Zobrazeno 1 - 10
of 423
pro vyhledávání: '"chronic allograft dysfunction"'
Publikováno v:
Alexandria Journal of Medicine, Vol 60, Iss 1, Pp 249-258 (2024)
Background Chronic allograft dysfunction (CAD) represents a complex process of inflammatory response, fibrosis, and tissue restoration, mediated by a myriad of proinflammatory cytokines, enzymes, and growth factors. NOD-like receptor protein3 (NLRP3)
Externí odkaz:
https://doaj.org/article/81b297e748a548ce964ff11c33624852
Autor:
Jianjian Zhang, Weibin Xie, Bin Ni, Zhuohang Li, Dengyuan Feng, Yao Zhang, Qianguang Han, Hai Zhou, Min Gu, Ruoyun Tan
Publikováno v:
Pharmacological Research, Vol 200, Iss , Pp 107051- (2024)
Renal interstitial fibrosis/tubular atrophy (IF/TA) is a prominent pathological feature of chronic allograft dysfunction (CAD). Our previous study has demonstrated that epithelial-mesenchymal transition (EMT) plays a significant role in shaping the d
Externí odkaz:
https://doaj.org/article/35c74adc66974e878e55487e236914de
Autor:
Rim, Jeeyon G. a, Hellkamp, Anne S. b, Neely, Megan L. b, c, Reynolds, John M. a, Belperio, John A. d, Budev, Marie e, Eason, Lerin a, Frankel, Courtney W. a, Keshavjee, Shaf f, Kirchner, Jerry b, Singer, Lianne G. g, Shah, Pali D. f, Snyder, Laurie D. a, b, Samuel Weigt, S. d, Palmer, Scott M. a, b, Todd, Jamie L. a, b, ⁎
Publikováno v:
In Journal of Heart and Lung Transplantation
Publikováno v:
Renal Failure, Vol 45, Iss 1 (2023)
AbstractOur research explores the role of M1 macrophage polarization in endothelium-to-myofibroblast transition (EndMT) and chronic allograft dysfunction (CAD). GSE21374 transcriptome sequencing data were obtained. Transplanted nephrectomy specimens
Externí odkaz:
https://doaj.org/article/e3c647afcff54270bc8dd4a7f54779f4
Publikováno v:
Renal Failure, Vol 44, Iss 1, Pp 1585-1594 (2022)
Objective Our study was designed to explore the role of Cyclophilin A (CyPA)/CD147 signaling in renal allograft fibrosis and chronic allograft dysfunction (CAD).Materials and methods A rat renal transplant model with significant CAD was successfully
Externí odkaz:
https://doaj.org/article/af13c81d074a4eab8e6414a258382979
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundChronic allograft dysfunction(CAD) is the leading cause of graft loss in kidney transplant recipients (KTRs). Inflammatory process is believed to be one of the major contributors to CAD. The aim of this study is to explore the anti-inflamma
Externí odkaz:
https://doaj.org/article/ca700aa702304db4a8b834d70f1fec69
Autor:
Madhusudhanan Narasimhan, Alagarraju Muthukumar, Kavithalakshmi Sataranatarajan, Lenin Mahimainathan, Luke Mahan, Irina Timofte, Srinivas Bollineni, John Joerns, Song Zhang, April Gorman, Amit Banga, Manish Mohanka, Fernando Torres, Adrian Lawrence, Mohanakumar Thalachallour, Vaidehi Kaza
Publikováno v:
Viruses, Vol 15, Iss 10, p 2045 (2023)
The presence of a certain group of auto-antibodies (AAbs) is known to correlate with the severity of COVID-19. It is, however, unknown if such AAbs are prevalent and impact COVID-19-related outcomes in lung transplant recipients (LTRs) who are immuno
Externí odkaz:
https://doaj.org/article/dd17f06550e441f5a1188343701ffae4
Autor:
Rasha Ibrahim Abdel Razek Gawish, Hayam Abdel Meguid El Aggan, Sabah Abdel Hady Mahmoud, Sara Ahmed Mohamed Mortada
Publikováno v:
The Egyptian Journal of Internal Medicine, Vol 32, Iss 1, Pp 1-11 (2020)
Abstract Background Chronic allograft dysfunction (CAD) is considered the leading cause of late allograft loss. The cluster of differentiation 47 (CD47) and calreticulin (CRT) are involved in many and diverse cellular processes. The present study was
Externí odkaz:
https://doaj.org/article/48ae477aa848455eb20332c4cf0907a7
Akademický článek
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Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Fibrosis contributes to graft loss in chronic renal allograft injury. Endothelial‐to‐mesenchymal transition (EndMT) plays an important role in the development of fibrosis following kidney transplantation. Autophagy plays an important role in the
Externí odkaz:
https://doaj.org/article/6b6aad5e4a9245dd9da2937368caa98a