Zobrazeno 1 - 10
of 2 377
pro vyhledávání: '"clodronate"'
Publikováno v:
Particle and Fibre Toxicology, Vol 21, Iss 1, Pp 1-11 (2024)
Abstract Background Alveolar macrophages (AMs) have been predicted to affect the pulmonary clearance of nanomaterials; however, their qualitative and quantitative roles are poorly understood. In this study, carbon black nanoparticles (CBNPs) were ins
Externí odkaz:
https://doaj.org/article/42fc734f9f8b4cdba1f68d9fdddff985
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Excessive macrophage activation and production of pro-inflammatory cytokines are hallmarks of the Cytokine Storm Syndrome (CSS), a lethal condition triggered by sepsis, autoimmune disorders, and cancer immunotherapies. While depletion of macrophages
Externí odkaz:
https://doaj.org/article/0a541ea526c4412cbc955ded6b5469db
Autor:
Guanglin Song, Fanghao Cai, Liangzhong Liu, Zaicheng Xu, Yuan Peng, Zhenzhou Yang, Xiaoyue Zhang
Publikováno v:
Translational Oncology, Vol 47, Iss , Pp 102029- (2024)
Radiation-induced lung injury (RILI) is a severe complication arising from thoracic tumor radiotherapy, which constrains the possibility of increasing radiation dosage. Current RILI therapies provide only limited relief and may result in undesirable
Externí odkaz:
https://doaj.org/article/afe47ccd634d486f8e36c7d2a1d4af42
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-25 (2024)
Abstract Background Since the 1990s, evidence has accumulated that macrophages promote peripheral nerve regeneration and are required for enhancing regeneration in the conditioning lesion (CL) response. After a sciatic nerve injury, macrophages accum
Externí odkaz:
https://doaj.org/article/0091155cbdae4545a8bcb622782029dd
Publikováno v:
Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-5 (2024)
Abstract Background Complex regional pain syndrome type I is a pathological condition characterized by an exaggerated response of tissues to low or moderate pain stimuli. The exact pathogenesis and optimal medical treatment for complex regional pain
Externí odkaz:
https://doaj.org/article/0db4564cbc7449faac0d07f32d962b43
Autor:
Erwin K. Gudenschwager Basso, Jing Ju, Eman Soliman, Caroline de Jager, Xiaoran Wei, Kevin J. Pridham, Michelle L. Olsen, Michelle H. Theus
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Monocytes represent key cellular elements that contribute to the neurological sequela following brain injury. The current study reveals that trauma induces the augmented release of a transcriptionally distinct CD115+/Ly6Chi monocyte populati
Externí odkaz:
https://doaj.org/article/4a71437ef1c1430cb5de1c3e6795ff40
Autor:
Tae Hyeon Choi, Ran Ji Yoo, Ji Yong Park, Ji Yoon Kim, Young Chan Ann, Jeongbin Park, Jin Sil Kim, Kyuwan Kim, Yu Jin Shin, Yong Jin Lee, Kyo Chul Lee, Jisu Park, Hyewon Chung, Seung Hyeok Seok, Hyung-Jun Im, Yun-Sang Lee
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Immunotherapy with clodronate-encapsulated liposomes, which induce macrophage depletion, has been studied extensively. However, previously reported liposomal formulation-based drugs (Clodrosome® and m-Clodrosome®) are limited by
Externí odkaz:
https://doaj.org/article/73dd56cc7faf45859548ae9a93d8c652
Publikováno v:
Journal of Innate Immunity, Vol 16, Iss 1, Pp 66-79 (2023)
Introduction: Hematophagous arthropods can acquire and transmit several pathogens of medical importance. In ticks, the innate immune system is crucial in the outcome between vector-pathogen interaction and overall vector competence. However, the spec
Externí odkaz:
https://doaj.org/article/2397506cee074c058bec0c03d39ec43c
Autor:
Shuang Ding, Yuhan Wang, Zhiting Liu, Yuwei Du, Yi Zhou, Yahui Liu, Jingfang Sun, Yue Li, Lingyu Zeng
Publikováno v:
Regenerative Therapy, Vol 24, Iss , Pp 54-63 (2023)
Introduction: Clodronate-Liposomes (Clod-Lipo) injection after hematopoietic stem cell transplantation (HSCT) has been shown to be detrimental to hematopoietic reconstitution after transplantation, and our previous study showed that Clod-Lipo injecti
Externí odkaz:
https://doaj.org/article/54e9f9e637c44f999b9e9d9b232052e6
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8435 (2024)
Clodronate (Clod), a first-generation bisphosphonate, acts as a natural analgesic inhibiting vesicular storage of the nociception mediator ATP by vesicular nucleotide transporter (VNUT). Epidermal keratinocytes participate in cutaneous nociception, a
Externí odkaz:
https://doaj.org/article/2c3af27674b941e083d305fc8c1cab2f