Zobrazeno 1 - 10
of 9 848
pro vyhledávání: '"competitive inhibition."'
Publikováno v:
Pharmaceutical Biology, Vol 62, Iss 1, Pp 207-213 (2024)
Context The effect of the active ingredients in traditional Chinese medicines on the activity of cytochrome P450 enzymes (CYP450s) is a critical factor that should be considered in TCM prescriptions. Physcion, the major active ingredient of Rheum spp
Externí odkaz:
https://doaj.org/article/9076d3cfdac24f38b558c0873708e599
Autor:
Selva Sharma, Arumugam a, b, ⁎, Pradeep, Rithwik b, Varghese, Amal Wilson b, Joseph, Roy c, Thekkuveettil, Anoopkumar b, ⁎⁎
Publikováno v:
In Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 15 March 2025 329
Publikováno v:
Pharmaceutical Biology, Vol 60, Iss 1, Pp 1032-1037 (2022)
Context Alpinetin, the major active constitutes of Alpinia katsumata Hayata (Zingiberaceae), has been demonstrated to possess the activity of anti-breast cancer. Cytochrome P450 enzymes (CYP450s) plays vital roles in the biotransformation of various
Externí odkaz:
https://doaj.org/article/e00c131d041a4cb5a370fa4810aaa58a
Autor:
Vinh Quang Mai, Thái Anh Nhan
Publikováno v:
Mathematics, Vol 12, Iss 9, p 1411 (2024)
The H2O2-assisted oxidation by a peroxidase enzyme takes place to help plants maintain the concentrations of organic compounds at physiological levels. Cells regulate the oxidation rate by inhibiting the action of this enzyme. The cells use two inhib
Externí odkaz:
https://doaj.org/article/467b9764140c4b9da8530d2712aeb090
Autor:
Alessandro Pesaresi
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
The formal mechanism of linear mixed and non-competitive enzyme inhibition implies the binding of inhibitors to both the active site of the free enzyme in competition with the substrate, and to an allosteric site on the enzyme-substrate complex. Howe
Externí odkaz:
https://doaj.org/article/2326b8298ced48eda3c7a746c5875d25
Publikováno v:
Biology, Medicine & Natural Product Chemistry, Vol 12, Iss 1, Pp 171-176 (2023)
Diabetes mellitus is a chronic disease that poses a serious global health problem, due to its associated effects on obesity and aging. Therapeutic strategies for targeting diabetes include the downregulation and/or inhibition of enzymes such as a-amy
Externí odkaz:
https://doaj.org/article/e31bd81db7be4176b9680d012dd8d575
Autor:
Gang Li, Juan Feng, Keji Quan, Zhihao Sun, Yuncong Yin, Yinyan Yin, Sujuan Chen, Tao Qin, Daxin Peng, Xiufan Liu
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 530-541 (2022)
A differentiating infected from vaccinated animals (DIVA) vaccine is an ideal strategy for viral eradication in poultry. Here, according to the emerging highly pathogenic H7N9 avian influenza virus (AIV), a DIVA vaccine strain, named rGD4HALo-mH3-TX,
Externí odkaz:
https://doaj.org/article/d63dd32100e34a43a8c244d19504b902
Autor:
Diego Benítez, Jaime Franco, Florencia Sardi, Alejandro Leyva, Rosario Durán, Gahee Choi, Gyongseon Yang, Taehee Kim, Namyoul Kim, Jinyeong Heo, Kideok Kim, Honggun Lee, Inhee Choi, Constantin Radu, David Shum, Joo Hwan No, Marcelo A. Comini
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 912-929 (2022)
Trypanothione synthetase (TryS) catalyses the synthesis of N1,N8-bis(glutathionyl)spermidine (trypanothione), which is the main low molecular mass thiol supporting several redox functions in trypanosomatids. TryS attracts attention as molecular targe
Externí odkaz:
https://doaj.org/article/d6287e9bbb0746028794672207991f63
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Akademický článek
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