Zobrazeno 1 - 10
of 410
pro vyhledávání: '"clonal heterogeneity"'
Autor:
Fernando Aldana-Salazar, Nelson Rangel, María José Rodríguez, César Baracaldo, María Martínez-Agüero, Milena Rondón-Lagos
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4167 (2024)
In the department of Boyacá, Colombia, agriculture stands as one of the primary economic activities. However, the escalating utilization of pesticides within this sector has sparked concern regarding its potential correlation with elevated risks of
Externí odkaz:
https://doaj.org/article/e08bc739f68e4203b0f21605652ae265
Autor:
Valentina Camargo-Herrera, Giovanny Castellanos, Nelson Rangel, Guillermo Antonio Jiménez-Tobón, María Martínez-Agüero, Milena Rondón-Lagos
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4478 (2024)
Chromosomal instability (CIN), defined by variations in the number or structure of chromosomes from cell to cell, is recognized as a distinctive characteristic of cancer associated with the ability of tumors to adapt to challenging environments. CIN
Externí odkaz:
https://doaj.org/article/cb6115f7b0e944769db9ed2e6e4cce2a
Publikováno v:
Breast Cancer: Targets and Therapy, Vol Volume 15, Pp 189-211 (2023)
Giovanny Castellanos,1,2 Duván Sebastián Valbuena,2 Erika Pérez,2 Victoria E Villegas,3 Milena Rondón-Lagos2 1Maestría en Ciencias Biológicas, Universidad Pedagógica y Tecnológica de Colombia, Tunja, Colombia; 2School of Biological Sciences,
Externí odkaz:
https://doaj.org/article/625052928b934db5bf3f3898b97e9ef0
Autor:
Shirin Bonni, David N. Brindley, M. Dean Chamberlain, Nima Daneshvar-Baghbadorani, Andrew Freywald, Denise G. Hemmings, Sabine Hombach-Klonisch, Thomas Klonisch, Afshin Raouf, Carrie Simone Shemanko, Diana Topolnitska, Kaitlyn Visser, Franco J. Vizeacoumar, Edwin Wang, Spencer B. Gibson
Publikováno v:
Cancers, Vol 16, Iss 5, p 911 (2024)
Metastasis remains a major challenge in treating breast cancer. Breast tumors metastasize to organ-specific locations such as the brain, lungs, and bone, but why some organs are favored over others remains unclear. Breast tumors also show heterogenei
Externí odkaz:
https://doaj.org/article/2460a0b5effa4f99aea3b056ece2835c
Publikováno v:
Hematology, Vol 27, Iss 1, Pp 684-690 (2022)
Background Epstein Barr virus positive (EBV+) immunodeficiency-associated lymphoproliferative disorders (IA-LPD) are heterogeneous diseases with variable treatment strategies that are not well-defined.Case presentation A 68-year-old woman with system
Externí odkaz:
https://doaj.org/article/cf7cac74a1654390ae310c0ba9883ad8
Autor:
Mireia Ramos‐Muntada, Juan L. Trincado, Joan Blanco, Clara Bueno, Virginia C. Rodríguez‐Cortez, Alex Bataller, Belén López‐Millán, Claire Schwab, Margarita Ortega, Pablo Velasco, Maria L. Blanco, Josep Nomdedeu, Manuel Ramírez‐Orellana, Alfredo Minguela, Jose L. Fuster, Esther Cuatrecasas, Mireia Camós, Paola Ballerini, Gabriele Escherich, Judith Boer, Monique DenBoer, Jesús M. Hernández‐Rivas, Maria J. Calasanz, Giovanni Cazzaniga, Christine J. Harrison, Pablo Menéndez, Oscar Molina
Publikováno v:
Molecular Oncology, Vol 16, Iss 16, Pp 2899-2919 (2022)
B‐cell acute lymphoblastic leukemia (B‐ALL) is the commonest childhood cancer. High hyperdiploidy (HHD) identifies the most frequent cytogenetic subgroup in childhood B‐ALL. Although hyperdiploidy represents an important prognostic factor in ch
Externí odkaz:
https://doaj.org/article/c4efc3858e8a4dd59893e2d44eb72c0d
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Acute myeloid leukemia (AML) is a polyclonal and heterogeneous hematological malignancy. Relapse and refractory after induction chemotherapy are still challenges for curing AML. Leukemia stem cells (LSCs), accepted to originate from hematopoietic ste
Externí odkaz:
https://doaj.org/article/4e223846df3f47a1b522f526bd7d0c43
Akademický článek
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Akademický článek
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Autor:
Jonas Weiße, Julia Rosemann, Lisa Müller, Matthias Kappler, Alexander W. Eckert, Markus Glaß, Danny Misiak, Stefan Hüttelmaier, Wolfgang G. Ballhausen, Mechthild Hatzfeld, Monika Haemmerle, Tony Gutschner
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-23 (2021)
Abstract Background Cancer metastases are the main cause of lethality. The five-year survival rate for patients diagnosed with advanced stage oral cancer is 30%. Hence, the identification of novel therapeutic targets is an urgent need. However, tumor
Externí odkaz:
https://doaj.org/article/2fab5abc84ca4a3daabdfded742fbe0b