Zobrazeno 1 - 10
of 548
pro vyhledávání: '"chronic itch"'
Autor:
Anusha Kambala, BS, Alexander L. Kollhoff, MD, Elena Wei, BS, Kevin K. Lee, BA, Hannah Cornman, BS, Emily Z. Ma, BA, Jaya Manjunath, BS, Brenda Umenita Imo, MS, Sriya V. Reddy, BS, Shawn G. Kwatra, MD
Publikováno v:
JAAD Case Reports, Vol 44, Iss , Pp 77-81 (2024)
Externí odkaz:
https://doaj.org/article/2faa9e70b3b145f29db86d8df4afd22c
Autor:
Sarah G. Brooks, Gil Yosipovitch
Publikováno v:
Journal of Dermatological Treatment, Vol 35, Iss 1 (2024)
Purpose Pruritus is an unpleasant sensation that creates the urge to scratch. In many chronic conditions, relentless pruritus and scratching perpetuates a vicious itch-scratch cycle. Uncontrolled itch can detrimentally affect quality of life and may
Externí odkaz:
https://doaj.org/article/8e005beff78a482f91e1446f9434e6f9
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Atopic dermatitis (AD) is one of the most prevalent intractable chronic itch diseases worldwide. In recent years, new molecular-targeted drugs have emerged, but side effects and economic challenges remain. Therefore, since it is importa
Externí odkaz:
https://doaj.org/article/824c3499d06c46ecbf4938ab3dff76f7
Publikováno v:
Clinical Dermatology Review, Vol 8, Iss 2, Pp 87-94 (2024)
Small-fiber neuropathy (SFN) develops due to the impairment of fibers responsible for mediating temperature, pain, and autonomic functions. SFN complicates a number of common diseases such as diabetes mellitus, human immunodeficiency virus, and COVID
Externí odkaz:
https://doaj.org/article/15d7d093df09474baa47357c70b6d098
Autor:
Sonja Ständer, Thomas Luger, Brian Kim, Ethan Lerner, Martin Metz, Roni Adiri, Juliana M. Canosa, Amy Cha, Gil Yosipovitch
Publikováno v:
Dermatology and Therapy, Vol 14, Iss 1, Pp 45-57 (2024)
Abstract Atopic dermatitis (AD) is a chronic, relapsing immunoinflammatory skin condition characterized by sensations such as pruritis, pain, and neuronal hypersensitivity. The mechanisms underlying these sensations are multifactorial and involve com
Externí odkaz:
https://doaj.org/article/7b175ccefefa490a830ec1ae1f30a7f0
Autor:
Rui Chen, Xiang Xu, Xin-Yue Wang, Wen-Bin Jia, De-Shan Zhao, Na Liu, Zhen Pang, Xiao-Qing Liu, Yan Zhang
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-13 (2023)
Abstract Itch is a complex aversive sensory and emotional experience. As a most upsetting symptom in many dermatological and systemic diseases, it lacks efficient treatments. The lateral habenula nucleus (LHb) encodes negative emotions in the epithal
Externí odkaz:
https://doaj.org/article/0b099c8fca2249539f15ef411215c74e
Autor:
Nan Li, Chunyan Wang, Yuying Zhao, Yigang Wang, Tianyu Gao, Yonghao Yu, Guolin Wang, Linlin Zhang
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-21 (2023)
Abstract Background Patients receiving epidural or intrathecal opioids administration for neuraxial analgesia frequently suffer from an irritating itch. STING (stimulator of interferon genes), an innate immune modulator, is strongly implicated in pai
Externí odkaz:
https://doaj.org/article/0fa827d0d9614958ba990bee7d625212
Autor:
Tang Li, Lingyue Hu, Chao Qin, Yuanjie Li, Zhenhua Song, Yang Jiao, Chunyan Wang, Wei Cui, Linlin Zhang
Publikováno v:
Brain Sciences, Vol 14, Iss 5, p 440 (2024)
The unclear pathogenesis of chronic itch originating from several systemic disorders poses challenges to clinical intervention. Recent studies recapitulate the spinal neurocircuits associated with neuroinflammation and synaptic plasticity responsible
Externí odkaz:
https://doaj.org/article/877799a207d442be8685b6389eacd75d
Autor:
Madison R. Mack, Yannick Miron, Fanny Chen, Paul E. Miller, Annie Zhang, Andrew Korotzer, Daniel Richman, Paul J. Bryce
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
IntroductionChronic itch is a central symptom of atopic dermatitis. Cutaneous afferent neurons express receptors interleukins (IL)-4, IL-13, and IL-33, which are type 2 cytokines that are elevated in atopic dermatitis. These neuronal cytokine recepto
Externí odkaz:
https://doaj.org/article/437ae312b43144a29ba413ca065680ec
Autor:
Parisa Gazerani
Publikováno v:
Neuroglia, Vol 4, Iss 1, Pp 15-27 (2023)
Chronic itch (CI) is an unpleasant skin sensation accompanied by an intense scratching desire that lasts 6 weeks or longer. Despite the high prevalence and negative impact on affected individuals and a huge healthcare burden, CI mechanisms are only p
Externí odkaz:
https://doaj.org/article/cd05e22b8f4948a5888be86823f69a8e