Zobrazeno 1 - 10
of 1 746
pro vyhledávání: '"circulating cell‐free DNA"'
Autor:
María Gallardo‐Gómez, Lara Costas‐Ríos, Carlos A. Garcia‐Prieto, Lara Álvarez‐Rodríguez, Luis Bujanda, Maialen Barrero, Antoni Castells, Francesc Balaguer, Rodrigo Jover, Manel Esteller, Antoni Tardío Baiges, Joaquín González‐Carreró Fojón, Joaquín Cubiella, Loretta De Chiara
Publikováno v:
Molecular Oncology, Vol 18, Iss 11, Pp 2696-2713 (2024)
The clinical relevance of the colorectal cancer serrated pathway is evident, but the screening of serrated lesions remains challenging. We aimed to characterize the serum methylome of the serrated pathway and to evaluate circulating cell‐free DNA (
Externí odkaz:
https://doaj.org/article/52a5b5b7bba14705bc89a233d4909de9
Publikováno v:
Tzu-Chi Medical Journal, Vol 36, Iss 1, Pp 67-75 (2024)
Objectives: Determining a diagnosis for non-Tuberculous mycobacterium (NTM)-lung disease (LD) remains difficult. The value of circulating cell-free DNA (cfDNA) secreted from microbes has been established in the detection of pathogens in septic patien
Externí odkaz:
https://doaj.org/article/c265e7b6b38a41d5b1af520f43472bee
Autor:
Elena Giordani, Matteo Allegretti, Alberto Sinibaldi, Francesco Michelotti, Gianluigi Ferretti, Elena Ricciardi, Giovanna Ziccheddu, Fabio Valenti, Simona Di Martino, Cristiana Ercolani, Diana Giannarelli, Grazia Arpino, Stefania Gori, Claudia Omarini, Alberto Zambelli, Emilio Bria, Ida Paris, Simonetta Buglioni, Patrizio Giacomini, Alessandra Fabi
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-11 (2024)
Abstract Background During targeted treatment, HER2-positive breast cancers invariably lose HER2 DNA amplification. In contrast, and interestingly, HER2 proteins may be either lost or gained. To longitudinally and systematically appreciate complex/di
Externí odkaz:
https://doaj.org/article/92bb4cafdd7145c5a75ef4fcaf8a3e78
Autor:
Nada Ezzeldin, Dalia El-Lebedy, Mirhane Hassan, Alaa Omar Shalaby, Sabah Ahmed Mohamed Hussein, Ahmed Mohamed Gharib, Gehan Hamdy, Asmaa Mahmoud Mohammed, Abeer Ramadan, Mohamed Emam Sobeih
Publikováno v:
Journal of the Egyptian National Cancer Institute, Vol 36, Iss 1, Pp 1-9 (2024)
Abstract Background Analysis of free DNA molecules shed from tumour cells in plasma of patients referred as circulating tumour DNA (ctDNA) with reference to physiological circulating cell-free DNA (cfDNA) is nowadays exploited as liquid biopsy and is
Externí odkaz:
https://doaj.org/article/e91bae18ae024eb4a954fa00c3e0aa97
Autor:
I. Vanni, L. Pastorino, V. Andreotti, D. Comandini, G. Fornarini, M. Grassi, A. Puccini, E. T. Tanda, A. Pastorino, V. Martelli, L. Mastracci, F. Grillo, F. Cabiddu, A. Guadagno, S. Coco, E. Allavena, F. Barbero, W. Bruno, B. Dalmasso, S. E. Bellomo, C. Marchiò, F. Spagnolo, S. Sciallero, E. Berrino, P. Ghiorzo
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Comprehensive next-generation sequencing is widely used for precision oncology and precision prevention approaches. We aimed to determine the yield of actionable gene variants, the capacity to uncover hereditary predisposition and
Externí odkaz:
https://doaj.org/article/9b575f65c497470eb8c342650e30b55f
Autor:
Mona Wang, Xiaohan Fan, Boyang Huang, Kaifeng Pan, Markus Gerhard, Raquel Mejías‐Luque, Yang Zhang
Publikováno v:
Clinical and Translational Discovery, Vol 4, Iss 4, Pp n/a-n/a (2024)
Abstract Objective Screening and early diagnosis of gastric cancer (GC) are crucial for improved prognosis. However, gastroscopic screening is not feasible in large populations due to its high cost and invasive nature. The detection of circulating ce
Externí odkaz:
https://doaj.org/article/1d509c8ca41849c99ce2b326dee93e3d
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/a719c2a9d04740c59cfd6bf8b93bed21
Autor:
Kazuya Yasui, Toshiaki Toshima, Ryo Inada, Yuzo Umeda, Shuya Yano, Hiroaki Tanioka, Akihiro Nyuya, Toshiyoshi Fujiwara, Takeshi Yamada, Yoshio Naomoto, Ajay Goel, Takeshi Nagasaka
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-8 (2024)
Abstract This study investigates methylation patterns in circulating cell-free DNA (ccfDNA) for their potential role in colorectal cancer (CRC) detection and the monitoring of treatment response. Through methylation microarrays and quantitative PCR a
Externí odkaz:
https://doaj.org/article/1c14b70e34c74e49905948114b61e039
Publikováno v:
Gastroenterology Insights, Vol 15, Iss 1, Pp 107-121 (2024)
This study aims to investigate the long-term prognostic utility of circulating tumour DNA (ctDNA) KRAS mutations in colorectal cancer (CRC) patients and compare this with KRAS mutations in matched tissue samples. Tumour tissue (n = 107) and ctDNA (n
Externí odkaz:
https://doaj.org/article/2180e40458624feab5dd8729c5eae078
Autor:
Dandan Zhu, Haihong Wang, Wei Wu, Shuaipeng Geng, Guolin Zhong, Yunfei Li, Han Guo, Guanghui Long, Qingqi Ren, Yi Luan, Chaohui Duan, Bing Wei, Jie Ma, Shiyong Li, Jun Zhou, Mao Mao
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background Circulating cell-free DNA (cfDNA) is a pool of short DNA fragments mainly released from apoptotic hematopoietic cells. Nevertheless, the precise physiological process governing the DNA fragmentation and molecular profile of cfDNA
Externí odkaz:
https://doaj.org/article/0f54e3c329094239927b0161d64dbaa0