Zobrazeno 1 - 10
of 1 095
pro vyhledávání: '"chronic lung allograft dysfunction"'
Autor:
Christian Martin, Kathleen S. Mahan, Talia D. Wiggen, Adam J. Gilbertsen, Marshall I. Hertz, Ryan C. Hunter, Robert A. Quinn
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-12 (2024)
Abstract Background Progression of chronic lung disease may lead to the requirement for lung transplant (LTx). Despite improvements in short-term survival after LTx, chronic lung allograft dysfunction (CLAD) remains a critical challenge for long-term
Externí odkaz:
https://doaj.org/article/f2779c4e36f2402580fa37a1dee2c5bf
Autor:
Kyoto Matsudo, Shinkichi Takamori, Tomoyoshi Takenaka, Mototsugu Shimokawa, Asato Hashinokuchi, Taichi Nagano, Fumihiko Kinoshita, Takaki Akamine, Mikihiro Kohno, Gouji Toyokawa, Tomoharu Yoshizumi
Publikováno v:
Transplant International, Vol 37 (2024)
Bronchiolitis obliterans syndrome (BOS) is a chronic complication following lung transplantation that limits the long-term survival. Although the enhancer of zeste homolog 2 (EZH2) is involved in post-transplantation rejection, its involvement in BOS
Externí odkaz:
https://doaj.org/article/dce38c74c0ee4660b3f58facc7fa95e4
Autor:
Mary A. Neal, PhD, Saskia Bos, MD, PhD, Charlotte W. Holland, MRCP, Kieren G. Hollingsworth, Gerard Meachery, FRCP, Arun Nair, MD, FRCP, James L. Lordan, FRCP, Andrew J. Fisher, FRCP, PhD, Peter E. Thelwall, PhD
Publikováno v:
JHLT Open, Vol 7, Iss , Pp 100167- (2025)
Background: By the time chronic lung allograft dysfunction (CLAD), with its main phenotypes bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS), is diagnosed by pulmonary function testing, irreversible damage to the lung
Externí odkaz:
https://doaj.org/article/b3d1eca48bfe4574a1daa60f1cc0877f
Autor:
David Bennett, Matteo Fanetti, Maddalena Messina, Barbara Toniella Corradini, Asma Bendjeddou, Samuele Ferrari, Felice Perillo, Luca Luzzi, Piero Paladini, Elena Marchini, Elena Bargagli, Antonella Fossi
Publikováno v:
JHLT Open, Vol 5, Iss , Pp 100106- (2024)
Background: Extracorporeal photopheresis (ECP) is considered an emerging rescue therapy for patients with chronic lung allograft dysfunction (CLAD). The aim of the study was to set up a web-based data collection tool for lung transplant patients with
Externí odkaz:
https://doaj.org/article/ef6a2a8d53bf46e5899ad356ecc0228f
Safety and efficacy of delaying lung transplant surgery to a morning startCentral MessagePerspective
Autor:
Samuel T. Kim, BA, Yu Xia, MD, MS, Peter D. Cho, BS, Jonathan K. Ho, MD, Swati Patel, MD, Christine Lee, RN, Abbas Ardehali, MD
Publikováno v:
JTCVS Open, Vol 16, Iss , Pp 1008-1017 (2023)
Objective: We aimed to evaluate the safety and efficacy of delaying lung transplantation until morning for donors with cross-clamp times occurring after 1:30 am. Methods: All consented adult lung transplant recipients between March 2018 and May 2022
Externí odkaz:
https://doaj.org/article/e3ca1281104f440cbce99205cd855f75
Publikováno v:
Viruses, Vol 16, Iss 10, p 1574 (2024)
Chronic lung allograft dysfunction (CLAD) is the most common cause of long-term lung allograft failure. Several factors, including respiratory virus infection (RVI), have been associated with CLAD development, but the underlying mechanisms of these a
Externí odkaz:
https://doaj.org/article/3fc182f5565f459fbd32da1f30d56f90
Autor:
Auyon J. Ghosh, MD, MPH, Matthew Moll, MD, MPH, Shikshya Shrestha, PhD, Sergio Poli, MD, Stephen J. Glatt, PhD, Hilary J. Goldberg, MD, Andrew M. Courtwright, MD, Souheil Y. El-Chemaly, MD
Publikováno v:
JHLT Open, Vol 4, Iss , Pp 100081- (2024)
Acute cellular rejection (ACR) is one of the main risk factors for chronic allograft dysfunction, the primary contributor to poor long-term survival in lung transplant recipients. We sought to develop a blood-based transcriptomic risk score (TRS) to
Externí odkaz:
https://doaj.org/article/bb29725f0f1b4a8fae559b9f86c175c5
Autor:
Pieterjan Kerckhof, Gene P.L. Ambrocio, Hanne Beeckmans, Janne Kaes, Vincent Geudens, Saskia Bos, Lynn Willems, Astrid Vermaut, Marie Vermant, Tinne Goos, Charlotte De Fays, Lucia Aversa, Yousry Mohamady, Arno Vanstapel, Michaela Orlitová, Jan Van Slambrouck, Xin Jin, Vimi Varghese, Iván Josipovic, Matthieu N. Boone, Lieven J. Dupont, Birgit Weynand, Adriana Dubbeldam, Dirk E. Van Raemdonck, Laurens J. Ceulemans, Ghislaine Gayan-Ramirez, Laurens J. De Sadeleer, John E. McDonough, Bart M. Vanaudenaerde, Robin Vos
Publikováno v:
EBioMedicine, Vol 101, Iss , Pp 105030- (2024)
Summary: Background: Chronic lung allograft dysfunction (CLAD) encompasses three main phenotypes: bronchiolitis obliterans syndrome (BOS), restrictive allograft syndrome (RAS) and a Mixed phenotype combining both pathologies. How the airway structure
Externí odkaz:
https://doaj.org/article/74c39f4f6a8f4b25a9a6b0237861612e
Publikováno v:
Advances in Respiratory Medicine, Vol 91, Iss 5, Pp 432-444 (2023)
Background: Chronic lung allograft dysfunction (CLAD) is the leading cause of death after the first postoperative years of lung transplantation (LTx). Objective: To assess the number of disability-adjusted life years (DALYs) per patient with severe C
Externí odkaz:
https://doaj.org/article/b875fcdb3cde449587ba5e3a77d0ab65
Autor:
Dong Tian, Xiangyun Zheng, Hongtao Tang, Heng Huang, Junjie Wang, Lin Xu, Caihan Li, Haoji Yan, Ruixuan Yu, Jinzhu Nan, Menggen Liu, Xiaoguang Guo, Shunhai Jian, Tao Wang, Senyi Deng, Qiang Pu, Lunxu Liu
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background Chronic lung allograft dysfunction (CLAD) directly causes an abysmal long-term prognosis after lung transplantation (LTx), but effective and safe drugs are not available. Metformin exhibits high therapeutic potential due to its an
Externí odkaz:
https://doaj.org/article/21e48ea4af9b40529053381f7079511c