Zobrazeno 1 - 10
of 78
pro vyhledávání: '"complement system activation"'
Akademický článek
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Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Thrombotic microangiopathies (TMA) constitute a group of different disorders that have a common underlying mechanism: the endothelial damage. These disorders may exhibit different mechanisms of endothelial injury depending on the pathological trigger
Externí odkaz:
https://doaj.org/article/dc7d3584852940869e82f90547182914
Autor:
Cathryn M. Kolka, Julie Webster, Ailin Lepletier, Clay Winterford, Ian Brown, Renee S. Richards, Wioleta M. Zelek, Yilang Cao, Ramlah Khamis, Karthik B. Shanmugasundaram, Alain Wuethrich, Matt Trau, Sandra Brosda, Andrew Barbour, Alok K. Shah, Guy D. Eslick, Nicholas J. Clemons, B. Paul Morgan, Michelle M. Hill
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The early complement components have emerged as mediators of pro-oncogenic inflammation, classically inferred to cause terminal complement activation, but there are limited data on the activity of terminal complement in cancer. We previously reported
Externí odkaz:
https://doaj.org/article/7a5670f9f3814e8daeeeb4ffc389c13c
Autor:
Amelie Kuhn, Jana Riegger, Graciosa Q. Teixeira, Markus Huber-Lang, John D. Lambris, Cornelia Neidlinger-Wilke, Rolf E. Brenner
Publikováno v:
Cells, Vol 12, Iss 6, p 887 (2023)
Terminal complement complex (TCC) deposition was identified in human degenerated discs. To clarify the role of terminal complement activation in disc degeneration (DD), we investigated respective activating mechanisms and cellular effects in annulus
Externí odkaz:
https://doaj.org/article/503a1bd248494d9096c65bd6142d786d
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Thrombotic microangiopathy is a rare but serious complication that affects kidney transplant recipients. It appears in 0.8–14% of transplanted patients and negatively affects graft and patient survival. It can appear in a systemic form, with hemoly
Externí odkaz:
https://doaj.org/article/60cd872124c24a6ba19aa795a36ffafa
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Deposits of complement components have been documented in several human tumors suggesting a potential involvement of the complement system in tumor immune surveillance. In vitro and in vivo studies have revealed a double role played by this system in
Externí odkaz:
https://doaj.org/article/8d14ba163b644b7cb91911e12d56920c
Akademický článek
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Autor:
VM Morais, H Massaldi
Publikováno v:
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 15, Iss 1, Pp 2-18 (2009)
Antivenoms have been widely used for more than a century for treating snakebites and other accidents with poisonous animals. Despite their efficacy, the use of heterologous antivenoms involves the possibility of adverse reactions due to activation of
Externí odkaz:
https://doaj.org/article/5eddfdbb763e4e2ba0f38cef24ffa05a
Akademický článek
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Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6588, p 6588 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 12
International Journal of Molecular Sciences
Volume 22
Issue 12
Acute kidney injury (AKI) is a common and severe complication of antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) causing progressive chronic kidney disease (CKD), end-stage renal disease (ESRD) or death. Pathogenic ANCAs, in