CADEE: Computer-Aided Directed Evolution of Enzymes

Autor: Beat Anton Amrein, Fabian Steffen-Munsberg, Ireneusz Szeler, Miha Purg, Yashraj Kulkarni, Shina Caroline Lynn Kamerlin

Publikováno v: IUCrJ, Vol 4, Iss 1, Pp 50-64 (2017)

The tremendous interest in enzymes as biocatalysts has led to extensive work in enzyme engineering, as well as associated methodology development. Here, a new framework for computer-aided directed evolution of enzymes (CADEE) is presented which allow

Externí odkaz: https://doaj.org/article/1d624775a53c4aa78b73074d83ceb136

CADEE: Computer-Aided Directed Evolution of Enzymes

Autor: Miha Purg, Ireneusz Szeler, Beat Anton Amrein, Shina Caroline Lynn Kamerlin, Fabian Steffen-Munsberg, Yashraj Kulkarni

Publikováno v: IUCrJ
IUCrJ, Vol 4, Iss 1, Pp 50-64 (2017)

A new computational tool, CADEE (Computer-Aided Directed Evolution of Enzymes), is presented.
The tremendous interest in enzymes as biocatalysts has led to extensive work in enzyme engineering, as well as associated methodology development. Here

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145987c9898df35607f08aafcaf9aaa7
http://europepmc.org/articles/PMC5331465

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Speeding up enzyme engineering computationally.

Autor: Scrutton NS; Synthetic Biology Research Centre for Fine and Speciality Chemicals, Manchester Institute of Biotechnology and School of Chemistry, The University of Manchester, Manchester Institute of Biotechnology , 131 Princess Street, Manchester M1 7DN, UK.

Publikováno v: IUCrJ [IUCrJ] 2016 Dec 24; Vol. 4 (Pt 1), pp. 5-6. Date of Electronic Publication: 2016 Dec 24 (Print Publication: 2017).