Zobrazeno 1 - 10
of 188
pro vyhledávání: '"cold tumor"'
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 8769-8778 (2024)
Sherin George Shaji,1 Pratikkumar Patel,1 Umar-Farouk Mamani,1 Yuhan Guo,1 Sushil Koirala,1 Chien-Yu Lin,1 Mohammed Alahmari,1 Evanthia Omoscharka,2 Kun Cheng1 1Division of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of M
Externí odkaz:
https://doaj.org/article/a505f01fa9a7410b9658d41112bfdce1
Autor:
Jia Ge, Juan Ge, Gu Tang, Dejun Xiong, Dongyan Zhu, Xiaoling Ding, Xiaorong Zhou, Mengmeng Sang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract Background Pancreatic adenocarcinomas (PAADs) often exhibit a “cold” or immunosuppressive tumor milieu, which is associated with resistance to immune checkpoint blockade therapy; however, the underlying mechanisms are incompletely unders
Externí odkaz:
https://doaj.org/article/7578c8ac36774bd48406d072caad3c01
Autor:
Gholam‐Reza Khosravi, Samaneh Mostafavi, Sanaz Bastan, Narges Ebrahimi, Roya Safari Gharibvand, Nahid Eskandari
Publikováno v:
Cancer Communications, Vol 44, Iss 5, Pp 521-553 (2024)
Abstract Tumors can be classified into distinct immunophenotypes based on the presence and arrangement of cytotoxic immune cells within the tumor microenvironment (TME). Hot tumors, characterized by heightened immune activity and responsiveness to im
Externí odkaz:
https://doaj.org/article/e0f68059fb8f48d7b1206cd6f2c31c3a
Identification and validation of a novel robust glioblastoma prognosis model based on bioinformatics
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37374- (2024)
Background: Glioblastoma (GBM) is a very common primary malignant tumor of the central nervous system (CNS). Aging, macrophage, autophagy, and methylation related genes are hypothesized to be crucial to its pathogenesis. In this study, we aimed to ex
Externí odkaz:
https://doaj.org/article/ad6635d748ec475092f98efb32853625
Autor:
Nicolas Roussot, Marion Thibaudin, Jean-David Fumet, Susy Daumoine, Léa Hampe, Cédric Rébé, Emeric Limagne, Aurélie Lagrange, Victor Herreros, Julie Lecuelle, Hugo Mananet, Alis Ilie, David Rageot, Romain Boidot, Vincent Goussot, Anthony Comte, Pierre Jacob, Françoise Beltjens, Anthony Bergeron, Céline Charon-Barra, Laurent Arnould, Valentin Derangère, Sylvain Ladoire, Caroline Truntzer, François Ghiringhelli
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
A patient with a PD-L1-negative, TMB-low, KEAP1/STK11 co-mutated metastatic non-small cell lung cancer (NSCLC) experienced a multisite radiological progression at 3 months after initiation of chemoimmunotherapy as first-line treatment for metastatic
Externí odkaz:
https://doaj.org/article/720f9ebdb12b41d5a9b653e489118e2d
Identification and validation of a novel robust glioblastoma prognosis model based on bioinformatics
Autor:
Zhang, Le a, c, 1, Yan, Xiaoling d, 1, Wang, Yahong e, 1, Wang, Qin a, c, ⁎⁎⁎, Yan, Hua a, f, ⁎⁎, Yan, Yan a, b, c, ⁎
Publikováno v:
In Heliyon 30 September 2024 10(18)
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/43da582f92c44426970f44f2920f8401
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e29171- (2024)
Objective: MRPS24 (Mitochondrial Ribosomal Protein S24) belongs to the mitochondrial ribosomal protein family, which participates in the protein synthesis of the mitochondrion. However, the relationship of MRPS24 with lung adenocarcinoma (LUAD) remai
Externí odkaz:
https://doaj.org/article/07e53d485cc741b8812288874af00fc7
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionNeuroblastoma (NB) is a common extracranial tumor in children and is highly heterogeneous. The factors influencing the prognosis of NB are not simple.MethodsTo investigate the effect of cell senescence on the prognosis of NB and tumor imm
Externí odkaz:
https://doaj.org/article/e9604c62449143e48a359be21a8c3242
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionImmune checkpoint blockade (ICB) has revolutionized the therapy landscape of malignancy melanoma. However, the clinical benefits from this regimen remain limited, especially in tumors lacking infiltrated T cells (known as “cold” tumor
Externí odkaz:
https://doaj.org/article/ecf7008ee2df4b6da46acfa6fd9b25de