Adaptive designs in clinical trials: a systematic review-part I.

Autor: Ben-Eltriki M; Department of Pharmacology and Therapeutics, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada. mbeneltriki@alumni.ubc.ca.; George and for Fay Yee Centre Healthcare Innovation, Winnipeg, MB, Canada. mbeneltriki@alumni.ubc.ca.; Cochrane Hypertension Review Group, Therapeutic Initiative, University of British Columbia, Vancouver, BC, Canada. mbeneltriki@alumni.ubc.ca., Rafiq A; Department of Pharmacology and Therapeutics, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada., Paul A; Department of Pharmacology and Therapeutics, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada., Prabhu D; George and for Fay Yee Centre Healthcare Innovation, Winnipeg, MB, Canada., Afolabi MOS; Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada., Baslhaw R; George and for Fay Yee Centre Healthcare Innovation, Winnipeg, MB, Canada.; Department of Community Health Sciences, University of Manitoba, Winnipeg, MB, Canada., Neilson CJ; Neil John Maclean Health Sciences Library, University of Manitoba, Winnipeg, MB, Canada., Driedger M; Department of Community Health Sciences, University of Manitoba, Winnipeg, MB, Canada., Mahmud SM; Department of Community Health Sciences, University of Manitoba, Winnipeg, MB, Canada., Lacaze-Masmonteil T; Department of Pediatrics, Cumming School of Medicine, University of Calgary, Alberta, Canada., Marlin S; Clinical Trials Ontario, Toronto, Ontario, Canada., Offringa M; Department of Paediatrics, Management & Evaluation, Institute of Health Policy, University of Toronto, Ontario, Canada.; The Hospital for Sick Children, Toronto, Ontario, Canada., Butcher N; The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada., Heath A; The Hospital for Sick Children, Toronto, Ontario, Canada.; Division of Biostatistics, Dalla Lana School of Public Health, Child Health Evaluative Sciences, University of Toronto, ScientistToronto, Ontario, Canada.; Department of Statistical Science, University College London, London, UK., Kelly LE; Department of Pharmacology and Therapeutics, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada. lauren.kelly@umanitoba.ca.; George and for Fay Yee Centre Healthcare Innovation, Winnipeg, MB, Canada. lauren.kelly@umanitoba.ca.; Children's Hospital Research Institute of Manitoba, Winnipeg, MB, Canada. lauren.kelly@umanitoba.ca.; Departments of Pharmacology and Therapeutics, Community Health Sciences, University of Manitoba, 417-753 McDermot Ave, Winnipeg, Manitoba, R3E0T6, Canada. lauren.kelly@umanitoba.ca.

Publikováno v: BMC medical research methodology [BMC Med Res Methodol] 2024 Oct 04; Vol. 24 (1), pp. 229. Date of Electronic Publication: 2024 Oct 04.

Similarities and Differences Between Pragmatic Trials and Hybrid Effectiveness-Implementation Trials.

Autor: Fortney JC; Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle, WA, USA. fortneyj@uw.edu.; Department of Veterans Affairs, Health Systems Research, Center of Innovation for Veteran-Centered and Value-Driven Care, Seattle, WA, USA. fortneyj@uw.edu., Curran GM; College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Department of Nursing and Midwifery, University of Limerick, Limerick, Ireland., Lyon AR; Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle, WA, USA., Check DK; Department of Population Health Sciences, School of Medicine, Duke University, Durham, NC, USA., Flum DR; Department of Surgery, School of Medicine, University of Washington, Seattle, WA, USA.

Publikováno v: Journal of general internal medicine [J Gen Intern Med] 2024 Jul; Vol. 39 (9), pp. 1735-1743. Date of Electronic Publication: 2024 Apr 16.

Improving Access to Patient-Focused, Decentralized Clinical Trials Requires Streamlined Regulatory Requirements: An ASCO Research Statement.

Autor: Thota R; Intermountain Health, Murray, UT., Hurley PA; American Society of Clinical Oncology, Alexandria VA., Miller TM; Icahn School of Medicine at Mount Sinai, Tisch Cancer Institute, New York, NY., Bruinooge SS; American Society of Clinical Oncology, Alexandria VA., Lipset C; Decentralized Trials and Research Alliance, San Diego, CA., Harvey RD; Winship Cancer Institute of Emory University, Atlanta, GA., Black LJ; Sanford Health, Sioux Falls, SD., Dinsdale A; Montana Cancer Consortium, Billings, MT., Merrill JK; American Society of Clinical Oncology, Alexandria VA., Pollastro T; Metastatic Breast Cancer Alliance, New York, NY., Prindiville SA; NCI Coordinating Center for Clinical Trials, Bethesda, MD., Rizvi MA; Heimann Cancer Center, Asante Health System, Medford, OR., Sherwood S; American Society of Clinical Oncology, Alexandria VA., Nowakowski GS; Mayo Clinic, Rochester, MN.

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2024 Nov 20; Vol. 42 (33), pp. 3986-3995. Date of Electronic Publication: 2024 Jul 30.

Clinical trials for Lennox-Gastaut syndrome: Challenges and priorities.

Autor: Knowles JK; Department of Neurology, Stanford University School of Medicine, Stanford, California, USA., Warren AEL; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Mohamed IS; Department of Pediatrics, University of Alabama, Birmingham, Alabama, USA., Stafstrom CE; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Koh HY; Department of Pediatrics, Section of Neurology and Developmental Neuroscience, Baylor College of Medicine, Houston, Texas, USA., Samanta D; Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA., Shellhaas RA; Department of Neurology, Washington University in St. Louis, St. Louis, Missouri, USA., Gupta G; Department of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA., Dixon-Salazar T; Lennox-Gastaut Syndrome Foundation, San Diego, California, USA., Tran L; Jane and John Justin Institute for Mind Health, Cook Children's Medical Center, Fort Worth, Texas, USA., Bhatia S; Division of Pediatric Neurology, Medical University of South Carolina, Charleston, South Carolina, USA., McCabe JM; Pediatric Epilepsy Research Consortium, Niwot, Colorado, USA., Patel AD; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio, USA.; The Center for Clinical Excellence, Nationwide Children's Hospital, Columbus, Ohio, USA., Grinspan ZM; Department of Pediatrics, Weill Cornell Medicine, New York, New York, USA.

Publikováno v: Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2024 Nov; Vol. 11 (11), pp. 2818-2835. Date of Electronic Publication: 2024 Oct 23.

Group sequential designs for clinical trials when the maximum sample size is uncertain.

Autor: Yarahmadi A; Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK., Dodd LE; Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases, Rockville, Maryland, USA., Jaki T; Faculty of Informatics and Data Science, University of Regensburg, Regensburg, Germany.; MRC Biostatistics Unit, University of Cambridge, Cambridge, UK., Horby P; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Stallard N; Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK.

Publikováno v: Statistics in medicine [Stat Med] 2024 Oct 30; Vol. 43 (24), pp. 4667-4683. Date of Electronic Publication: 2024 Aug 21.