Estradiol protects hair cells from cisplatin-induced ototoxicity via Nrf2 activation

Autor: Masahiro Adachi, Kota Yanagizono, Yasuhito Okano, Hitoshi Koizumi, Isao Uemaetomari, Keiji Tabuchi

Publikováno v: Redox Report, Vol 28, Iss 1 (2023)

ABSTRACTCisplatin-induced ototoxicity is caused by reactive oxygen species. It has been recognized that estradiol (E2) regulates redox balance. However, little is known about the protective mechanisms of E2 against cisplatin-induced ototoxicity. In t

Externí odkaz: https://doaj.org/article/4740cff77f354bd398f1334805e3e443

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A laser interferometer for sub-nanometre measurements in the cochlea

Autor: Fabio Mammano, Jonathan Ashmore

Publikováno v: Journal of neuroscience methods. 60(1-2)

A modification of a light microscope is described here which allows measurement of nanometre movements along the optical axis of the microscope. The light path is reflected off 10-microns-diametre small glass beads which are individually imaged with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea9c85de800357e2c229dcd0b3a9493
https://pubmed.ncbi.nlm.nih.gov/8544491

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A model of ionic transport and osmotic volume control in cochlear outer hair cells.

Autor: West T; UCL Ear Institute , 332 Gray's Inn Road, London WC1X 8EE , UK., Ashmore J; UCL Ear Institute , 332 Gray's Inn Road, London WC1X 8EE , UK ; Department of Neuroscience, Physiology and Pharmacology , UCL , Gower St., London WC1E 6BT , UK.

Publikováno v: Interface focus [Interface Focus] 2014 Dec 06; Vol. 4 (6), pp. 20140018.