Circular intermediate-mediated horizontal transfer of the chromosome-encoded cfr(C) gene in multi-drug resistant Campylobacter coli from swine sources

Autor: Jae-Uk An, Soomin Lee, Jae-Ho Guk, Jungha Woo, Hyokeun Song, Seongbeom Cho

Publikováno v: Frontiers in Microbiology, Vol 14 (2023)

Campylobacter is a major zoonotic pathogen that causes gastrointestinal and, rarely, immune diseases in humans. The antimicrobial-resistance gene cfr(C) carried by Campylobacter and is a cfr-like gene that targets bacterial 23S rRNA through A2503 met

Externí odkaz: https://doaj.org/article/91014ef974864a8fb3ee0aea97b3ba3f

Disruption of FOXP3–EZH2 Interaction Represents a Pathobiological Mechanism in Intestinal InflammationSummary

Autor: Gwen Lomberk, Adebowale O. Bamidele, Mary R. Sagstetter, Manuel Bonfim Braga Neto, Olga F. Sarmento, Subra Kugathasan, Raul Urrutia, Michelle Gonzalez, William A. Faubion, Phyllis A. Svingen

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 55-71 (2019)
Cellular and Molecular Gastroenterology and Hepatology

Background & Aims: Forkhead box protein 3 (FOXP3)+ regulatory T cell (Treg) dysfunction is associated with autoimmune diseases; however, the mechanisms responsible for inflammatory bowel disease pathophysiology are poorly understood. Here, we tested

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f12e433b1850cff302bda788632ed012
http://www.sciencedirect.com/science/article/pii/S2352345X18301267

The transcriptional activity profile of inhibitor apoptosis protein encoding genes in colon cancer patients

Autor: Magda Bichalska-Lach, Zbigniew Lorenc, Dariusz Waniczek, Marcin Nowak, Justyna Lorenc-Góra, Małgorzata Muc-Wierzgoń, Urszula Mazurek

Publikováno v: Medicine

The inhibitor of apoptosis family proteins (IAPs) plays a crucial role in the process of carcinogenesis by regulating apoptosis and maintaining the tissue balance. In this study, a transcriptomic analysis of IAP-encoding genes in colon cancer was per

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9fede12ffa606e6d39bee22f8bddfa7
https://doi.org/10.1097/md.0000000000027882

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Disruption of FOXP3-EZH2 Interaction Represents a Pathobiological Mechanism in Intestinal Inflammation.

Autor: Bamidele AO; Epigenetics and Chromatin Dynamics Laboratory, Division of Gastroenterology and Hepatology and Translational Epigenomic Program, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota., Svingen PA; Epigenetics and Chromatin Dynamics Laboratory, Division of Gastroenterology and Hepatology and Translational Epigenomic Program, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota., Sagstetter MR; Epigenetics and Chromatin Dynamics Laboratory, Division of Gastroenterology and Hepatology and Translational Epigenomic Program, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota., Sarmento OF; Epigenetics and Chromatin Dynamics Laboratory, Division of Gastroenterology and Hepatology and Translational Epigenomic Program, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota., Gonzalez M; Epigenetics and Chromatin Dynamics Laboratory, Division of Gastroenterology and Hepatology and Translational Epigenomic Program, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota., Braga Neto MB; Epigenetics and Chromatin Dynamics Laboratory, Division of Gastroenterology and Hepatology and Translational Epigenomic Program, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota., Kugathasan S; Department of Pediatrics, Emory University, School of Medicine, Atlanta, Georgia., Lomberk G; Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin., Urrutia RA; Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin., Faubion WA Jr; Epigenetics and Chromatin Dynamics Laboratory, Division of Gastroenterology and Hepatology and Translational Epigenomic Program, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota. Electronic address: Faubion.William@mayo.edu.

Publikováno v: Cellular and molecular gastroenterology and hepatology [Cell Mol Gastroenterol Hepatol] 2018 Sep 14; Vol. 7 (1), pp. 55-71. Date of Electronic Publication: 2018 Sep 14 (Print Publication: 2019).