Zobrazeno 1 - 10
of 25
pro vyhledávání: '"clonal mutations"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 7852 (2023)
More than 80,000 new cases of bladder cancer are estimated to be diagnosed in 2023. However, the 5-year survival rate for bladder cancer has not changed in decades, highlighting the need for prevention. Numerous cancer-causing mutations are present i
Externí odkaz:
https://doaj.org/article/ef9f28b23d654f2eadc3eaefbe5de648
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Modern cancer treatment strategies aim to target tumour specific genetic (or epigenetic) alterations. Treatment response improves if these alterations are clonal, i.e. present in all cancer cells within tumours. However, the ident
Externí odkaz:
https://doaj.org/article/f583a33bade54775bdaee56c92172c00
Autor:
Sydney R. Grant, Spencer R. Rosario, Andrew D. Patentreger, Nico Shary, Megan E. Fitzgerald, Prashant K. Singh, Barbara A. Foster, Wendy J. Huss, Lei Wei, Gyorgy Paragh
Publikováno v:
Cancers; Volume 15; Issue 5; Pages: 1612
Mutations found in skin are acquired in specific patterns, clustering around mutation-prone genomic locations. The most mutation-prone genomic areas, mutation hotspots, first induce the growth of small cell clones in healthy skin. Mutations accumulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb25ed97304e38f6c049b850361ac17
https://doi.org/10.21203/rs.3.rs-2216887/v1
https://doi.org/10.21203/rs.3.rs-2216887/v1
Autor:
S. Scalera, B. Ricciuti, M. Mazzotta, N. Calonaci, J.V. Alessi, L. Cipriani, G. Bon, B. Messina, G. Lamberti, A. Di Federico, F. Pecci, S. Milite, E. Krasniqi, M. Barba, P. Vici, A. Vecchione, F. De Nicola, L. Ciuffreda, F. Goeman, M. Fanciulli, S. Buglioni, E. Pescarmona, B. Sharma, K.D. Felt, J. Lindsay, S.J. Rodig, R. De Maria, G. Caravagna, F. Cappuzzo, G. Ciliberto, M.M. Awad, M. Maugeri-Saccà
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology.
KEAP1 mutations have been associated with reduced survival in lung adenocarcinoma (LUAD) patients treated with immune checkpoint inhibitors (ICIs), particularly in the presence of STK11/KRAS alterations. We hypothesized that, beyond co-occurring geno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0afc38891a61c174e2134a35a9bd0edf
https://pubmed.ncbi.nlm.nih.gov/36526124
https://pubmed.ncbi.nlm.nih.gov/36526124
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Antić, Željko
Acute lymphoblastic leukemia (ALL) is the most common malignancy in children. Improvements in the treatment made over the last decades have resulted in increased overall survival, now reaching 90%. However, around 10% of children experience disease r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::186d974c8c636982de6392a933c4128e
https://dspace.library.uu.nl/handle/1874/416632
https://dspace.library.uu.nl/handle/1874/416632
Acute lymphoblastic leukemia (ALL) is the most common malignancy in children. Improvements in the treatment made over the last decades have resulted in increased overall survival, now reaching 90%. However, around 10% of children experience disease r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___00893::28ace4dbaaf489da2c1b97da25381d38
https://doi.org/10.33540/1140
https://doi.org/10.33540/1140
Autor:
Opasic, Luka
Despite tremendous resource investment in the fight against cancer over the last 50 years, prognosis of the late-stage malignant disease is almost inevitably unfavourable as most cancers are resilient against treatment. The source of this cancer resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______660::caaa31cd43b0aef81412e3f30ed7827a
https://macau.uni-kiel.de/receive/macau_mods_00000496
https://macau.uni-kiel.de/receive/macau_mods_00000496