Zobrazeno 1 - 10
of 2 511
pro vyhledávání: '"collagen I"'
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 27, Iss 7, Pp 832-840 (2024)
Objective(s): Slit guidance ligand 3 (SLIT3) has been identified as a potential therapeutic regulator against fibroblast activity and fibrillary collagen production in an autocrine manner. However, this research aims to investigate the potential role
Externí odkaz:
https://doaj.org/article/532d63f25b054662b67196e1964d033d
Publikováno v:
陆军军医大学学报, Vol 46, Iss 2, Pp 147-154 (2024)
Objective To investigate the effects of silencing connective tissue growth factor (CTGF) gene on growth, apoptosis, and expression of proliferating cell nuclear antigen (PCNA), CTGF, integrin alpha 5 (Itgα5) and collagen Ⅰ (ColⅠ) in rat hepatic
Externí odkaz:
https://doaj.org/article/18912323c71c43fe88ef64bafa334a8c
Autor:
Tumisang Edward Maseko, Eva Peterová, Moustafa Elkalaf, Darja Koutová, Jan Melek, Pavla Staňková, Veronika Špalková, Reem Matar, Halka Lotková, Zuzana Červinková, Otto Kučera
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1179 (2024)
Various strategies have been employed to improve the reliability of 2D, 3D, and co-culture in vitro models of nonalcoholic fatty liver disease, including using extracellular matrix proteins such as collagen I to promote cell adhesion. While studies h
Externí odkaz:
https://doaj.org/article/f49d5b3112a34a999a8e994a2eb89568
Autor:
Giulia Chiabotto, Armina Semnani, Elena Ceccotti, Marco Guenza, Giovanni Camussi, Stefania Bruno
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1849 (2024)
Hepatic fibrosis, arising from prolonged liver injury, entails the activation of hepatic stellate cells (HSCs) into myofibroblast-like cells expressing alpha-smooth muscle actin (α-SMA), thereby driving extracellular matrix deposition and fibrosis p
Externí odkaz:
https://doaj.org/article/77f071d6eb624638965807692843a3b1
Autor:
Serena Artone, Alessia Ciafarone, Francesca Rosaria Augello, Francesca Lombardi, Maria Grazia Cifone, Paola Palumbo, Benedetta Cinque, Giovanni Latella
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8862 (2024)
The mechanism underlying intestinal fibrosis, the main complication of inflammatory bowel disease (IBD), is not yet fully understood, and there is no therapy to prevent or reverse fibrosis. We evaluated, in in vitro cellular models, the ability of di
Externí odkaz:
https://doaj.org/article/a39678790f0e4b44bbefb0e9f8b98615
Autor:
Rasha Zuhair Jasim
Publikováno v:
Iraqi Journal of Pharmaceutical Sciences, Vol 33, Iss 1 (2024)
Meningiomas are the most common primary intracellular slow growing benign tumor that are mostly arisen from meningeothelial (arachnoid) cells which surround the brain and the spinal cord. The aim of the present study is to innovate a biochemical rela
Externí odkaz:
https://doaj.org/article/33e5ea28332b41dab3ed71830b24ed3d
Publikováno v:
Gels, Vol 10, Iss 7, p 450 (2024)
Cell–cell interactions between fibroblasts and immune cells, like macrophages, are influenced by interaction with the surrounding extracellular matrix during wound healing. In vitro hydrogel models that mimic and modulate these interactions, especi
Externí odkaz:
https://doaj.org/article/b7df87ed67de4fb0b3ccae193ac7783a
Autor:
Irena Miler, Mihailo D. Rabasovic, Sonja Askrabic, Andreas Stylianou, Bato Korac, Aleksandra Korac
Publikováno v:
Bioengineering, Vol 11, Iss 4, p 407 (2024)
Changes in the structural properties of the skin due to collagen alterations are an important factor in diabetic skin complications. Using a combination of photonic methods as an optic diagnostic tool, we investigated the structural alteration in rat
Externí odkaz:
https://doaj.org/article/aa17fe0fa010458bb252fa3b0cdbdf00
Autor:
Amira F. Mahdi, Joanne Nolan, Ruth Í. O’Connor, Aoife J. Lowery, Joanna M. Allardyce, Patrick A. Kiely, Kieran McGourty
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionThe extracellular matrix (ECM) has been heavily implicated in the development and progression of cancer. We have previously shown that Annexin A2 is integral in the migration and invasion of breast cancer cells and in the clinical progres
Externí odkaz:
https://doaj.org/article/8df755ab65fa48d3bd61e131535259df