Age-related macular degeneration: a disease of systemic or local complement dysregulation?

Autor: Samir Khandhadia, Alasdair Warwick, Andrew J. Lotery, Sarah Ennis

Publikováno v: Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 3, Iss 4, Pp 1234-1257 (2014)

Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in developed countries. The role of complement in the development of AMD is now well-established. While some studies show evidence of complement dysregulation withi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::389127267ede0a278b9651680319d125
https://eprints.soton.ac.uk/390431/

Expression of complement components coincides with early patterning and organogenesis in Xenopus laevis

Autor: Valérie Anne Mclin, Cheng-Hui Hu, Milan Jamrich, Rina Shah

Publikováno v: International Journal of Developmental Biology, Vol. 52, No 8 (2008) pp. 1123-1133

The complement system is the central component of innate immunity and an important player in the adaptive immunity of vertebrates. We analyzed the expression patterns of several key members of the complement cascade during Xenopus development. We fou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebf9e78816e6dad563d771f40f52a1c2
https://archive-ouverte.unige.ch/unige:19625

Ligand binding properties of the very low density lipoprotein receptor. Absence of the third complement-type repeat encoded by exon 4 is associated with reduced binding of Mr 40,000 receptor-associated protein

Autor: Rettenberger, P. M., Oka, K., Ellgaard, L., Petersen, H. H., Christensen, A., Pia Møller Martensen, Monard, D., Etzerodt, M., Chan, L., Andreasen, P. A.

Publikováno v: Rettenberger, P M, Oka, K, Ellgaard, L, Petersen, H H, Christensen, A, Martensen, P M, Monard, D, Etzerodt, M, Chan, L & Andreasen, P A 1999, ' Ligand binding properties of the very low density lipoprotein receptor. Absence of the third complement-type repeat encoded by exon 4 is associated with reduced binding of Mr 40,000 receptor-associated protein ', Journal of Biological Chemistry, vol. 274, no. 13, pp. 8973-80 .
Aarhus University

The very low density lipoprotein receptor (VLDLR) binds, among other ligands, the Mr 40,000 receptor-associated protein (RAP) and a variety of serine proteinase-serpin complexes, including complexes of the proteinase urokinase-type plasminogen activa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8a540aae7937df2c1609ea445d00c428
https://pure.au.dk/portal/da/publications/ligand-binding-properties-of-the-very-low-density-lipoprotein-receptor-absence-of-the-third-complementtype-repeat-encoded-by-exon-4-is-associated-with-reduced-binding-of-mr-40000-receptorassociated-protein(9ee050a6-4813-4a6e-b7f4-d28eee8506d0).html

Genska analiza sustava komplementa u odraslih pacijenata s elementima trombotične mikroangiopatije – prikaz serije slučajeva. (Croatian)

Autor: Kasumović, Dino, Zagorec, Nikola, Tišljar, Miroslav, Horvatić, Ivica, Šenjug, Petar, Ljubanović, Danica Galešić, Galešić, Krešimir

Publikováno v: Lijecnicki Vjesnik; 2024, Vol. 146 Issue 7/8, p291-298, 8p

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