuni Sasaoka, Hiroshi Ichinose, Nae Saito

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2021, 296, pp.100544. ⟨10.1016/j.jbc.2021.100544⟩
The Journal of Biological Chemistry

Dopamine (DA) exerts well-known functions in the brain as a neurotransmitter. In addition, it plays important physiological roles in peripheral organs, but it is largely unknown how and where peripheral DA is synthesized and regulated. Catecholamines

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc82740686aefef1da6e4fb1ac3ccb2
https://doi.org/10.1016/j.jbc.2021.100544

Effects of NPY/1R deletion in the limbic area on behavior, reproduction and stress response in conditional KO mice, relating to early maternal environment

Autor: Marrazzo, Alessandro

Il fenotipo è il complesso di caratteristiche risultanti dall’interazione tra geni e ambiente. I geni influiscono sulla formazione di un individuo, che mostrerà o meno determinate caratteristiche. Il ruolo dell’ambiente è anch’esso di fondam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______341::7a5ed2267cc63b4b2e5847b38744ec52
http://hdl.handle.net/1889/3633