Zobrazeno 1 - 10
of 124
pro vyhledávání: '"complement therapeutics"'
Publikováno v:
Exploration of Immunology, Vol 4, Iss 5, Pp 577-615 (2024)
Complement is both evolutionary and scientifically old. It predates the adaptive immunity by some 600 million years and was first described in 1905 by Jules Bordet and Paul Ehrlich. For the most of its, the existence complement system has been ignore
Externí odkaz:
https://doaj.org/article/d960d2e9f48249b4adb31d88b480549f
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Anti-glomerular basement membrane (GBM) disease is a rare but life-threatening autoimmune disorder characterized by rapidly progressive glomerulonephritis with or without pulmonary hemorrhage. Renal biopsies of anti-GBM patients predominantly show li
Externí odkaz:
https://doaj.org/article/4a49fad99acf4b70a804e3229655b735
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1473-1486 (2023)
Human complement is the first line of defence against invading pathogens and is involved in tissue homeostasis. Complement-targeted therapies to treat several diseases caused by a dysregulated complement are highly desirable. Despite huge efforts inv
Externí odkaz:
https://doaj.org/article/1cb2749bacb5487f8b7c32eb72d5cf63
Autor:
Youssif M. Ali, Nicholas J. Lynch, Ahmed A. Shaaban, Dina E. Rizk, Shaymaa H. Abdel-Rahman, Priyanka Khatri, Munehisa Yabuki, Sadam Yaseen, Thomas Dudler, Gregory Demopulos, Wilhelm J. Schwaeble
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Acute respiratory distress syndrome (ARDS) is a life-threatening disorder with a high rate of mortality. Complement activation in ARDS initiates a robust inflammatory reaction that can cause progressive endothelial injury in the lung. Here, we tested
Externí odkaz:
https://doaj.org/article/892bed69f9b0470381a042c2abcca0b3
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/49a970844e7542419c9be50b12e360c2
Akademický článek
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Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The complement system is an important part of the innate immune system, providing a strong defense against pathogens and removing apoptotic cells and immune complexes. Due to its strength, it is important that healthy human cells are protected agains
Externí odkaz:
https://doaj.org/article/d03dd475e7ff455987e44f3a99cbdc4e
Autor:
Judith E. van Zanden, Neeltina M. Jager, Mohamed R. Daha, Michiel E. Erasmus, Henri G. D. Leuvenink, Marc A. Seelen
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Over the last decade, striking progress has been made in the field of organ transplantation, such as better surgical expertise and preservation techniques. Therefore, organ transplantation is nowadays considered a successful treatment in end-stage di
Externí odkaz:
https://doaj.org/article/090b70106ddd4288a16d68cc8a498ffb
Autor:
Ali, Youssif M, Lynch, Nicholas J, Shaaban, Ahmed A, Rizk, Dina E, Abdel-Rahman, Shaymaa H, Khatri, Priyanka, Yabuki, Munehisa, Yaseen, Sadam, Dudler, Thomas, Demopulos, Gregory, Schwaeble, Wilhelm J
Acute respiratory distress syndrome (ARDS) is a life-threatening disorder with a high rate of mortality. Complement activation in ARDS initiates a robust inflammatory reaction that can cause progressive endothelial injury in the lung. Here, we tested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______109::0fe05f51372be4943361e10c7216f512
https://www.repository.cam.ac.uk/handle/1810/350921
https://www.repository.cam.ac.uk/handle/1810/350921
Autor:
Seline A. Zwarthoff, Evelien T. M. Berends, Sanne Mol, Maartje Ruyken, Piet C. Aerts, Mihály Józsi, Carla J. C. de Haas, Suzan H. M. Rooijakkers, Ronald D. Gorham
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Complement is essential for the protection against infections; however, dysregulation of complement activation can cause onset and progression of numerous inflammatory diseases. Convertase enzymes play a central role in complement activation and prod
Externí odkaz:
https://doaj.org/article/8a79aad178284ea5b868090d493beb6b