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pro vyhledávání: '"complex disease"'
Autor:
Lalagkas, Panagiotis N.1 (AUTHOR), Melamed, Rachel D.1 (AUTHOR) Rachel_Melamed@uml.edu
Publikováno v:
BMC Medical Genomics. 9/10/2024, Vol. 17 Issue 1, p1-11. 11p.
Autor:
Castro-Prado, Fernando
[PhD thesis of FCP.] Nowadays, genetics studies large amounts of very diverse variables. Mathematical statistics has evolved in parallel to its applications, with much recent interest high-dimensional settings. In the genetics of human common disease
Externí odkaz:
http://arxiv.org/abs/2407.19624
Autor:
Hamed, Ahmed Abdeen, Fandy, Tamer E.
The objective of this research is to introduce a network specialized in predicting drugs that can be repurposed by investigating real-world evidence sources, such as clinical trials and biomedical literature. Specifically, it aims to generate drug co
Externí odkaz:
http://arxiv.org/abs/2406.13106
Akademický článek
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Autor:
Trottet, Cécile, Schürch, Manuel, Allam, Ahmed, Barua, Imon, Petelytska, Liubov, Distler, Oliver, Hoffmann-Vold, Anna-Maria, Krauthammer, Michael, collaborators, the EUSTAR
In this paper, we propose a deep generative time series approach using latent temporal processes for modeling and holistically analyzing complex disease trajectories. We aim to find meaningful temporal latent representations of an underlying generati
Externí odkaz:
http://arxiv.org/abs/2311.08149
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-11 (2024)
Abstract Background Drugs targeting disease causal genes are more likely to succeed for that disease. However, complex disease causal genes are not always clear. In contrast, Mendelian disease causal genes are well-known and druggable. Here, we seek
Externí odkaz:
https://doaj.org/article/778716eddc6d422cb7f374abc954f1e5
Autor:
Priya, Tahmina Sultana, Leng, Fan, Luehrs, Anthony C., Klee, Eric W., Allen, Alina M., Lazaridis, Konstantinos N., Danfeng, Yao, Tian, Shulan
Non-alcoholic fatty liver disease (NAFLD) is a prevalent chronic liver disorder characterized by the excessive accumulation of fat in the liver in individuals who do not consume significant amounts of alcohol, including risk factors like obesity, ins
Externí odkaz:
http://arxiv.org/abs/2311.08428