Zobrazeno 1 - 10
of 930
pro vyhledávání: '"collagen deposition"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 251-263 (2024)
Peritendinous adhesion (PA) is one of the most common complications following hand surgery and characterized with abnormal hyperplasia of connective tissue and excessive deposition of extracellular matrix. Subsequently, various clinical symptoms such
Externí odkaz:
https://doaj.org/article/ae58d8d41b7a4fb28ac6bf5fb8e9e777
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-11 (2024)
Abstract Postoperative abdominal adhesion is one of the most common complications after abdominal surgery. The Toll-like receptor 4 (TLR4) signaling pathway is one of the most common inflammation-related pathways, and it has been demonstrated that TL
Externí odkaz:
https://doaj.org/article/4c0113f14fd748ca931e2260266fa750
Autor:
Tingyao Hu, Einar Khavaza, Chuxi Liang, Longfei Xing, Xilin Chen, Yue Xu, Weiwei Ma, Farid Mokhtari, Juan Lu, Changqing Guo
Publikováno v:
Journal of Traditional Chinese Medical Sciences, Vol 11, Iss 3, Pp 376-385 (2024)
Objective: To investigate the effects of acupotomy on skeletal muscle fibrosis and collagen deposition in a rabbit knee osteoarthritis (KOA) model. Methods: Rabbits (n = 18) were randomly divided into control, KOA, and KOA + acupotomy (Apo) groups (n
Externí odkaz:
https://doaj.org/article/d18e46f3ac5c4a2ca13d770fe100aace
Autor:
Jie Mei, Yun Cai, Rui Xu, Qing Li, Jiahui Chu, Zhiwen Luo, Yaying Sun, Yuxin Shi, Junying Xu, Di Li, Shuai Liang, Ying Jiang, Jiayu Liu, Zhiwen Qian, Jiaofeng Zhou, Mengyun Wan, Yunlong Yang, Yichao Zhu, Yan Zhang, Yongmei Yin
Publikováno v:
Cancer Communications, Vol 44, Iss 5, Pp 554-575 (2024)
Abstract Background Immune checkpoint blockade (ICB) has revolutionized the treatment of various cancer types. Despite significant preclinical advancements in understanding mechanisms, identifying the molecular basis and predictive biomarkers for cli
Externí odkaz:
https://doaj.org/article/6833b1d444554938b8bc648f6ea01d1d
Autor:
Frederike J. Graelmann, Fabian Gondorf, Yasmin Majlesain, Birte Niemann, Katarina Klepac, Dominic Gosejacob, Marlene Gottschalk, Michelle Mayer, Irina Iriady, Philip Hatzfeld, Sophie K. Lindenberg, Klaus Wunderling, Christoph Thiele, Zeinab Abdullah, Wei He, Karsten Hiller, Kristian Händler, Marc D. Beyer, Thomas Ulas, Alexander Pfeifer, Charlotte Esser, Heike Weighardt, Irmgard Förster, Laia Reverte-Salisa
Publikováno v:
Molecular Metabolism, Vol 85, Iss , Pp 101963- (2024)
Objective: The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor regulating xenobiotic responses as well as physiological metabolism. Dietary AhR ligands activate the AhR signaling axis, whereas AhR activation is negatively r
Externí odkaz:
https://doaj.org/article/0c77233a1c3641c5b95ff046ca0f1936
Autor:
Aline B. Hora, Laiza S. Biano, Ana Carla S. Nascimento, Zaine T. Camargo, Greice I. Heiden, Ricardo L. C. Albulquerque-Júnior, Renata Grespan, Jessica M. D. A. Aragão, Enilton A. Camargo
Publikováno v:
Pharmaceuticals, Vol 17, Iss 10, p 1368 (2024)
Background/Objectives: Wound healing relies on a coordinated process with the participation of different mediators. Natural products are a source of active compounds with healing potential. Isoorientin is a natural flavone recognized as having severa
Externí odkaz:
https://doaj.org/article/aa7bb45bfb7f4f858ca6afe36b343b89
Autor:
Qian Wei, Jianlong Su, Sheng Meng, Yaxi Wang, Kui Ma, Bingmin Li, Ziqiang Chu, Qilin Huang, Wenzhi Hu, Zihao Wang, Lige Tian, Xi Liu, Tanshi Li, Xiaobing Fu, Cuiping Zhang
Publikováno v:
Advanced Science, Vol 11, Iss 13, Pp n/a-n/a (2024)
Abstract Delayed wound healing is a major complication of diabetes, and is associated with impaired cellular functions. Current treatments are unsatisfactory. Based on the previous reports on microRNA expression in small extracellular vesicles (sEVs)
Externí odkaz:
https://doaj.org/article/ecd7ceddb3b646569c32e74fb22c5c71
Autor:
Honglin Xu, Haifeng Miao, Guanghong Chen, Guoyong Zhang, Yue Hua, Yuting Wu, Tong Xu, Xin Han, Changlei Hu, Mingjie Pang, Leyi Tan, Bin Liu, Yingchun Zhou
Publikováno v:
Journal of Ginseng Research, Vol 47, Iss 6, Pp 743-754 (2023)
Background: Myocardial fibrosis post-myocardial infarction (MI) can induce maladaptive cardiac remodeling as well as heart failure. Although 20(S)-ginsenoside Rg3 (Rg3) has been applied to cardiovascular diseases, its efficacy and specific molecular
Externí odkaz:
https://doaj.org/article/2d095b0b7ded4fb4947a4837673c52e4
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 11, Pp 8622-8632 (2023)
Oral submucous fibrosis (OSMF) is a chronic inflammatory disease and a potentially malignant oral disorder, characterized by fibrosis of the oral mucosa. TGF-β signaling pathways have been implicated in the development of OSMF, with areca nut extrac
Externí odkaz:
https://doaj.org/article/f9ee9595b70146c1830e281ca3bcbca1
Autor:
Chenglong Zhang, Yuangui Chen, Lingxuan Yin, Guoxian Deng, Xiaowen Xia, Xiaoshuang Tang, Yifeng Zhang, Junan Yan
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1044 (2024)
Lower urinary tract symptoms (LUTS) are common in postmenopausal women. These symptoms are often linked to decreased estrogen levels following menopause. This study investigated the relationship between estrogen levels, alterations in bladder tissue
Externí odkaz:
https://doaj.org/article/7fd4518a23134eed8b88e7e1ccaeb05d