Zobrazeno 1 - 10
of 1 798
pro vyhledávání: '"chronic unpredictable mild stress"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-36 (2024)
Abstract There is a lack of in-depth research on the impacts and changes in chronic psychological stress (CPS) on the cardiovascular system after acute myocardial infarction (AMI). This study aims to explore the comorbid mechanism and dynamic evoluti
Externí odkaz:
https://doaj.org/article/ef4cdaaa159b4d8db88eaceff5b7915d
Autor:
Li Wang, Fengying Yuan, Qiaoli Yuan, Guidong Dai, Xiaofei Lu, Li Zhou, Yurong Zheng, Yunzhu Wu, Maohua Wang, Guangxiang Chen
Publikováno v:
Heliyon, Vol 10, Iss 23, Pp e40428- (2024)
Background: Several clinical neuroimaging studies have reported structural and functional brain abnormalities associated with peripheral inflammatory cytokines or kynurenine pathway metabolites in patients with depression. However, it is not clear wh
Externí odkaz:
https://doaj.org/article/485a8d1149014759b6e06e47eb29e179
Autor:
Fangyuan Liang, Suzhen Liu, Heng Zhang, Ronglan Xiang, Mengting Xie, Xiaoru He, Sunyi Wang, Song Wu, Jia Li
Publikováno v:
Stress, Vol 27, Iss 1 (2024)
Stress has been linked to the development of irritable bowel syndrome (IBS), and various methods have been explored to model IBS in combination with other stimuli. However, it remains unclear whether stress alone can induce IBS in animals. This study
Externí odkaz:
https://doaj.org/article/3957bf7a314945518e329818a78349a0
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 41, Iss , Pp 100856- (2024)
Depression is a psychological disorder associated with prolonged stress, which involves abnormal activation of the hypothalamic-pituitary-adrenal (HPA) axis, leading to elevated levels of glucocorticoids (GC). Excessive GC can cause damage to the str
Externí odkaz:
https://doaj.org/article/235fab6e78074a87bc626ec244c13d24
Autor:
Qingyi Ren, Chenxi He, Yuhong Sun, Xiaowei Gao, Yan Zhou, Tao Qin, Zhuo Zhang, Xiaodong Wang, Jun Wang, Siping Wei, Fang Wang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundAsiaticoside, the main active ingredient of Centella asiatica, is a pentacyclic triterpenoid compound. Previous studies have suggested that asiaticoside possesses neuroprotective and anti-depressive properties, however, the mechanism of its
Externí odkaz:
https://doaj.org/article/6ac7f3082b124dcd9f470e4a0dfa4371
Autor:
Masayoshi Okada, Thi Thu Thuy Tran
Publikováno v:
IBRO Neuroscience Reports, Vol 16, Iss , Pp 622-628 (2024)
We have previously shown that a single dose of a TREK-1 channel activator, ostruthin, exhibited antidepressant and anxiolytic effects in acute behavioral test models in mice. To assess the potential clinical application, it is essential to evaluate t
Externí odkaz:
https://doaj.org/article/19df78b0fba044d7b83edab7de01b758
Autor:
Chen Li, Hailong Ge, Junjie Huang, Lujia Si, Limin Sun, Lan Wu, Ling Xiao, Yinping Xie, Gaohua Wang
Publikováno v:
Brain Research Bulletin, Vol 220, Iss , Pp 111136- (2025)
Major depressive disorder (MDD) is common, and successful treatment remains challenging. Resveratrol, a naturally occurring polyphenol, has been shown to alleviate depression-like behaviors, but the underlying mechanisms remain unclear. We previously
Externí odkaz:
https://doaj.org/article/64944aca373c4c18a17cdef9e7167d21
Autor:
Jingqi Zhao, Jiahu Yuan, Yihua Zhang, Langni Deng, Yajing Pan, Xiaojia Bai, Longgang Jia, Yanping Wang, Weitao Geng
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
IntroductionSeveral studies indicated that depression is associated with liver injury. The role of probiotics in alleviating depression is focused on improving the abnormalities of the central nervous system through the gut-brain axis, while the effe
Externí odkaz:
https://doaj.org/article/434769ab38604bf08d239d373ce2a98c
Autor:
Ruolan Huang, Shenglan Gong, Bocheng Xiong, Xifei Yang, Chongyang Chen, Wei Song, Ruodai Wu, Li Yang, Jia Yin, Mingtai Chen
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34596- (2024)
Background: Xiaoyaosan (XYS), a renowned classical traditional Chinese medicinal formula utilized in addressing major depressive disorder (MDD), has garnered significant acclaim for its remarkable efficacy in clinical application. The onset of major
Externí odkaz:
https://doaj.org/article/5f342ee9db2c416a928bebe56b57a427
Autor:
Jingyi Xu, Lei Zhou, Zhaowei Chen, Yuezhu Wang, Fang Xu, Qun Kuang, Yixuan Zhang, Huajun Zheng
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: The prevalence of major depressive disorder (MDD) has gradually increased and has attracted widespread attention. The aim of this study was to investigate the effect of a probiotic compound consisting of Bacillus coagulans and Clostridi
Externí odkaz:
https://doaj.org/article/f488c10d0b7a410abb383e188b07c44a