Zobrazeno 1 - 10
of 869
pro vyhledávání: '"comprehensive genomic profiling"'
Autor:
Genevieve Dall, Karen Harris, Nonie Chan, Stephen J. Luen, Sophia Frentzas, Daphne Day, Michelle Barrett, Anna Kilgour, Mark Buzza
Publikováno v:
Current Oncology, Vol 31, Iss 8, Pp 4519-4530 (2024)
The Victorian Precision Oncology Summit, convened in 2023, was a joint initiative between the Victorian Comprehensive Cancer Centre Alliance (VCCC Alliance) and the Monash Partners Comprehensive Cancer Consortium (MPCCC) and was proposed to guide a c
Externí odkaz:
https://doaj.org/article/925a83d307a64d109d6bb755f122a7ca
Autor:
Jiayin Dong, Jing Ni, Jiahui Chen, Xuening Wang, Luxin Ye, Xia Xu, Wenwen Guo, Xiaoxiang Chen
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-11 (2024)
Abstract Purpose Ovarian cancer (OC) is characterized by a high recurrence rate, and homologous recombination deficiency (HRD) is an important biomarker in the clinical management of OC. We investigated the differences in clinical genomic profiles be
Externí odkaz:
https://doaj.org/article/a9eeb241b2574d93a2709661d4fdb479
Publikováno v:
Thoracic Cancer, Vol 15, Iss 18, Pp 1454-1456 (2024)
Abstract Although dabrafenib plus trametinib has been approved for BRAF V600E mutation positive advanced non‐small cell lung cancer (NSCLC), data on its efficacy against uncommon BRAF mutations are still limited due to their rare frequency. We repo
Externí odkaz:
https://doaj.org/article/8304f5f801794ef8a5a47c81e64fabd0
Autor:
Mary K. Nesline, Vivek Subbiah, Rebecca A. Previs, Kyle C. Strickland, Heidi Ko, Paul DePietro, Michael D. Biorn, Maureen Cooper, Nini Wu, Jeffrey Conroy, Sarabjot Pabla, Shengle Zhang, Zachary D. Wallen, Pratheesh Sathyan, Kamal Saini, Marcia Eisenberg, Brian Caveney, Eric A. Severson, Shakti Ramkissoon
Publikováno v:
Oncology and Therapy, Vol 12, Iss 2, Pp 329-343 (2024)
Abstract Introduction Tissue-based broad molecular profiling of guideline-recommended biomarkers is advised for the therapeutic management of patients with non-small cell lung cancer (NSCLC). However, practice variation can affect whether all indicat
Externí odkaz:
https://doaj.org/article/faa519bba6084d7cb86ca6ab28c54740
Autor:
Stephanie Snow, Christine Brezden-Masley, Michael D. Carter, Neesha Dhani, Cassandra Macaulay, Ravi Ramjeesingh, Michael J. Raphael, Monika Slovinec D’Angelo, Filomena Servidio-Italiano
Publikováno v:
Current Oncology, Vol 31, Iss 3, Pp 1359-1375 (2024)
Genomic medicine is a powerful tool to improve diagnosis and outcomes for cancer patients by facilitating the delivery of the right drug at the right dose at the right time for the right patient. In 2023, a Canadian conference brought together leader
Externí odkaz:
https://doaj.org/article/317a704106c04acd9e864441830b5a9e
Autor:
Kabsoo Shin, Ryul Kim, Hansol Park, Wonchul Lee, Sangmoon Lee, Joonoh Im, Ji Eun Lee, Sung Hun Kim, Erin Connolly-Strong, Young Seok Ju, Brian Baek-Lok Oh, Jeongmin Lee
Publikováno v:
Case Reports in Oncology, Vol 17, Iss 1, Pp 317-328 (2024)
Introduction: Breast cancer exhibits vast genomic diversity, leading to varied clinical manifestations. Integrating molecular subtyping with in-depth genomic profiling is pivotal for informed treatment choices and prognostic insights. Whole-genome cl
Externí odkaz:
https://doaj.org/article/163cc040afc14e8e844eef650b620015
Autor:
Matteo Pallocca, Ivan Molineris, Enrico Berrino, Benedetta Marcozzi, Martina Betti, Lauretta Levati, Stefania D’Atri, Chiara Menin, Gabriele Madonna, Paola Ghiorzo, Jenny Bulgarelli, Virgina Ferraresi, Tiziana Venesio, Monica Rodolfo, Licia Rivoltini, Luisa Lanfrancone, Paolo Antonio Ascierto, Luca Mazzarella, Pier Giuseppe Pelicci, Ruggero De Maria, Gennaro Ciliberto, Enzo Medico, Giandomenico Russo
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-7 (2024)
Abstract Background The current therapeutic algorithm for Advanced Stage Melanoma comprises of alternating lines of Targeted and Immuno-therapy, mostly via Immune-Checkpoint blockade. While Comprehensive Genomic Profiling of solid tumours has been ap
Externí odkaz:
https://doaj.org/article/aa5718450c4648a7bae3716959838906
Autor:
Mirai Ido, Kimihito Fujii, Hideyuki Mishima, Akihito Kubo, Masayuki Saito, Hirona Banno, Yukie Ito, Manami Goto, Takahito Ando, Yukako Mouri, Junko Kousaka, Tsuneo Imai, Shogo Nakano
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Aim The aim of this study was to investigate genetic alterations within breast cancer in the setting of recurrent or de novo stage IV disease. Patients and methods : This study included 22 patients with recurrent breast cancer (n = 19) and i
Externí odkaz:
https://doaj.org/article/34d366c9102448fa859ba2a262a2204e
Autor:
Shang‐Hung Chen, Ka‐Po Tse, Yen‐Jung Lu, Shu‐Jen Chen, Yu‐Feng Tian, Kien Thiam Tan, Chien‐Feng Li
Publikováno v:
Cancer Medicine, Vol 13, Iss 12, Pp n/a-n/a (2024)
Abstract Background Breast cancer is a heterogeneous disease categorized based on molecular characteristics, including hormone receptor (HR) and human epidermal growth factor receptor 2 (HER2) expression levels. The emergence of profiling technology
Externí odkaz:
https://doaj.org/article/556eec84f6ec4018be34d1e7a502c792
Publikováno v:
Cancer Medicine, Vol 13, Iss 12, Pp n/a-n/a (2024)
Abstract Background Members of the neurotrophic tropomyosin receptor kinase (NTRK) gene family, NTRK1, NTRK2, and NTRK3 encode TRK receptor tyrosine kinases. Intra‐ or inter‐chromosomal gene rearrangements produce NTRK gene fusions encoding fusio
Externí odkaz:
https://doaj.org/article/0c4e6c216d3d4e609290f7e2ce658c5f