Easy analysis of bacterial whole-genome sequencing data for clinical microbiologists using open-source Galaxy platform: Characterization of ESBL-producing Enterobacterales from bloodstream infections

Autor: Aimé Berwa, Yvan Caspar

Publikováno v: Journal of Global Antimicrobial Resistance, Vol 39, Iss , Pp 153-158 (2024)

Objectives: Clinical microbiologists require easy-to-use open access tools with graphical interfaces to perform bacterial whole-genome sequencing (WGS) in routine practice. This study aimed to build a bioinformatics pipeline on the open-source Galaxy

Externí odkaz: https://doaj.org/article/f1a12fd77a724837bb1a15e07d9a2cd0

Enhancing ascitic fungal infection diagnosis through next-generation sequencing: a pilot study in surgical ICU patients

Autor: Sara Posadas-Cantera, Negin Mehrbarzin, Simon Wetzel, Hanna Goelz, Lampros Kousoulas, Stefan Utzolino, Georg Häcker, Mohamed Tarek Badr

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)

ObjectivesAscites, often associated with critical pathologies such as liver cirrhosis or bowel perforation, can be complicated by fungal infection, increasing mortality especially in intensive care settings and demanding rapid diagnosis and adequate

Externí odkaz: https://doaj.org/article/c4dd8be304c54defae56a319640dd0a0

A summary of the main themes and findings presented at the ASM Intermountain Branch meeting (2024)

Autor: Jay Radke, Javier Ochoa-Repåraz, Jamee Nixon, Sajal Acharya, Haley Bridgewater, Joshua Burger, Abigail Cheever, Robert Darby, William Doyle, Alka Gaur, Eva Githuku, Rose Goodman, Topher Haynie, Hannah Hedelius, Kristina Hill, Misha Iqbal, Salma Laabi, Carlos Moreno, Melinda Moss, Nagama Parveen, Naomi Rapier-Sharman, Sara Sadeghi, Saeed Saleh, Sean Schumacher, Miranda Sharp, Noah Souza, Soni Thapa, Shule Aggabao, David Amsbury, Sheena Isabelle Bautista, Atalie Bogh, Aaron Bohn, Cade Brink, B. Shaun Bryner, James Cannon, Scot Carrington, Hayzen Chamberlain, Alex Cherry, McKaylin Cole, Edgar Corrales, Caz Cullimore, Sophie Daines, Payson Danielson, Monterey Domike, Matthew East, Bronwyn Ellis, Taryn Evans, Zach Fears, Paige Fellars, Tate Fisher, Braxton Floyd, Trenton Gibson, Mason Gueller, Heather Gupta, Jacob Gwilliam, Mackenzie Hansen, Jacob Hardy, Christopher Harrell, Rebecca Hassell, Wesley Hendricks, Colby Hendrix, Hirsche Henstrom, Kelly Hernandez Sanguino, George Higgins, Hyunbi Hwang, Matt Jackson, Conner Jensen, Austin Johnson, Chloe Kang, Sehi Kim, Alexandra LaFollette, Phoenix Larsen, Abbey Larson, Bryson Leary, Jayden Longhurst, Michael Mann, Isreal Martinez, Brooklyn Matthews, Cody McStraw, Ninahazwe Mireill, Rachel Moffat, Peter Mourik, Madelyn Mudrow, Mailon Odell, Blake Oler, Natalie Olsen, Nazanin Paymard, Spencer T. Payne, Levi Pearson, Josh Peter, Tiffani Peterson, Daniel Puentes Navarro, Kyla Radke, Joseph Richardson, Russell Ridd, Akir Rowe, Rylan Schmanski, Jacob Scott, Samuel Scott, Mya Simpkins, Madalyne Sisk, Tyler Smith, Brinley Smith, Jacob Sy, Gisselle Trejo, Bartel Van Oostendorp, Ethan Walbom, Rebecca Whetten, Dallin Zollinger, Miriam Braunstein, Donald P. Breakwell, Anirban Chakraborty, Matthew Crook, Michele Culumber, Wayne Hatch, Victor M. Jimenez, Jr., Wales P. Nematollahi, Michael Olson, Mark Poritz, Seth Ririe, Jeffrey Schachterle, Lisa Wiltbank, Todd Kelson, Brett E. Pickett

Publikováno v: mSphere, Vol 9, Iss 7 (2024)

ABSTRACT The annual meeting for the Intermountain Branch was held in April 2024 on the campus of Brigham Young University. There were 127 branch members from Utah, Idaho, and Nevada who attended the meeting and were composed of undergraduate students

Externí odkaz: https://doaj.org/article/37d271f25abc49d3ae9d6985f02e4fc2

Deep learning model to discriminate diverse infection types based on pairwise analysis of host gene expression

Autor: Jize Xie, Xubin Zheng, Jianlong Yan, Qizhi Li, Nana Jin, Shuojia Wang, Pengfei Zhao, Shuai Li, Wanfu Ding, Lixin Cheng, Qingshan Geng

Publikováno v: iScience, Vol 27, Iss 6, Pp 109908- (2024)

Summary: Accurate detection of pathogens, particularly distinguishing between Gram-positive and Gram-negative bacteria, could improve disease treatment. Host gene expression can capture the immune system’s response to infections caused by various p

Externí odkaz: https://doaj.org/article/6ff7ccf657524ea2b9a69a9c0693b95d