Novel topical allogeneic bone-marrow-derived mesenchymal stem cell treatment of hard-to-heal diabetic foot ulcers: a proof of concept study

Autor: Jonas Askø Andersen, Anne Rasmussen, Marie Frimodt-Møller, Susanne Engberg, Esther Steeneveld, Klaus Kirketerp-Møller, Timothy O’Brien, Peter Rossing

Publikováno v: Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-9 (2022)

Abstract Aim The aim of this study was to investigate safety of treating diabetic foot ulcers with a topically administered mesenchymal stem cell product. Method Individuals with diabetes, peripheral neuropathy, toe blood pressure > 39 mmHg and non-i

Externí odkaz: https://doaj.org/article/5cef4fa41ad54c7f90a0e81115c0bcab

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Phase I clinical trial of cell therapy in patients with advanced chronic obstructive pulmonary disease: follow-up of up to 3 years

Autor: Talita Stessuk, Milton Artur Ruiz, Oswaldo Tadeu Greco, Aldemir Bilaqui, Maria Jose de Oliveira Ribeiro-Paes, Joao Tadeu Ribeiro-Paes

Publikováno v: Revista Brasileira de Hematologia e Hemoterapia, Vol 35, Iss 5, Pp 352-357 (2013)

BACKGROUND Chronic obstructive pulmonary disease is a major inflammatory disease of the airways and an enormous therapeutic challenge. Within the spectrum of chronic obstructive pulmonary disease, pulmonary emphysema is characterized by the destructi

Externí odkaz: https://doaj.org/article/bbc928ba10144e339ab0eeff2b440741

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Phase I/II Study of Stem-Cell Transplantation Using a Single Cord Blood Unit Expanded Ex Vivo With Nicotinamide

Autor: Jaap Jan Boelens, Rabi Hanna, Francesco Frassoni, Pau Montesinos, Daniela Cilloni, Stephen Wease, Patrick J. Stiff, William Hwang, Guillermo Sanz, Joanne Kurtzberg, Laurence S. Freedman, Jürgen Kuball, John E. Wagner, Mitchell E. Horwitz, Navneet S. Majhail, David Valcárcel, Stefan Nierkens, Beth Blackwell, Liang Piu Koh, Madan Jagasia

Publikováno v: Journal of Clinical Oncology
Journal of Clinical Oncology, 37(5), 367. American Society of Clinical Oncology
JOURNAL OF CLINICAL ONCOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
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Purpose Increasing the number of hematopoietic stem and progenitor cells within an umbilical cord blood (UCB) graft shortens the time to hematopoietic recovery after UCB transplantation. In this study, we assessed the safety and efficacy of a UCB gra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6064c478947d8860f9da8dc9549c2682
http://europepmc.org/articles/PMC6368416